Catalog No.
RHC17503
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, WB: 1:500-1:2000
Target
Transcription factor AP-2-alpha, AP-2 transcription factor, Activating enhancer-binding protein 2-alpha, TFAP2A, AP2-alpha, AP-2, Activator protein 2, TFAP2, AP2TF
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P05549
Applications
ELISA, FCM, IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2Z33
Tyrosine phosphorylation-mediated YAP1-TFAP2A interactions coordinate transcription and trastuzumab resistance in HER2+ breast cancer., PMID:38219531
Epigenetically modified AP-2α by DNA methyltransferase facilitates glioma immune evasion by upregulating PD-L1 expression., PMID:37330579
Integrated single-cell and bulk gene expression and ATAC-seq reveals heterogeneity and early changes in pathways associated with resistance to cetuximab in HNSCC-sensitive cell lines., PMID:32362655
Robust induction of neural crest cells to derive peripheral sensory neurons from human induced pluripotent stem cells., PMID:32152328
Heterodimerization of TFAP2 pioneer factors drives epigenomic remodeling during neural crest specification., PMID:31848212
Tissue organization alters gene expression in equine induced trophectoderm cells., PMID:28161437
Ascorbic acid uptaken by sodium-dependent vitamin C transporter 2 induces βhCG expression through Sp1 and TFAP2A transcription factors in human choriocarcinoma cells., PMID:22745243
Alternative TFAP2A isoforms have distinct activities in breast cancer., PMID:21375726
AP2 transcription factor induces apoptosis in retinoblastoma cells., PMID:20607706
AP-2alpha knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesis., PMID:20150232
Expression patterns of the transcription factor AP-2alpha during hair follicle morphogenesis and cycling., PMID:12839558
Pituitary tumor AP-2alpha recognizes a cryptic promoter in intron 4 of fibroblast growth factor receptor 4., PMID:12642581
Transcription of cholesterol side-chain cleavage cytochrome P450 in the placenta: activating protein-2 assumes the role of steroidogenic factor-1 by binding to an overlapping promoter element., PMID:12145340
Ap-2 and Ikaros regulate transcription of human placental leucine aminopeptidase/oxytocinase gene., PMID:11798181
Activator protein 2alpha transcription factor expression is associated with luminal differentiation and is lost in prostate cancer., PMID:11751506
Expression pattern of AP-2 transcription factors in cervical cancer cells and analysis of their influence on human papillomavirus oncogene transcription., PMID:11485026
Expression of transcription factor AP-2alpha predicts survival in epithelial ovarian cancer., PMID:10864206
Immunohistochemical analysis reveals a tumour suppressor-like role for the transcription factor AP-2 in invasive breast cancer., PMID:10629551
Keratin 10 gene expression during differentiation of mouse epidermis requires transcription factors C/EBP and AP-2., PMID:10588870
Differential expression of AP-2alpha and AP-2beta in the developing chick retina: repression of R-FABP promoter activity by AP-2., PMID:10090146
Tissue-specific in vivo protein-DNA interactions at the promoter region of the Xenopus 63 kDa keratin gene during metamorphosis., PMID:7501476
For research use only. Not for human or drug use.
