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Anti-APOB Antibody (R2Y57)

Catalog #:   RHC06503 Specific References (49) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM, IF
Accession: P04114
Overview

Catalog No.

RHC06503

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000

Target

Apo B-48, Apo B-100, Apolipoprotein B-100, APOB

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P04114

Applications

ELISA, FCM, IF

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R2Y57

Data Image
  • Flow Cytometry
    Flow cytometric analysis of serun using ApoB mouse mAb (green) and negative control (purple).
  • Immunofluorescence
    Immunofluorescence analysis of HepG2 cells using ApoB mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
References

Robust Serum Proteomic Signatures of APOE2., PMID:40501769

An evaluation of recaticimab for the treatment of hypercholesterolemia., PMID:40380894

An ANGPTL4 inhibitory antibody safely improves lipid profiles in non-human primates., PMID:40360349

RNA interference versus antibody-based PCSK9 inhibition for the prevention of cardiovascular disease: A drug-target Mendelian randomization study., PMID:40347490

Tafolecimab, a Third Monoclonal Antibody for PCSK9 as the Novel Lipid-Lowering Drug Around the World: A Narrative Review., PMID:40167967

Analysis of non-cholesterol sterols and fatty acids in patients with graves' orbitopathy: insights into lipid metabolism in relation to the clinical phenotype of disease., PMID:40100571

Involvement of Fe(III) in the formation of immunoglobulin G-enriched protein aggregates in human plasma., PMID:40058718

Achieved levels of apolipoprotein B and plaque composition after acute coronary syndromes: Insights from HUYGENS., PMID:40020597

A Novel ELISA System for Measuring Modified LDL-Adiponectin Complex., PMID:39993736

Structure of apolipoprotein B100 bound to the low-density lipoprotein receptor., PMID:39663455

CDR identification, epitope mapping and binding affinity determination of novel monoclonal antibodies generated against human apolipoprotein B-100., PMID:39454741

Risk stratification analysis of recurrent myocardial infarction in Indian population using inflammatory, lipid, thrombotic and extracellular matrix remodeling markers., PMID:39351476

Spurious dyslipidemia due to paraprotein in a patient with Waldenström macroglobulinemia., PMID:39111648

Proteomic Analysis of Human Chylomicron Remnants Isolated by Apolipoprotein B-48 Immunoprecipitation., PMID:39085140

Advances in nucleic acid-targeted therapies for cardiovascular disease prevention., PMID:38970537

Coronary Artery Calcification Progression in Patients With Systemic Lupus Erythematosus., PMID:38950947

The role of serum lipid in predicting coronary artery lesions and intravenous immunoglobulin resistance in Kawasaki disease: a cohort study., PMID:38713460

Acoustic Delivery of Plasma Low-Density Lipoprotein into Liver via ApoB100-Targeted Microbubbles Inhibits Atherosclerotic Plaque Growth., PMID:38700017

Persistence and Adherence to PCSK9 Inhibitor Monoclonal Antibodies Versus Ezetimibe in Real-World Settings., PMID:38691317

Identification of apolipoprotein B-reactive CDR3 motifs allows tracking of atherosclerosis-related memory CD4+T cells in multiple donors., PMID:38571941

Proteomic Analysis of Egg Yolk Proteins During Embryonic Development in Wanxi White Goose., PMID:38433387

ANGPTL3 and ApoC-III inhibitors for treating hypertriglyceridemia in context: horses for courses?, PMID:38372218

Anti-Lipoprotein Lipase Antibody as a Useful Marker for Plaque Vulnerability in Patients with Stable Angina., PMID:38325861

New Advances in Rapid Pretreatment for Small Dense LDL Cholesterol Measurement Using Shear Horizontal Surface Acoustic Wave (SH-SAW) Technology., PMID:38256117

Genetic inhibition of angiopoietin-like protein-3, lipids, and cardiometabolic risk., PMID:38243829

Based on whole-exome sequencing to explore the rule of Herceptin and TKI resistance in breast cancer patients., PMID:38243282

A novel fully human anti-NT-ANGPTL3 antibody from phage display library exhibits potent ApoB, TG, and LDL-C lowering activities in hyperlipidemia mice., PMID:38174870

Lipid profile and NT-proBNP changes from pre-clinical to established rheumatoid arthritis: A 12 years follow-up explorative study., PMID:38161051

The analysis of serum lipids profile in Guillain-Barre syndrome., PMID:38143756

Stent composition and immune response after long-term coronary angioplasty., PMID:37934202

Evinacumab for Pediatric Patients With Homozygous Familial Hypercholesterolemia., PMID:37860863

Tafolecimab: First Approval., PMID:37847461

Effect of Intensive Lipid-Lowering Therapy on Coronary Plaque Stabilization Derived from Optical Coherence Tomography: a Meta-analysis and Meta-regression., PMID:37815648

New Biological Therapies for Low-Density Lipoprotein Cholesterol., PMID:37562541

Composition and distribution of lipoproteins after evolocumab in familial dysbetalipoproteinemia: A randomized controlled trial., PMID:37517914

Established and Emerging Lipid-Lowering Drugs for Primary and Secondary Cardiovascular Prevention., PMID:37486464

Establishment of a comprehensive diagnostic model for neuromyelitis optica spectrum disorders based on the analysis of laboratory indicators and clinical data., PMID:37191810

Metabolic profile in women with bulimia nervosa or binge-eating disorder before and after treatment: secondary analysis from the randomized PED-t trial., PMID:37103592

A Preliminary Study in Immune Response of BALB/c and C57BL/6 Mice with a Locally Allergic Rhinitis Model., PMID:36797980

Altered serum lipid levels are associated with prognosis of diffuse large B cell lymphoma and influenced by utility of rituximab., PMID:36670246

Effect of evolocumab on fasting and post fat load lipids and lipoproteins in familial dysbetalipoproteinemia., PMID:36384662

Lp(a), oxidized phospholipids and oxidation-specific epitopes are increased in subjects with keloid formation., PMID:36320028

Considerations for Use of Pharmacodynamic Biomarkers to Support Biosimilar Development - (I) A Randomized Trial with PCSK9 Inhibitors., PMID:36282186

PCSK9 is minimally associated with HDL but impairs the anti-atherosclerotic HDL effects on endothelial cell activation., PMID:36067830

[Serum Lipid Levels and Their Prognostic Significance in Patients with Multiple Myeloma]., PMID:35981378

Intervention of Shugan Xiaozhi Decoction on Nonalcoholic Fatty Liver Disease via Mediating Gut-Liver Axis., PMID:35837380

Apolipoprotein B, Residual Cardiovascular Risk After Acute Coronary Syndrome, and Effects of Alirocumab., PMID:35770629

The Progression of Treatment for Refractory Hypercholesterolemia: Focus on the Prospect of Gene Therapy., PMID:35754818

Circulating Autoantibodies Recognizing Immunodominant Epitopes From Human Apolipoprotein B Associate With Cardiometabolic Risk Factors, but Not With Atherosclerotic Disease., PMID:35479271

Datasheet

Document Download

Anti-APOB Antibody (R2Y57).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-APOB Antibody (R2Y57) [RHC06503]
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