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Anti-MMP1 Antibody (R3A68)

Catalog #:   RHC04403 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM, IF, IHC
Accession: P03956
Overview

Catalog No.

RHC04403

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000

Target

MMP1, MMP-1, Matrix metalloproteinase-1, CLG, Interstitial collagenase, Fibroblast collagenase

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P03956

Applications

ELISA, FCM, IF, IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3A68

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Hela cells using MMP1 mouse mAb (green) and negative control (purple).
  • Immunofluorescence
    Immunofluorescence analysis of Hela cells using MMP1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues (left) and human kidney cancer tissues (right) using MMP1 mouse mAb with DAB staining.
References

Antiphospholipid antibodies inhibit the migration and invasion of trophoblast cells by suppressing the JNK/C-Jun/MMP1 signaling pathway., PMID:40410845

MMP1-induced NF-κB activation promotes epithelial-mesenchymal transition and sacituzumab govitecan resistance in hormone receptor-positive breast cancer., PMID:40287412

Exploration and Identification of Vitamin D and Related Genes as Potential Biomarkers for Colorectal Tumors., PMID:39872437

Effectiveness and cytokine profile of combined anti-vascular endothelial growth factor and corticosteroid therapy for chronic retinal vein occlusion., PMID:39825912

Perfluoroalkyl substances (PFAS) exposure and preeclampsia risk: Impaired angiogenesis through suppression of VEGF signaling., PMID:39732411

SPHK1 promotes HNSCC immune evasion by regulating the MMP1-PD-L1 axis., PMID:39629135

Airway proteomics reveals broad residual anti-inflammatory effects of prednisolone in mepolizumab-treated asthma., PMID:39097197

Identifying hub genes in response to ustekinumab and the impact of ustekinumab treatment on fibrosis in Crohn's disease., PMID:38840917

Tumor-matched and unmatched cancer associated fibroblasts exhibit differential effect on proliferation and FMOD and MMP9 gene expression in head and neck squamous cell carcinoma cells when cocultured in spheroids., PMID:38822309

A general approach for selection of epitope-directed binders to proteins., PMID:38683990

Characterization of immortalized ovarian epithelial cells with BRCA1/2 mutation., PMID:38615309

The Role of Matrix Metalloproteinases in Thoracic Aortic Disease: Are They Indicators for the Pathogenesis of Dissections?, PMID:38540232

An in vitro study elucidating the synergistic effects of aqueous cinnamon extract and an anti-TNF-α biotherapeutic: implications for a complementary and alternative therapy for non-responders., PMID:38521924

Protein kinase D drives the secretion of invasion mediators in triple-negative breast cancer cell lines., PMID:38323010

Immunoreactivity of p21, MMP-1 and CB2 receptor proteins in cutaneous canine mast cell tumours: an association with the three-tier grading system., PMID:38130452

Neuropeptide Y, a potential marker for lupus, promotes lupus development., PMID:38006754

Prediction of anti-TNF therapy failure in ulcerative colitis patients by ensemble machine learning: A prospective study., PMID:37928018

Granzyme B promotes matrix metalloproteinase-1 (MMP-1) release from gingival fibroblasts in a PAR1- and Erk1/2-dependent manner: A novel role in periodontal inflammation., PMID:37873693

Effect of chimeric antigen receptor T cells against protease-activated receptor 1 for treating pancreatic cancer., PMID:37667257

Paraneoplastic or not? Sirtuin 2 in anti-N-methyl-d-aspartate receptor encephalitis., PMID:37483157

Using Proteome Microarray and Gene Expression Omnibus Database to Screen Tumour-Associated Antigens to Construct the Optimal Diagnostic Model of Oesophageal Squamous Cell Carcinoma., PMID:37433700

A decrease of mitochondrial ubiquitin ligase increases the secretion of matrix metalloproteinase-1 by dermal fibroblasts through the induction of ER stress., PMID:37337400

Cytokinopathy with aberrant cytotoxic lymphocytes and profibrotic myeloid response in SARS-CoV-2 mRNA vaccine-associated myocarditis., PMID:37146127

Skeletonema marinoi Extracts and Associated Carotenoid Fucoxanthin Downregulate Pro-Angiogenic Mediators on Prostate Cancer and Endothelial Cells., PMID:37048126

Terminal Complement Activation Is Induced by Factors Released from Endplate Tissue of Disc Degeneration Patients and Stimulates Expression of Catabolic Enzymes in Annulus Fibrosus Cells., PMID:36980228

Mirikizumab Regulates Genes Involved in Ulcerative Colitis Disease Activity and Anti-TNF Resistance: Results From a Phase 2 Study., PMID:36881820

Role of Matrix Metalloproteinases and Their Inhibitors in Locally Invasive Papillary Thyroid Cancer., PMID:36551933

[Morphogenetic and pathogenetic features of hypertrophic and keloid scars of the head and neck]., PMID:36469714

Tofacitinib Inhibits STAT Phosphorylation and Matrix Metalloproteinase-3, -9 and -13 Production by C28/I2 Human Juvenile Chondrocytes., PMID:36217356

Diosmin and Trolox Have Anti-Arthritic, Anti-Inflammatory and Antioxidant Potencies in Complete Freund's Adjuvant-Induced Arthritic Male Wistar Rats: Roles of NF-κB, iNOS, Nrf2 and MMPs., PMID:36139795

Atorvastatin attenuates NS1 (Non-structural protein-1) of dengue type-2 serotype-induced expressions of matrix metalloproteinases in HL-60 cells, differentiated to neutrophils: Implications for the immunopathogenesis of dengue viral disease., PMID:36108401

Prenatal exposure to nickel and atopic dermatitis at age 3 years: a birth cohort study with cytokine profiles., PMID:35841308

Umbilicaria esculenta Extract Exhibits Antiwrinkle Activity by Suppressing ErbB2 Phosphorylation., PMID:35834632

Human organ rejuvenation by VEGF-A: Lessons from the skin., PMID:35749494

Gardnerella vaginalis induces matrix metalloproteinases in the cervicovaginal epithelium through TLR-2 activation., PMID:35679790

Concentration of Serum Matrix Metalloproteinase-3 in Patients With Primary Biliary Cholangitis., PMID:35529854

Autologous hematopoietic stem cell transplantation promotes connective tissue remodeling in systemic sclerosis patients., PMID:35488348

Mechanotransductive Mechanisms of Biomimetic Hydrogel Cues Modulating Meckel's Cartilage Degeneration., PMID:35347898

Inhibitory effect of membrane‑free stem cell components derived from adipose tissues on skin inflammation in keratinocytes., PMID:35169867

Oral Cancer Theranostic Application of FeAu Bimetallic Nanoparticles Conjugated with MMP-1 Antibody., PMID:35010011

Clinical value of serum biomarkers, squamous cell carcinoma antigen and apolipoprotein C-II in follow-up of patients with locally advanced cervical squamous cell carcinoma treated with radiation: A multicenter prospective cohort study., PMID:34727105

TNFα blockade reverses vascular and uteroplacental matrix metalloproteinases imbalance and collagen accumulation in hypertensive pregnant rats., PMID:34600915

A serological type II collagen neoepitope biomarker reflects cartilage breakdown in patients with osteoarthritis., PMID:36474766

Dihydromyricetin ameliorates liver fibrosis via inhibition of hepatic stellate cells by inducing autophagy and natural killer cell-mediated killing effect., PMID:34147124

Label-free electrochemical immunosensor based on gold nanoparticle/polyethyleneimine/reduced graphene oxide nanocomposites for the ultrasensitive detection of cancer biomarker matrix metalloproteinase-1., PMID:34048512

Adalimumab Induces a Wound Healing Profile in Patients with Hidradenitis Suppurativa by Regulating Macrophage Differentiation and Matrix Metalloproteinase Expression., PMID:33965402

Extensive cytokine analysis in synovial fluid of osteoarthritis patients., PMID:33895075

MIN score predicts primary response to infliximab/adalimumab and vedolizumab therapy in patients with inflammatory bowel diseases., PMID:33872704

Ablation of CRBN induces loss of type I collagen and SCH in mouse skin by fibroblast senescence via the p38 MAPK pathway., PMID:33658395

Matrix metalloproteinases in the pathogenesis of dengue viral disease: Involvement of immune system and newer therapeutic strategies., PMID:33634515

Datasheet

Document Download

Anti-MMP1 Antibody (R3A68).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-MMP1 Antibody (R3A68) [RHC04403]
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