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Anti-KRT18 Antibody (R2Z41)

Catalog #:   RHC17803 Specific References (34) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM, IF, IHC, WB
Accession: P05783
Overview

Catalog No.

RHC17803

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:500-1:2000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Target

Cytokeratin-18, CYK18, K18, Keratin, type I cytoskeletal 18, KRT18, CK-18, Keratin-18, Cell proliferation-inducing gene 46 protein

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P05783

Applications

ELISA, FCM, IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R2Z41

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Hela cells using KRT18 mouse mAb (green) and negative control (red).
  • Immunofluorescence
    Immunofluorescence analysis of Hela cells using KRT18 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissues using KRT18 mouse mAb with DAB staining.
References

Integrated analysis identifies the IL6/JAK/STAT signaling pathway and the estrogen response pathway associated with the pathogenesis of intracranial aneurysms., PMID:36451838

The K18-Human ACE2 Transgenic Mouse Model Recapitulates Non-severe and Severe COVID-19 in Response to an Infectious Dose of the SARS-CoV-2 Virus., PMID:34668775

Diagnostic and prognostic impact of cytokeratin 18 expression in human tumors: a tissue microarray study on 11,952 tumors., PMID:33588765

Antigen-agnostic microfluidics-based circulating tumor cell enrichment and downstream molecular characterization., PMID:33095819

Optimisation of a serum albumin removal protocol for use in a proteomic study to identify the protein biomarkers for silent gastric ulceration in horses., PMID:30250392

A mutation in keratin 18 that causes caspase-digestion resistance protects homozygous transgenic mice from hepatic apoptosis and injury., PMID:28606991

The bovine endometrial epithelial cells promote the differentiation of trophoblast stem-like cells to binucleate trophoblast cells., PMID:27473847

Study of CK18 and GDF5 immunoexpression in oral squamous cell carcinoma and their prognostic value., PMID:27151703

Molecular manipulation of keratin 8/18 intermediate filaments: modulators of FAS-mediated death signaling in human ovarian granulosa tumor cells., PMID:26911253

Characterization of swine testicular cell line as immature porcine Sertoli cell line., PMID:26744029

Correlation between serum cytokeratin-18 and the progression or regression of non-alcoholic fatty liver disease., PMID:26436355

Bacterial endotoxin and non-alcoholic fatty liver disease in the general population: a prospective cohort study., PMID:26202818

Oral cancer/endothelial cell fusion experiences nuclear fusion and acquisition of enhanced survival potential., PMID:25016285

Sensitivity and specificity of in situ proximity ligation for protein interaction analysis in a model of steatohepatitis with Mallory-Denk bodies., PMID:24798445

Subtle changes in surface chemistry affect embryoid body cell differentiation: lessons learnt from surface-bound amine density gradients., PMID:24354633

[Clinicopathologic features of papillary tumors of the pineal region]., PMID:23769439

The feasibility of sentinel lymph node biopsy for gastric cancer: the experience from Serbia., PMID:23613402

Evaluation of a replacement method for mammary gland biopsies by comparing gene expression in udder tissue and mammary epithelial cells isolated from milk., PMID:22265217

Activating transcription factor 3 and reactive astrocytes following optic nerve injury in zebrafish., PMID:21889613

Clinical and histopathological features and immunoreactivity of human choroidal and ciliary melanomas as prognostic factors for metastasis and death., PMID:21847577

Human hepatoma HepaRG cell line engraftment in severe combined immunodeficient × beige mice using mouse-specific anti-Fas antibody., PMID:21094855

Cytoskeletal keratin glycosylation protects epithelial tissue from injury., PMID:20729838

The application of artificial intelligence to microarray data: identification of a novel gene signature to identify bladder cancer progression., PMID:19913990

Immunohistochemical differential diagnosis between thymic carcinoma and type B3 thymoma: diagnostic utility of hypoxic marker, GLUT-1, in thymic epithelial neoplasms., PMID:19648882

Combinatory inhibition of VEGF and FGF2 is superior to solitary VEGF inhibition in an in vitro model of RPE-induced angiogenesis., PMID:19247683

Artificial intelligence and bladder cancer arrays., PMID:18314629

[Cytokeratin 18 and their gene expression in jaw odontogenic keratocyst epithelial lining]., PMID:17663325

Bispecific and human disease-related anti-keratin rabbit monoclonal antibodies., PMID:16343483

Keratins as susceptibility genes for end-stage liver disease., PMID:16143128

Identification of trichoplein, a novel keratin filament-binding protein., PMID:15731013

Cytokeratin 5/6 in normal human breast: lack of evidence for a stem cell phenotype., PMID:15376255

Keratin 8 and 18 hyperphosphorylation is a marker of progression of human liver disease., PMID:15368451

Morphological and immunohistochemical analysis of ductal plate malformation: correlation with fetal liver., PMID:15330804

Keratin 8/18 breakdown and reorganization during apoptosis., PMID:15194421

Datasheet

Document Download

Anti-KRT18 Antibody (R2Z41).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-KRT18 Antibody (R2Z41) [RHC17803]
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