Catalog No.
RHC08301
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Applications
IHC
Recommended Dilution
| Application |
Dilution |
| IHC |
1:200-1:1000 |
Target
K1, KRT1, Type-II keratin Kb1, Hair alpha protein, Cytokeratin-1, Keratin-1, CK-1, KRTA, Keratin, type II cytoskeletal 1, 67 kDa cytokeratin
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P04264
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2Y71
Note
For research use only.
Keratin 12-deficient mice have fragile corneal epithelia., PMID:8977471
Cytokeratins 8 and 19 in the mouse placental development., PMID:11062258
Cis-regulatory elements of the mouse Krt1.12 gene., PMID:11951085
Inhibition of basement membrane formation by a nidogen-binding laminin gamma1-chain fragment in human skin-organotypic cocultures., PMID:15159456
Fluorescence-based methods for studying intermediate filaments., PMID:15646623
Early keratinocyte differentiation on micropillar interfaces., PMID:17297992
New concepts on the histogenesis of eccrine neoplasia from keratin expression in the normal eccrine gland, syringoma and poroma., PMID:18647305
Disturbed keratin expression and distinct genotype of ichthyosis hystrix Lambert type., PMID:20605767
MUC16 as a sensitive and specific marker for epithelial downgrowth., PMID:21060041
Mapping of a neutralizing epitope in the surface envelope protein of porcine endogenous retrovirus subgroup B., PMID:21228129
Tricholemmoma and clear cell squamous cell carcinoma (associated with Bowen's disease): immunohistochemical profile in comparison to normal hair follicles., PMID:22452951
Staphylococcus aureus inhibits terminal differentiation of normal human keratinocytes by stimulating interleukin-6 secretion., PMID:24398033
Keratin 1 plays a critical role in golgi localization of core 2 N-acetylglucosaminyltransferase M via interaction with its cytoplasmic tail., PMID:25605727
Analysis of Sera of Recipients with Allograft Rejection Indicates That Keratin 1 Is the Target of Anti-Endothelial Antibodies., PMID:28265584
Optimisation of a serum albumin removal protocol for use in a proteomic study to identify the protein biomarkers for silent gastric ulceration in horses., PMID:30250392
Functional study of 14-3-3 protein epsilon (YWHAE) in keratinocytes: microarray integrating bioinformatics approaches., PMID:31244373
Type XVIII Collagen Modulates Keratohyalin Granule Formation and Keratinization in Oral Mucosa., PMID:31554264
Arginine- but not alanine-rich carboxy-termini trigger nuclear translocation of mutant keratin 10 in ichthyosis with confetti., PMID:31638346
Post Zygotic, Somatic, Deletion in KERATIN 1 V1 Domain Generates Structural Alteration of the K1/K10 Dimer, Producing a Monolateral Palmar Epidermolytic Nevus., PMID:34199056
Gene expression profiling of laminin α3-blocked keratinocytes reveals an immune-independent mechanism of blistering., PMID:34796550
Study of pathological processes of meibomian gland dysfunction by in vitro culture airlifting conditions., PMID:37216482
Associations of serum keratin 1 with thyroid function and immunity in Graves' disease., PMID:38019813
Keratin 1 modulates intestinal barrier and immune response via kallikrein kinin system in ulcerative colitis., PMID:39958441
First successful treatment of epidermolytic Ichthyosis with Vunakizumab: A Case Report., PMID:40453098
For research use only. Not for human or drug use.
