Catalog No.
RHC95208
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
CD324, Uvomorulin, Epithelial cadherin, E-cadherin, CDHE, CAM 120/80, UVO, CDH1, Cadherin-1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P12830
Applications
ELISA, FCM, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3C98
Aberrant E-cadherin Expression in Lobular Carcinoma In Situ: A Comprehensive Immunohistochemical Evaluation of N-terminal, Extracellular, and C-terminal E-cadherin Domains., PMID:39807823
IL-8 promotes lens capsular residual cells migration by down-regulates expression of E-cadherin and ZO-1 via the CXCR1/2-NF-κB-RhoA signal pathway., PMID:39244903
Advantages of automated immunostain analyses for complex membranous immunostains: An exemplar investigating loss of E-cadherin expression in colorectal cancer., PMID:39032383
E-Cadherin Mutational Landscape and Outcomes in Breast Invasive Lobular Carcinoma., PMID:39025406
E-Cadherin Induces Serine Synthesis to Support Progression and Metastasis of Breast Cancer., PMID:38959339
Molecular Landscape and Clinical Implication of CCNE1-amplified Esophagogastric Cancer., PMID:38717153
Targeting tumorous Circ-E-Cadherinencoded C-E-Cad inhibits the recruitment and function of breast cancer-associated myeloid-derived suppressor cells., PMID:38704109
Integration of Pathological Criteria and Immunohistochemical Evaluation for Invasive Lobular Carcinoma Diagnosis: Recommendations From the European Lobular Breast Cancer Consortium., PMID:38641322
Stabilization of E-cadherin adhesions by COX-2/GSK3β signaling is a targetable pathway in metastatic breast cancer., PMID:36757813
Immunohistochemical expression of E-cadherin, N-cadherin and Snail/slug in ameloblastoma., PMID:35659530
Comparison of Fixation Methods for the Detection of Claudin 1 and E-Cadherin in Breast Cancer Cell Lines by Immunofluorescence., PMID:34715746
Expression of N-Terminal-Deficient E-Cadherin Protein in Invasive Lobular Carcinoma of the Breast., PMID:34653059
Multiplexed DNA-Directed Patterning of Antibodies for Applications in Cell Subpopulation Analysis., PMID:34546726
Dynamic Imaging of IEL-IEC Co-Cultures Allows for Quantification of CD103-Dependent T Cell Migration., PMID:34067987
Rare germline variants in the E-cadherin gene CDH1 are associated with the risk of brain tumors of neuroepithelial and epithelial origin., PMID:33929593
"Switch of E-Cadherin to N-Cadherin expression in different molecular subtypes of breast invasive duct carcinomas and its correlation with clinicopathological features"., PMID:33433407
Effect of DNMT3A polymorphisms on CpG island hypermethylation in gastric mucosa., PMID:33066747
A novel immunohistochemical scoring system reveals associations of C-terminal MET, ectodomain shedding, and loss of E-cadherin with poor prognosis in oral squamous cell carcinoma., PMID:32702402
Three-dimensional analysis of extrahepatic cholangiocarcinoma and tumor budding., PMID:32476131
Enhancement of aberrantly modified integrin‑mediated cell motility in multicellular tumor spheroids., PMID:32236635
BACH1 Promotes Pancreatic Cancer Metastasis by Repressing Epithelial Genes and Enhancing Epithelial-Mesenchymal Transition., PMID:31919242
Three-dimensional visualization of cleared human pancreas cancer reveals that sustained epithelial-to-mesenchymal transition is not required for venous invasion., PMID:31700162
Photocleavable Cadherin Inhibits Cell-to-Cell Mechanotransduction by Light., PMID:31503442
E-cadherin is required for metastasis in multiple models of breast cancer., PMID:31485072
Stromal fibroblasts induce metastatic tumor cell clusters via epithelial-mesenchymal plasticity., PMID:31331982
RNF43 ubiquitinates and degrades phosphorylated E-cadherin by c-Src to facilitate epithelial-mesenchymal transition in lung adenocarcinoma., PMID:31286874
E-cadherin clone 36 nuclear staining dictates adverse disease outcome in lobular breast cancer patients., PMID:31231125
E-Cadherin Is Important for Meibomian Gland Function as Revealed by a New Human ex Vivo Slice Culture Model., PMID:31121132
CCL2 promotes cell migration by inducing epithelial-mesenchymal transition in oral squamous cell carcinoma., PMID:31077446
Glutamate Ionotropic Receptor Kainate Type Subunit 3 (GRIK3) promotes epithelial-mesenchymal transition in breast cancer cells by regulating SPDEF/CDH1 signaling., PMID:30977227
Flavokawain B targets protein neddylation for enhancing the anti-prostate cancer effect of Bortezomib via Skp2 degradation., PMID:30885218
Varicella Zoster Virus Alters Expression of Cell Adhesion Proteins in Human Perineurial Cells via Interleukin 6., PMID:30835269
Cellular proliferation in mouse and human pancreatic islets is regulated by serpin B13 inhibition and downstream targeting of E-cadherin by cathepsin L., PMID:30824970
Voltammetric immunosensor for E-cadherin promoter DNA methylation using a Fe3O4-citric acid nanocomposite and a screen-printed carbon electrode modified with poly(vinyl alcohol) and reduced graphene oxide., PMID:30741341
M1-Polarized Macrophages Promote Self-Renewing Phenotype of Hepatic Progenitor Cells with Jagged1-Notch Signalling Involved: Relevance in Primary Sclerosing Cholangitis., PMID:30671485
CD103 (αE Integrin) Undergoes Endosomal Trafficking in Human Dendritic Cells, but Does Not Mediate Epithelial Adhesion., PMID:30622531
Prognostic significance of E-cadherin expression in hepatocellular carcinoma: correlations with clinical features., PMID:32239101
Prognostic significance of cell-adhesion molecules in histological variants of papillary thyroid carcinoma., PMID:30534810
[LIMR is involved in the inhibitory effect of antiflammin-1 on epithelial-mesenchymal transition in A549 cells]., PMID:30377686
Phenotypic and molecular dissection of metaplastic breast cancer and the prognostic implications., PMID:30350370
Phosphorylation of MCPH1 isoforms during mitosis followed by isoform-specific degradation by APC/C-CDH1., PMID:30303738
Chemoresistance of cancer floating cells is independent of their ability to form 3D structures: Implications for anticancer drug screening., PMID:30191978
An extracellular Leptospira interrogans leucine-rich repeat protein binds human E- and VE-cadherins., PMID:30171791
HER2 Activation Factors in Arsenite-Exposed Bladder Epithelial Cells., PMID:30137596
Decreased E-Cadherin in MCF7 Human Breast Cancer Cells Forming Multicellular Spheroids Exposed to Simulated Microgravity., PMID:29785723
The HER4-YAP1 axis promotes trastuzumab resistance in HER2-positive gastric cancer by inducing epithelial and mesenchymal transition., PMID:29535422
Lightsheet fluorescence microscopy of branching human fetal kidney., PMID:29389399
Integration of pan-cancer transcriptomics with RPPA proteomics reveals mechanisms of epithelial-mesenchymal transition., PMID:29293502
A new mutation of the CDH1 gene in a patient with an aggressive signet-ring cell carcinoma of the stomach., PMID:29131691
MDM2 promotes epithelial-mesenchymal transition and metastasis of ovarian cancer SKOV3 cells., PMID:28817834
For research use only. Not for human or drug use.
