Catalog No.
RHB40701
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200, IP: 1:100-1:200, WB: 1:500-1:1000
Target
CGB-PDE, cGMP-specific 3',5'-cyclic phosphodiesterase, PDE5A, PDE5, cGMP-binding cGMP-specific phosphodiesterase
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O76074
Applications
IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2W03
Homogeneous single-label cGMP detection platform for the functional study of nitric oxide-sensitive (soluble) guanylyl cyclases and cGMP-specific phosphodiesterases., PMID:33060787
The role of PDE5a in oocyte maturation of zebrafish., PMID:31654676
Expression and distribution of phosphodiesterase isoenzymes in the human male urethra., PMID:25704994
Alterations in the interactome of serine/threonine protein phosphatase type-1 in atrial fibrillation patients., PMID:25593058
Defining the phosphodiesterase superfamily members in rat brain microvessels., PMID:22860158
Expression and distribution of phosphodiesterase isoenzymes in the human seminal vesicles., PMID:21810184
[Phoshodiesterases. The ''lords of the ring'' meet IgA nephropathy]., PMID:21132633
Neuronal nitric oxide synthase supports Renin release during sodium restriction through inhibition of phosphodiesterase 3., PMID:20651700
Immunohistochemical description of cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human labia minora., PMID:17498099
Immunohistochemical staining as a potential method for the identification of vaginal epithelial cells in forensic casework., PMID:17018095
Expression of cAMP and cGMP-phosphodiesterase isoenzymes 3, 4, and 5 in the human clitoris: immunohistochemical and molecular biology study., PMID:16635522
Immunohistochemical localisation of PDE5 in Leydig and myoid cells of prepuberal and adult rat testis., PMID:16163485
3',5'-cyclic nucleotide phosphodiesterase 11A: localization in human tissues., PMID:15800651
Phosphodiesterase 5 enzyme and its inhibitors: update on pharmacological and therapeutical aspects., PMID:15672122
Androgens regulate phosphodiesterase type 5 expression and functional activity in corpora cavernosa., PMID:14764637
The presence and function of phosphodiesterase type 5 in the rat myometrium., PMID:14749671
Individual cerebellar Purkinje cells express different cGMP phosphodiesterases (PDEs): in vivo phosphorylation of cGMP-specific PDE (PDE5) as an indicator of cGMP-dependent protein kinase (PKG) activation., PMID:12878685
Nitric oxide enhances angiogenesis via the synthesis of vascular endothelial growth factor and cGMP after stroke in the rat., PMID:12595343
PDE5 is converted to an activated state upon cGMP binding to the GAF A domain., PMID:12554648
CP248, a derivative of exisulind, causes growth inhibition, mitotic arrest, and abnormalities in microtubule polymerization in glioma cells., PMID:12477052
Type 5 phosphodiesterase expression in the human vagina., PMID:12100961
Regulation of cGMP-specific phosphodiesterase (PDE5) phosphorylation in smooth muscle cells., PMID:11723116
Expression of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in mouse tissues and cell lines using an antibody against the enzyme amino-terminal domain., PMID:11389965
Cross-regulation of intracellular cGMP and cAMP in cultured human corpus cavernosum smooth muscle cells., PMID:11152621
Immunohistochemical localization of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in rat tissues., PMID:10769052
Expression and regulation of the cGMP-binding, cGMP-specific phosphodiesterase (PDE5) in human colonic epithelial cells: role in the induction of cellular refractoriness to the heat-stable enterotoxin peptide., PMID:10679826
A cyclic nucleotide PDE5 inhibitor corrects defective mucin secretion in submandibular cells containing antibody directed against the cystic fibrosis transmembrane conductance regulator protein., PMID:10611481
For research use only. Not for human or drug use.
