Catalog No.
RHC36302
Species reactivity
Human, Mouse
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, WB: 1:500-1:2000
Target
Endonexin II, ENX2, Placental anticoagulant protein 4, PP4, CBP-I, ANXA5, Anchorin CII, PAP-I, Thromboplastin inhibitor, Vascular anticoagulant-alpha, VAC-alpha, Calphobindin I, ANX5, Placental anticoagulant protein I, Annexin V, Annexin-5, Lipocortin V, Annexin A5
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P08758
Applications
ELISA, FCM, IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3B38
S-hydroxychloroquine prevents the antiphospholipid thrombogenic complexes for antiphospholipid syndrome treatment., PMID:40120554
Anti-fibroblast and anti-endothelial cell autoantibodies in pulmonary arterial hypertension (PAH) in patients with connective tissue diseases (CTD)., PMID:39918970
Heterologous expression, purification and generation of specific antibodies for Annexin A8., PMID:39674528
Association of Anti-Annexin A5 Antibody With Pregnancy Outcomes: A Cohort Study: Anti-annexin A5 antibody with pregnancy outcomes., PMID:39381915
Annexin A5 is a novel prognostic biomarker in oral squamous cell carcinoma., PMID:38945807
Coxsackievirus A6 Infection Causes Neurogenic Pathogenesis in a Neonatal Murine Model., PMID:36851724
Long-circulating XTEN864-annexin A5 fusion protein for phosphatidylserine-related therapeutic applications., PMID:34405304
The ABCA1-efferocytosis axis: A new strategy to protect against atherosclerosis., PMID:33741356
Low prevalence of antiannexin A5 antibodies in unprovoked venous thrombosis., PMID:33586909
Overexpression of annexin A5 might guide the gemtuzumab ozogamicin treatment choice in patients with pediatric acute myeloid leukemia., PMID:32636939
Annexin A5 as an immune checkpoint inhibitor and tumor-homing molecule for cancer treatment., PMID:32111835
Corneal Denervation Causes Epithelial Apoptosis Through Inhibiting NAD+ Biosynthesis., PMID:31415077
Induction of DDIT4 Impairs Autophagy Through Oxidative Stress in Dry Eye., PMID:31266058
Absence of Distinct Immunohistochemical Distribution of Annexin A5, C3b, C4d, and C5b-9 in Placentas From Patients With Antiphospholipid Antibodies, Preeclampsia, and Systemic Lupus Erythematosus., PMID:30922166
Antiphospholipid Antibodies in a General Obstetric Population: Clinical Impact on Pregnancy Outcome and Relationship with the M2 Haplotype in the Annexin A5 (ANXA5) Gene., PMID:30304747
Anti-CD73 and anti-OX40 immunotherapy coupled with a novel biocompatible enzyme prodrug system for the treatment of recurrent, metastatic ovarian cancer., PMID:29574275
The effect of hydroxychloroquine on haemostasis, complement, inflammation and angiogenesis in patients with antiphospholipid antibodies., PMID:29045759
Prediction of Antiphospholipid syndrome using Annexin A5 competition assay in patients with SLE., PMID:27704312
Circulating Autoantibodies in Age-Related Macular Degeneration Recognize Human Macular Tissue Antigens Implicated in Autophagy, Immunomodulation, and Protection from Oxidative Stress and Apoptosis., PMID:26717306
Examining the prevalence of non-criteria anti-phospholipid antibodies in patients with anti-phospholipid syndrome: a systematic review., PMID:26152548
XTEN-annexin A5: XTEN allows complete expression of long-circulating protein-based imaging probes as recombinant alternative to PEGylation., PMID:24549285
[Annexins and recurrent pregnancy loss]., PMID:24152411
The haplotype M2 of the ANXA5 gene is not associated with antitrophoblast antibodies., PMID:23529182
The annexin A5 protective shield model revisited: inherited carriage of the M2/ANXA5 haplotype in placenta as a predisposing factor for the development of obstetric antiphospholipid antibodies., PMID:22635237
Surface plasmon resonance shows a gender difference in circulating annexin A5 in human., PMID:22483902
Annexin A5 binds to lipopolysaccharide and reduces its endotoxin activity., PMID:22415004
Circulating cell-derived microparticles in severe preeclampsia and in fetal growth restriction., PMID:21992597
Resistance to annexin A5 anticoagulant activity in women with histories for obstetric antiphospholipid syndrome., PMID:21784397
Prior exposure to oxidized low-density lipoprotein limits apoptosis in subsequent generations of endothelial cells by altering promoter methylation., PMID:21602467
Site-specific 68Ga-labeled Annexin A5 as a PET imaging agent for apoptosis., PMID:21492787
Multi-modal proteomic analysis of retinal protein expression alterations in a rat model of diabetic retinopathy., PMID:21249158
The annexin A5-mediated pathogenic mechanism in the antiphospholipid syndrome: role in pregnancy losses and thrombosis., PMID:20353989
Effects of anti-cardiolipin antibodies and IVIg on annexin A5 binding to endothelial cells: implications for cardiovascular disease., PMID:20132075
Anti-annexin A5 antibodies in women with spontaneous pregnancy loss., PMID:20022614
Hydroxychloroquine protects the annexin A5 anticoagulant shield from disruption by antiphospholipid antibodies: evidence for a novel effect for an old antimalarial drug., PMID:19965621
Both early and late apoptotic blebs are taken up by DC and induce IL-6 production., PMID:19811290
Gold fluorescent annexin A5 as a novel apoptosis detection tool., PMID:19437539
Resistance to annexin A5 anticoagulant activity: a thrombogenic mechanism for the antiphospholipid syndrome., PMID:18827057
Oxidized LDL, anti-oxidized LDL and anti-annexin A5 antibodies in primary antiphospholipid syndrome., PMID:18630740
Annexin A5 as a novel player in prevention of atherothrombosis in SLE and in the general population., PMID:17893975
Correlation between antiphospholipid antibodies that recognize domain I of beta2-glycoprotein I and a reduction in the anticoagulant activity of annexin A5., PMID:17053060
Antithrombotic action of annexin V proved as efficient as direct inhibition of tissue factor or thrombin., PMID:16919046
Annexin A5 binding to giant phospholipid vesicles is differentially affected by anti-beta2-glycoprotein I and anti-annexin A5 antibodies., PMID:16820381
Analysis of circulating annexin A5 parameters during pregnancy: absence of differences between women with recurrent spontaneous pregnancy losses and controls., PMID:16681990
Annexin A5 in cardiovascular disease and systemic lupus erythematosus., PMID:16325495
Antibodies against annexin A5: detection pitfalls and clinical associations., PMID:16278147
Cytokine modulation of liver annexin 1 expression during experimental endotoxemia., PMID:11583971
For research use only. Not for human or drug use.
