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Anti-NCOR1 Antibody (R2V68)

Catalog #:   RHB17601 Specific References (22) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IHC
Accession: O75376
Overview

Catalog No.

RHB17601

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:200-1:1000

Target

Nuclear receptor corepressor 1, NCOR1, KIAA1047, N-CoR1, N-CoR

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O75376

Applications

IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R2V68

Data Image
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human cerebra (left) and breast carcinoma tissue (right), showing nuclear location with DAB staining using NCOR1 mouse mAb.
References

Autoimmune and neuropsychiatric phenotypes in a Mecp2 transgenic mouse model on C57BL/6 background., PMID:38524134

Multimodal molecular landscape of response to Y90-resin microsphere radioembolization followed by nivolumab for advanced hepatocellular carcinoma., PMID:37586766

NCOR1 may be a potential biomarker of a novel molecular subtype of prostate cancer., PMID:33058520

Macrophage NCOR1 Deficiency Ameliorates Myocardial Infarction and Neointimal Hyperplasia in Mice., PMID:32720575

SIRT1 induces the adipogenic differentiation of mouse embryonic stem cells by regulating RA-induced RAR expression via NCOR1 acetylation., PMID:32217463

Role of l-carnitine and oleate in myogenic differentiation: implications for myofiber regeneration., PMID:30149425

Epigenetic Regulation of the Blimp-1 Gene (Prdm1) in B Cells Involves Bach2 and Histone Deacetylase 3., PMID:26786103

Aberrant nuclear repressor coreceptor 1 localization in human retinoblastoma., PMID:23295231

Role of misfolded N-CoR mediated transcriptional deregulation of Flt3 in acute monocytic leukemia (AML)-M5 subtype., PMID:22514634

Improvement of sensitivity to tamoxifen in estrogen receptor-positive and Herceptin-resistant breast cancer cells., PMID:18768663

Direct association between the CREB-binding protein (CBP) and nuclear receptor corepressor (N-CoR)., PMID:17073437

Frequency and resistance of CD95 (Fas/Apo-1) gene-transfected tumor cells to CD95-mediated apoptosis by the elimination and methylation of integrated DNA., PMID:16506211

Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells., PMID:15531890

Repression of CAR-mediated transactivation of CYP2B genes by the orphan nuclear receptor, short heterodimer partner (SHP)., PMID:15000748

Expression of sex steroid receptors and their co-factors in normal and malignant breast tissue: AIB1 is a carcinoma-specific co-activator., PMID:12725419

Epstein-Barr virus nuclear antigen 3C recruits histone deacetylase activity and associates with the corepressors mSin3A and NCoR in human B-cell lines., PMID:12634383

Assembly of the SMRT-histone deacetylase 3 repression complex requires the TCP-1 ring complex., PMID:12502735

The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor., PMID:11641275

A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1., PMID:11013263

Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3., PMID:10944117

Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin., PMID:10441327

Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor., PMID:10049357

Datasheet

Document Download

Anti-NCOR1 Antibody (R2V68).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

Contact Information

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For research use only. Not for human or drug use.

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Anti-NCOR1 Antibody (R2V68) [RHB17601]
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