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Anti-Gal1/LGALS1 Antibody (R3B59)

Catalog #:   RHC40105 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM, IHC
Accession: P09382
Overview

Catalog No.

RHC40105

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000

Target

HLBP14, Lactose-binding lectin 1, LGALS1, HBL, HPL, Beta-galactoside-binding lectin L-14-I, Gal-1, Lectin galactoside-binding soluble 1, Putative MAPK-activating protein PM12, S-Lac lectin 1, Galaptin, Galectin-1, 14 kDa laminin-binding protein, 14 kDa lectin

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P09382

Applications

ELISA, FCM, IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3B59

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Hela cells using LGALS1 mouse mAb (green) and negative control (red).
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human lung cancer tissues using LGALS1 mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissues using LGALS1 mouse mAb with DAB staining.
References

New insight for ulcerative colitis diagnosis via serum netrin-1 and galectin-1 biomarkers., PMID:40518925

The Immunomodulatory Role of Galectin-1 in the Tumour Microenvironment and Strategies for Therapeutic Applications., PMID:40507367

Glycosylation-driven programs coordinate immunoregulatory and pro-angiogenic functions of myeloid-derived suppressor cells., PMID:40381622

Nuclear Galectin-1 promotes KRAS-dependent activation of pancreatic cancer stellate cells., PMID:40172967

Galectin-1-Induced Tumor Associated Macrophages Repress Antitumor Immunity in Hepatocellular Carcinoma Through Recruitment of Tregs., PMID:39853961

Impact of galectin-1's redox state on its lectin activity and monomer-dimer equilibrium. Focusing on oxidized Gal-1., PMID:39755294

Ganoderic acid T, a Ganoderma triterpenoid, modulates the tumor microenvironment and enhances the chemotherapy and immunotherapy efficacy through downregulating galectin-1 levels., PMID:39142358

Pre-B cell receptor acts as a selectivity switch for galectin-1 at the pre-B cell surface., PMID:39058594

Circulating immune-related proteins associated with immune checkpoint inhibitor efficacy in patients with pancreatic ductal adenocarcinoma., PMID:38838501

Noninvasively Deciphering the Immunosuppressive Tumor Microenvironment Using Galectin-1 PET to Inform Immunotherapy Responses., PMID:38514084

Mesenchymal stromal cells plus basiliximab improve the response of steroid-refractory acute graft-versus-host disease as a second-line therapy: a multicentre, randomized, controlled trial., PMID:38413930

Enzymatically-derived oligo-carrageenans interact with α-Gal antibodies and Galectin-3., PMID:37985065

Generation and characterization of a monoclonal antibody that binds to Galectin-1., PMID:37209931

Targeting galectin-driven regulatory circuits in cancer and fibrosis., PMID:36759557

Circulating galectin-1 delineates response to bevacizumab in melanoma patients and reprograms endothelial cell biology., PMID:36634146

Decoding Strategies to Evade Immunoregulators Galectin-1, -3, and -9 and Their Ligands as Novel Therapeutics in Cancer Immunotherapy., PMID:36555198

Plasma galectins and metabolites in advanced head and neck carcinomas: evidence of distinct immune characteristics linked to hypopharyngeal tumors., PMID:36545254

Prevalence of high affinity naturally occurring IgG2 antibodies against human chorionic gonadotropin and its subunits in patients with ovarian cyst., PMID:36088866

Regulatory T cells, damage-associated molecular patterns, and myeloid-derived suppressor cells in bronchoalveolar lavage fluid interlinked with chronic obstructive pulmonary disease severity: An observational study., PMID:35687771

Soluble CD146 is increased in preeclampsia and interacts with galectin-1 to regulate trophoblast migration through VEGFR2 receptor., PMID:35559998

Role of MDM2, CDK4, BCL2, Parafibromin and Galectin 1 in Differentiating Osteosarcoma from its Benign Fibro-osseous Lesions., PMID:35220546

Vaccination against galectin-1 promotes cytotoxic T-cell infiltration in melanoma and reduces tumor burden., PMID:35018481

Dual electrochemical sensing of spiked virus and SARS-CoV-2 using natural bed-receptor (MV-gal1)., PMID:34836981

Serum galectin-9 could be a potential biomarker in assessing the disease activity of antineutrophil cytoplasmic antibody-associated vasculitis., PMID:34001301

A minigene DNA vaccine encoding peptide epitopes derived from Galectin-1 has protective antitumoral effects in a model of neuroblastoma., PMID:33848518

Characterization of a neutralizing anti-human galectin-1 monoclonal antibody with angioregulatory and immunomodulatory activities., PMID:33006019

Pancreatic Cancer detection via Galectin-1-targeted Thermoacoustic Imaging: validation in an in vivo heterozygosity model., PMID:32802185

Increased serum levels of galectin-9 in patients with chikungunya fever., PMID:32565125

Galectin-1 expression in oral squamous cell carcinoma: An immunohistochemical study., PMID:32508476

Galectin-1 and Galectin-3 Expression in Lesional Skin of Patients With Systemic Sclerosis-Association With Disease Severity., PMID:32501939

Prompting Fab Yeast Surface Display Efficiency by ER Retention and Molecular Chaperon Co-expression., PMID:32039168

No Bull: A Case of Alpha-Gal Syndrome Associated With Buffalo Meat Sensitivity., PMID:31840005

Galectin-1-driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance., PMID:31710313

Anti-inflammatory Property of Galectin-1 in a Murine Model of Allergic Airway Inflammation., PMID:31214624

The opposite roles of PAS-5 and Galectin-1 in immune response during the early infection of Angiostrongylus cantonensis., PMID:29843794

Immunoglobulins from sera of APS patients bind HTR-8/SVneo trophoblast cell line and reduce additional mediators of cell invasion., PMID:29102762

Toward a new and noninvasive diagnostic method of papillary thyroid cancer by using peptide vectorized contrast agents targeted to galectin-1., PMID:28986753

Anti-inflammatory effect of galectin-1 in a murine model of atopic dermatitis., PMID:28664215

Differential protein expression in chicken macrophages and heterophils in vivo following infection with Salmonella Enteritidis., PMID:28623956

Combined Anti-VEGF and Anti-CTLA-4 Therapy Elicits Humoral Immunity to Galectin-1 Which Is Associated with Favorable Clinical Outcomes., PMID:28473314

Galectin-1 expression is associated with tumour immunity and prognosis in gingival squamous cell carcinoma., PMID:28108653

Galectin-1 inhibits oral-intestinal allergy syndrome., PMID:28086216

HyCCAPP as a tool to characterize promoter DNA-protein interactions in Saccharomyces cerevisiae., PMID:27184763

Placental Expression Patterns of Galectin-1, Galectin-2, Galectin-3 and Galectin-13 in Cases of Intrauterine Growth Restriction (IUGR)., PMID:27070577

Galectin-1 is a useful marker for detecting neoplastic squamous cells in oral cytology smears., PMID:26980012

Comparative analyses on expression of galectins1-4, 7-10 and 12 in first trimester placenta, decidua and isolated trophoblast cells in vitro., PMID:26901464

Galectin-1 drives lymphoma CD20 immunotherapy resistance: validation of a preclinical system to identify resistance mechanisms., PMID:26888257

Immunosensor for the ultrasensitive and quantitative detection of bladder cancer in point of care testing., PMID:26777732

Isolation and Flow Cytometric Analysis of Glioma-infiltrating Peripheral Blood Mononuclear Cells., PMID:26650233

Gal-1 silenced trophoblast tumor cells (BeWo) show decreased syncytium formation and different miRNA production compared to non-target silenced BeWo cells., PMID:26418280

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

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For research use only. Not for human or drug use.

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Anti-Gal1/LGALS1 Antibody (R3B59) [RHC40105]
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