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Anti-KDM4A Antibody (R2V57)

Catalog #:   RHB11507 Specific References (14) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IF, IHC
Accession: O75164
Overview

Catalog No.

RHB11507

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IF: 1:200-1:1000, IHC: 1:200-1:1000

Target

Lysine-specific demethylase 4A, JMJD2, Jumonji domain-containing protein 2A, KDM4A, KIAA0677, JHDM3A, [histone H3]-trimethyl-L-lysine(9) demethylase 4A, [histone H3]-trimethyl-L-lysine(36) demethylase 4A, JMJD2A, JmjC domain-containing histone demethylation protein 3A

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O75164

Applications

IF, IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R2V57

Data Image
  • Immunofluorescence
    Immunofluorescence analysis of NTERA-2 cells using KDM4A mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human colon cancer tissues (left) and human larynx cancer tissues (right) using KDM4A mouse mAb with DAB staining.
References

Comprehensive multiplexed autoantibody profiling of patients with advanced urothelial cancer., PMID:38309723

RETRACTED: KDM4A promotes the growth of non-small cell lung cancer by mediating the expression of Myc via DLX5 through the Wnt/β-catenin signaling pathway., PMID:33002480

RFX5 promotes the progression of hepatocellular carcinoma through transcriptional activation of KDM4A., PMID:32883983

Circ_SPECC1 enhances the inhibition of miR-526b on downstream KDM4A/YAP1 pathway to regulate the growth and invasion of gastric cancer cells., PMID:31349968

Novel inhibitors of lysine (K)-specific Demethylase 4A with anticancer activity., PMID:28905188

SUMO modification of a heterochromatin histone demethylase JMJD2A enables viral gene transactivation and viral replication., PMID:28212444

The Activity of JmjC Histone Lysine Demethylase KDM4A is Highly Sensitive to Oxygen Concentrations., PMID:28051298

Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy., PMID:27612013

Subsets of Visceral Adipose Tissue Nuclei with Distinct Levels of 5-Hydroxymethylcytosine., PMID:27171244

KDM4A, KDM4B and KDM4C in non-small cell lung cancer., PMID:26722485

Tetrazolylhydrazides as Selective Fragment-Like Inhibitors of the JumonjiC-Domain-Containing Histone Demethylase KDM4A., PMID:26337137

Small-molecule-based inhibition of histone demethylation in cells assessed by quantitative mass spectrometry., PMID:20583823

Diversity within the JMJD2 histone demethylase family., PMID:17207460

Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein., PMID:15927959

Datasheet

Document Download

Anti-KDM4A Antibody (R2V57).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-KDM4A Antibody (R2V57) [RHB11507]
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