Catalog No.
RHB77501
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, WB: 1:500-1:1000
Target
Protein sna, SNAI1, Zinc finger protein SNAI1, Protein snail homolog 1, SNAH
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O95863
Applications
ELISA, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2W46
Is epithelial-mesenchymal transition related to the biological behavior of salivary gland neoplasms?, PMID:38852529
Molecular Signatures in Swine Innate and Adaptive Immune Responses to African Swine Fever Virus Antigens p30/p54/CD2v Expressed Using a Highly Efficient Semliki Forest Virus Replicon System., PMID:37298266
Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease., PMID:36470928
IL11 stimulates ERK/P90RSK to inhibit LKB1/AMPK and activate mTOR initiating a mesenchymal program in stromal, epithelial, and cancer cells., PMID:35992082
SNAI1-expressing fibroblasts and derived-extracellular matrix as mediators of drug resistance in colorectal cancer patients., PMID:35878797
LATS kinases and SLUG regulate the transition to advanced stage in aggressive oral cancer cells., PMID:35859006
Immunohistochemical expression of E-cadherin, N-cadherin and Snail/slug in ameloblastoma., PMID:35659530
[Effect and mechanism of TNF-α and etanercept on the invasion ability of extravillous trophoblast cell in URSA patients]., PMID:34823320
Cellular junction and mesenchymal factors delineate an endometriosis-specific response of endometrial stromal cells to the mesothelium., PMID:34624439
COL10A1 is a novel factor in the development of choroidal neovascularization., PMID:34520774
Analysis of Several Pathways for Efficient Killing of Prostate Cancer Stem Cells: A Central Role of NF-κB RELA., PMID:34445612
PD-L1 tumor-intrinsic signaling and its therapeutic implication in triple-negative breast cancer., PMID:33884962
TGF-β activates pericytes via induction of the epithelial-to-mesenchymal transition protein SLUG in glioblastoma., PMID:33780024
Three and Four-Dimensional Visualization and Analysis Approaches to Study Vertebrate Axial Elongation and Segmentation., PMID:33720141
Radiation exposure triggers the malignancy of non‑small cell lung cancer cells through the activation of visfatin/Snail signaling., PMID:33432364
Molecular phenotypes of circulating tumor cells and efficacy of nivolumab treatment in patients with head and neck squamous cell carcinoma., PMID:33299117
RAC1B Regulation of TGFB1 Reveals an Unexpected Role of Autocrine TGFβ1 in the Suppression of Cell Motility., PMID:33260366
KIF3C Promotes Proliferation, Migration, and Invasion of Glioma Cells by Activating the PI3K/AKT Pathway and Inducing EMT., PMID:33150178
CBP-mediated Slug acetylation stabilizes Slug and promotes EMT and migration of breast cancer cells., PMID:32737855
Circular RNA circMET drives immunosuppression and anti-PD1 therapy resistance in hepatocellular carcinoma via the miR-30-5p/snail/DPP4 axis., PMID:32430013
LOXL2 upregulates hypoxia‑inducible factor‑1α signaling through Snail‑FBP1 axis in hepatocellular carcinoma cells., PMID:32323822
Robust induction of neural crest cells to derive peripheral sensory neurons from human induced pluripotent stem cells., PMID:32152328
Direct Extracellular NAMPT Involvement in Pulmonary Hypertension and Vascular Remodeling. Transcriptional Regulation by SOX and HIF-2α., PMID:32142369
SNAIL expression correlates with the translocation of syndecan‑1 intracellular domain into the nucleus in prostate cancer cell lines., PMID:32124938
SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis., PMID:31582836
C/EBPδ-Slug-Lox1 axis promotes metastasis of lung adenocarcinoma via oxLDL uptake., PMID:31562393
ANKHD1 is required for SMYD3 to promote tumor metastasis in hepatocellular carcinoma., PMID:30646949
Epithelial to Mesenchymal Transition in Human Mesothelial Cells Exposed to Asbestos Fibers: Role of TGF-β as Mediator of Malignant Mesothelioma Development or Metastasis via EMT Event., PMID:30609805
Annexin A1-suppressed autophagy promotes nasopharyngeal carcinoma cell invasion and metastasis by PI3K/AKT signaling activation., PMID:30459351
DSG2 Is a Functional Cell Surface Marker for Identification and Isolation of Human Pluripotent Stem Cells., PMID:29910125
CD47 is a direct target of SNAI1 and ZEB1 and its blockade activates the phagocytosis of breast cancer cells undergoing EMT., PMID:29632713
Role of Corneal Stromal Cells on Epithelial Cell Function during Wound Healing., PMID:29401709
Differential expression profiles of conserved Snail transcription factors in the mouse testis., PMID:29381885
The Interplay Between Epithelial-Mesenchymal Transition (EMT) and the Thyroid Hormones-αvβ3 Axis in Ovarian Cancer., PMID:29260382
Neutrophils and Snail Orchestrate the Establishment of a Pro-tumor Microenvironment in Lung Cancer., PMID:29241546
Expression of Epithelial-Mesenchymal Transition Regulating Transcription Factors in Head and Neck Squamous Cell Carcinomas., PMID:28982853
MDM2 promotes epithelial-mesenchymal transition and metastasis of ovarian cancer SKOV3 cells., PMID:28817834
Hybrid clone cells derived from human breast epithelial cells and human breast cancer cells exhibit properties of cancer stem/initiating cells., PMID:28768501
Nimotuzumab Inhibits Cholangiocarcinoma Cell Metastasis via Suppression of the Epithelial-Mesenchymal Transition Process., PMID:28668850
Poly I:C induces collective migration of HaCaT keratinocytes via IL-8., PMID:28438134
Snail acetylation by histone acetyltransferase p300 in lung cancer., PMID:28296173
Identification of Antibody Against SNRPB, Small Nuclear Ribonucleoprotein-Associated Proteins B and B', as an Autoantibody Marker in Crohn's Disease using an Immunoproteomics Approach., PMID:28204086
The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200., PMID:28197390
Differential expression of the epithelial mesenchymal transition factors Snail, Slug, Twist, TGF-β, and E-cadherin in ameloblastoma., PMID:27995335
Action of SNAIL1 in Cardiac Myofibroblasts Is Important for Cardiac Fibrosis following Hypoxic Injury., PMID:27706205
Multi-walled carbon nanotubes directly induce epithelial-mesenchymal transition in human bronchial epithelial cells via the TGF-β-mediated Akt/GSK-3β/SNAIL-1 signalling pathway., PMID:27251132
Targeting TYRO3 inhibits epithelial-mesenchymal transition and increases drug sensitivity in colon cancer., PMID:27132510
Gastrulation EMT Is Independent of P-Cadherin Downregulation., PMID:27097030
The histone variant H2A.X is a regulator of the epithelial-mesenchymal transition., PMID:26876487
Expression of the Long Non-Coding RNA HOTAIR Correlates with Disease Progression in Bladder Cancer and Is Contained in Bladder Cancer Patient Urinary Exosomes., PMID:26800519