Catalog No.
RHB17601
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:200-1:1000
Target
Nuclear receptor corepressor 1, NCOR1, KIAA1047, N-CoR1, N-CoR
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O75376
Applications
IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2V68
Autoimmune and neuropsychiatric phenotypes in a Mecp2 transgenic mouse model on C57BL/6 background., PMID:38524134
Multimodal molecular landscape of response to Y90-resin microsphere radioembolization followed by nivolumab for advanced hepatocellular carcinoma., PMID:37586766
NCOR1 may be a potential biomarker of a novel molecular subtype of prostate cancer., PMID:33058520
Macrophage NCOR1 Deficiency Ameliorates Myocardial Infarction and Neointimal Hyperplasia in Mice., PMID:32720575
SIRT1 induces the adipogenic differentiation of mouse embryonic stem cells by regulating RA-induced RAR expression via NCOR1 acetylation., PMID:32217463
Role of l-carnitine and oleate in myogenic differentiation: implications for myofiber regeneration., PMID:30149425
Epigenetic Regulation of the Blimp-1 Gene (Prdm1) in B Cells Involves Bach2 and Histone Deacetylase 3., PMID:26786103
Aberrant nuclear repressor coreceptor 1 localization in human retinoblastoma., PMID:23295231
Role of misfolded N-CoR mediated transcriptional deregulation of Flt3 in acute monocytic leukemia (AML)-M5 subtype., PMID:22514634
Improvement of sensitivity to tamoxifen in estrogen receptor-positive and Herceptin-resistant breast cancer cells., PMID:18768663
Direct association between the CREB-binding protein (CBP) and nuclear receptor corepressor (N-CoR)., PMID:17073437
Frequency and resistance of CD95 (Fas/Apo-1) gene-transfected tumor cells to CD95-mediated apoptosis by the elimination and methylation of integrated DNA., PMID:16506211
Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells., PMID:15531890
Repression of CAR-mediated transactivation of CYP2B genes by the orphan nuclear receptor, short heterodimer partner (SHP)., PMID:15000748
Expression of sex steroid receptors and their co-factors in normal and malignant breast tissue: AIB1 is a carcinoma-specific co-activator., PMID:12725419
Epstein-Barr virus nuclear antigen 3C recruits histone deacetylase activity and associates with the corepressors mSin3A and NCoR in human B-cell lines., PMID:12634383
Assembly of the SMRT-histone deacetylase 3 repression complex requires the TCP-1 ring complex., PMID:12502735
The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor., PMID:11641275
A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1., PMID:11013263
Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3., PMID:10944117
Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin., PMID:10441327
Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor., PMID:10049357