Catalog No.
RHC82603
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:25-1:200
Target
cAMP-dependent protein kinase type I-alpha regulatory subunit, TSE1, PRKAR1A, Tissue-specific extinguisher 1, PKR1, PRKAR1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P10644
Applications
IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3C18
From cortisol-producing adrenal adenoma to atrial myxoma, through nivolumab-induced hypophysitis: a complicated case report of Carney Complex., PMID:39217593
Lipodystrophy in methylmalonic acidemia associated with elevated FGF21 and abnormal methylmalonylation., PMID:38271099
Identification of antigenic epitopes recognized by tumor infiltrating lymphocytes in high grade serous ovarian cancer by multi-omics profiling of the auto-antigen repertoire., PMID:36943460
Sporadic superficial angiomyxomas demonstrate loss of PRKAR1A expression., PMID:34532875
Checkpoint inhibitors and radiotherapy in refractory malignant melanocytic schwannoma with Carney complex: first evidence of efficacy., PMID:34049890
Mitochondrial E3 ligase March5 maintains stemness of mouse ES cells via suppression of ERK signalling., PMID:26033541
Primary pigmented nodular adrenocortical disease: the original 4 cases revisited after 30 years for follow-up, new investigations, and molecular genetic findings., PMID:24805858
Malignant melanotic schwannian tumor: a clinicopathologic, immunohistochemical, and gene expression profiling study of 40 cases, with a proposal for the reclassification of "melanotic schwannoma"., PMID:24145644
PRKAR1A overexpression is associated with increased ECPKA autoantibody in liver fluke-associated cholangiocarcinoma: application for assessment of the risk group., PMID:22922884
PRKAR1A mutation affecting cAMP-mediated G protein-coupled receptor signaling in a patient with acrodysostosis and hormone resistance., PMID:22723333
Tissue-specific ablation of Prkar1a causes schwannomas by suppressing neurofibromatosis protein production., PMID:18953430
Detection of somatic beta-catenin mutations in primary pigmented nodular adrenocortical disease (PPNAD)., PMID:18419788
Loss of expression of protein kinase a regulatory subunit 1alpha in pigmented epithelioid melanocytoma but not in melanoma or other melanocytic lesions., PMID:18059235
Mutation of Prkar1a causes osteoblast neoplasia driven by dysregulation of protein kinase A., PMID:17932105
Primary pigmented nodular adrenocortical disease reveals insulin-like growth factor binding protein-2 regulation by protein kinase A., PMID:17280861
An active protein kinase A (PKA) is involved in meiotic arrest of rat growing oocytes., PMID:16816331
Identification and characterization of novel PKA holoenzymes in human T lymphocytes., PMID:15794744
Localization of Triton-insoluble cAMP-dependent kinase type RIbeta in rat and mouse brain., PMID:12373096
Aggregates of cAMP-dependent kinase RIalpha characterize a type of cholinergic neurons in the rat brain., PMID:11038256
Localization of cAMP-dependent signal transducers in early rat liver carcinogenesis., PMID:9541468
Cyclic AMP-dependent protein kinase (cAK) in human B cells: co-localization of type I cAK (RI alpha 2 C2) with the antigen receptor during anti-immunoglobulin-induced B cell activation., PMID:8647207
The differential response of protein kinase A to cyclic AMP in discrete brain areas correlates with the abundance of regulatory subunit II., PMID:8627334
Characterization of in-vitro-translated human regulatory and catalytic subunits of cAMP-dependent protein kinases., PMID:8119290
Cellular location and age-dependent changes of the regulatory subunits of cAMP-dependent protein kinase in rat testis., PMID:8107013
Novel isozymes of cAMP-dependent protein kinase exist in human cells due to formation of RI alpha-RI beta heterodimeric complexes., PMID:8407966
Dibutyryl cAMP treatment of neuroblastoma-glioma hybrid cells results in selective increase in cAMP-receptor protein (R-I) as measured by monospecific antibodies., PMID:11894919
For research use only. Not for human or drug use.
