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Anti-TNFRSF6B Antibody (R2W28)

Catalog #:   RHB64301 Specific References (31) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM
Accession: O95407
Overview

Catalog No.

RHB64301

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400

Target

Tumor necrosis factor receptor superfamily member 6B, Decoy receptor 3, Decoy receptor for Fas ligand, TNFRSF6B, DCR3, DcR3, TR6, M68

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O95407

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R2W28

Data Image
  • Flow Cytometry
    Flow cytometric analysis of HL-60 cells using TNFRSF6B mouse mAb (green) and negative control (red).
References

Identification of a costimulatory molecule-based signature for predicting prognosis risk and immunotherapy response in patients with lung adenocarcinoma., PMID:33457102

Association of Tumor Necrosis Like factor 1 A (TL1A) and its Decoy Receptor (DcR3) with The Disease Activity and Autoantibody Production in Rheumatoid Arthritis Patients., PMID:31332995

Decoy receptor 3 down-regulates centrosomal protein 70 kDa specifically in rheumatoid synovial fibroblasts., PMID:28696795

DcR3 promotes hepatoma cell migration by downregulating E-cadherin expression., PMID:28560426

Dendritic cells engineered to secrete anti-DcR3 antibody augment cytotoxic T lymphocyte response against pancreatic cancer in vitro., PMID:28223726

Serum decoy receptor 3 is a biomarker for disease severity in nonatopic asthma patients., PMID:26911723

Tumor Necrosis Factor-like Cytokine TL1A and Its Receptors DR3 and DcR3: Important New Factors in Mucosal Homeostasis and Inflammation., PMID:26099067

Effect of TNFRSF6B neutralization antibody on cell growth suppression and apoptosis induction in glioma cells., PMID:25997959

Absolute quantification of DcR3 and GDF15 from human serum by LC-ESI MS., PMID:25823874

Serum and synovial fluid levels of tumor necrosis factor-like ligand 1A and decoy receptor 3 in rheumatoid arthritis., PMID:25647275

Systemic and local expression levels of TNF-like ligand 1A and its decoy receptor 3 are increased in primary biliary cirrhosis., PMID:24016146

DcR3 induces cell proliferation through MAPK signaling in chondrocytes of osteoarthritis., PMID:21420502

Expression of DcR3 and its effects in kaposi's sarcoma-associated herpesvirus-infected human endothelial cells., PMID:21293109

Members 6B and 14 of the TNF receptor superfamily in multiple sclerosis predisposition., PMID:20962851

TNFRSF6B neutralization antibody inhibits proliferation and induces apoptosis in hepatocellular carcinoma cell., PMID:20591579

DcR3 protects THP-1 macrophages from apoptosis by increasing integrin alpha4., PMID:19748482

Ascites from epithelial ovarian cancer contain high levels of functional decoy receptor 3 (DcR3) and is associated with platinum resistance., PMID:18723214

DcR3 as a diagnostic parameter and risk factor for systemic lupus erythematosus., PMID:18562337

[Preparation and identification of monoclonal antibodies against human DcR3]., PMID:18237531

Apoptosis of dendritic cells induced by decoy receptor 3 (DcR3)., PMID:18006694

Evaluation of the novel serum markers B7-H4, Spondin 2, and DcR3 for diagnosis and early detection of ovarian cancer., PMID:17490732

Significant inhibition of human CD8(+) cytotoxic T lymphocyte-mediated xenocytotoxicity by overexpression of the human decoy Fas antigen., PMID:16534484

Prognostic impact of FAS/CD95/APO-1 in urothelial cancers: decreased expression of Fas is associated with disease progression., PMID:16091761

Soluble decoy receptor 3: increased levels in atopic patients., PMID:15282937

Soluble decoy receptor 3 induces angiogenesis by neutralization of TL1A, a cytokine belonging to tumor necrosis factor superfamily and exhibiting angiostatic action., PMID:14871847

Quantification and detection of DcR3, a decoy receptor in TNFR family., PMID:14871535

Rheumatoid arthritis synovial fluid macrophages express decreased tumor necrosis factor-related apoptosis-inducing ligand R2 and increased decoy receptor tumor necrosis factor-related apoptosis-inducing ligand R3., PMID:14613271

Endogenous decoy receptor 3 blocks the growth inhibition signals mediated by Fas ligand in human pancreatic adenocarcinoma., PMID:12794752

Mouse T cells receive costimulatory signals from LIGHT, a TNF family member., PMID:12384428

In vivo inhibition of Fas ligand-mediated killing by TR6, a Fas ligand decoy receptor., PMID:11408521

Fas-mediated apoptosis and expression of related genes in human malignant hematopoietic cells., PMID:11190279

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

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For research use only. Not for human or drug use.

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Anti-TNFRSF6B Antibody (R2W28) [RHB64301]
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