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Anti-HIP1 Antibody (R2T36)

Catalog #:   RHA08102 Specific References (26) DATASHEET
Host species: Mouse
Isotype: IgG2a
Applications: IHC, IP, WB
Accession: O00291
Overview

Catalog No.

RHA08102

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a

Clonality

Monoclonal

Tested applications

IHC: 1:100-1:200, IP: 1:100-1:200, WB: 1:500-1:1000

Target

Huntingtin-interacting protein I, HIP-I, Huntingtin-interacting protein 1, HIP-1, HIP1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O00291

Applications

IHC, IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R2T36

Data Image
  • Immunohistochemical
    IHC-P analysis of kidney tissue by HIP1 antibody (RHA08102). IHC-P was performed using sections of the formalin-fixed paraffin-embedded kidney tissue;Result: Cells in tubules are positively stained at the cytoplasm.
  • Immunoprecipitation
    Lane 1: A549 lysate; Lane 2: HIP1 immunoprecipitated from A549 lysate by RHA08102;Lane 3: The same as Lane 2 but use IgG isotype control antibody;Result: RHA08102 can immunoprecipitate HIP1;
  • Western blot
    Lane 1: 15 µg of A549 lysate; Lane 2: 15 µg of HCT116 lysate; Lane 3: 15 µg of HEK-293 lysate;Lane 4: 15 µg of HeLa lysate; Result: RHA08102 can detect HIP1 by Western blotting.
References

Huntingtin-interacting protein 1 in cancer progression: a path less explored., PMID:40232352

Ocular Mucous Membrane Pemphigoid Demonstrates a Distinct Autoantibody Profile from Those of Other Autoimmune Blistering Diseases: A Preliminary Study., PMID:39584991

KIF1C and new Huntingtin-interacting protein 1 binding proteins regulate rheumatoid arthritis fibroblast-like synoviocytes' phenotypes., PMID:38726004

Mycobacterium tuberculosis impedes CD40-dependent notch signaling to restrict Th17 polarization during infection., PMID:35586066

Clinicopathological features and resistance mechanisms in HIP1-ALK-rearranged lung cancer: A multicenter study., PMID:34687488

Specific populations of urinary extracellular vesicles and proteins differentiate type 1 primary hyperoxaluria patients without and with nephrocalcinosis or kidney stones., PMID:33176829

Phenotypic characterisation of regulatory T cells in dogs reveals signature transcripts conserved in humans and mice., PMID:31530890

Custom Gene Capture and Next-Generation Sequencing to Resolve Discordant ALK Status by FISH and IHC in Lung Adenocarcinoma., PMID:27343444

Glycoprotein Ibα clustering induces macrophage-mediated platelet clearance in the liver., PMID:25231551

Huntingtin interacting protein 1 as a histopathologic adjunct in the diagnosis of Merkel cell carcinoma., PMID:25070010

Distinct c-Met activation mechanisms induce cell rounding or invasion through pathways involving integrins, RhoA and HIP1., PMID:24790222

Huntingtin-interacting protein 1: a Merkel cell carcinoma marker that interacts with c-Kit., PMID:21697888

BLOC1S2 interacts with the HIPPI protein and sensitizes NCH89 glioblastoma cells to apoptosis., PMID:18188704

Aberrant Huntingtin interacting protein 1 in lymphoid malignancies., PMID:17875735

Huntingtin interacting protein 1 is a novel brain tumor marker that associates with epidermal growth factor receptor., PMID:17440072

Serum antibodies to huntingtin interacting protein-1: a new blood test for prostate cancer., PMID:15899803

TMVA, a snake C-type lectin-like protein from Trimeresurus mucrosquamatus venom, activates platelet via GPIb., PMID:15501291

RNAi-mediated Hip1R silencing results in stable association between the endocytic machinery and the actin assembly machinery., PMID:14742709

HIP1 and HIP1r stabilize receptor tyrosine kinases and bind 3-phosphoinositides via epsin N-terminal homology domains., PMID:14732715

Bifunctional apoptosis inhibitor (BAR) protects neurons from diverse cell death pathways., PMID:14502241

Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking., PMID:12839988

Huntingtin-interacting protein-1-related protein of rat (rHIP1R) is localized in the postsynaptic regions., PMID:12650982

A novel polymorphism, 70Leu/Phe, disrupts a consensus Leu residue within the leucine-rich repeat sequence of platelet glycoprotein Ibalpha., PMID:12038791

Influence of monoclonal antiplatelet glycoprotein antibodies on in vitro human megakaryocyte colony formation and proplatelet formation., PMID:10068668

HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system., PMID:9147654

The HIP1 initiator element plays a role in determining the in vitro requirement of the dihydrofolate reductase gene promoter for the C-terminal domain of RNA polymerase II., PMID:1569952

Datasheet

Document Download

Anti-HIP1 Antibody (R2T36).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-HIP1 Antibody (R2T36) [RHA08102]
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