Catalog No.
SHC12503
Species
Human
Protein length
DAEFRHDSGYEVHHQKC
Nature
Synthetic peptide
Purity
>90% as determined by HPLC.
Accession
P05067
Form
Lyophilized
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Aβ 1-16, β-Amyloid (1-16) Peptide, Abeta 1-16, Beta-APP 1-16, Amyloid-beta protein 1-16, amyloid beta A4 precursor protein, Amyloid-beta A4 protein
Investigating the combined effect of copper, zinc, and iron ions on truncated and full-length Aβ peptides: insights from molecular dynamics simulation., PMID:38189361
Modulating innate immune activation states impacts the efficacy of specific Aβ immunotherapy., PMID:33957936
Aβ1-16 controls synaptic vesicle pools at excitatory synapses via cholinergic modulation of synapsin phosphorylation., PMID:33864480
Emodin inhibits aggregation of amyloid-β peptide 1-42 and improves cognitive deficits in Alzheimer's disease transgenic mice., PMID:32799401
Copper(II) partially protects three histidine residues and the N-terminus of amyloid-β peptide from diethyl pyrocarbonate (DEPC) modification., PMID:32255544
Ubiquitin binds the amyloid β peptide and interferes with its clearance pathways., PMID:30996991
Transition metal-coordinated graphitic carbon nitride dots as a sensitive and facile fluorescent probe for β-amyloid peptide detection., PMID:30474660
Fluorescent Copper Probe Inhibiting Aβ1-16-Copper(II)-Catalyzed Intracellular Reactive Oxygen Species Production., PMID:28318262
Maysin and Its Flavonoid Derivative from Centipedegrass Attenuates Amyloid Plaques by Inducting Humoral Immune Response with Th2 Skewed Cytokine Response in the Tg (APPswe, PS1dE9) Alzheimer's Mouse Model., PMID:28072821
Copper Exchange and Redox Activity of a Prototypical 8-Hydroxyquinoline: Implications for Therapeutic Chelation., PMID:27409140
Resistance of Cu(Aβ4-16) to Copper Capture by Metallothionein-3 Supports a Function for the Aβ4-42 Peptide as a Synaptic Cu(II) Scavenger., PMID:27238224
On the ability of CuAβ1-x peptides to form ternary complexes: Neurotransmitter glutamate is a competitor while not a ternary partner., PMID:26970944
Molecular Simulations of Human and Mouse Aβ1-16 at Different pH Values: Structural Characteristics toward Understanding Cu(2+) -Coordinated Amyloid Beta Spheres., PMID:26928943
Intracerebral Injection of Metal-Binding Domain of Aβ Comprising the Isomerized Asp7 Increases the Amyloid Burden in Transgenic Mice., PMID:26842600
Histidine availability is decisive in ROS-mediated cytotoxicity of copper complexes of Aβ1-16 peptide., PMID:26690929
Zinc-induced heterodimer formation between metal-binding domains of intact and naturally modified amyloid-beta species: implication to amyloid seeding in Alzheimer's disease?, PMID:26513486
Transfer of Copper from an Amyloid to a Natural Copper-Carrier Peptide with a Specific Mediating Ligand., PMID:26420347
The Na+/K+-ATPase and the amyloid-beta peptide aβ1-40 control the cellular distribution, abundance and activity of TRPC6 channels., PMID:26348127
Development of gold nanoparticle based colorimetric method for quantitatively studying the inhibitors of Cu(2+)/Zn(2+) induced β-amyloid peptide assembly., PMID:25597800
Nanopore investigation of the stereoselective interactions between Cu(2+) and D,L-histidine amino acids engineered into an amyloidic fragment analogue., PMID:25479713
Cisplatin inhibits the formation of a reactive intermediate during copper-catalyzed oxidation of amyloid β peptide., PMID:25237806
Key roles of Arg(5), Tyr(10) and his residues in Aβ-heme peroxidase: relevance to Alzheimer's disease., PMID:25193696
Effects of oxidation on redox and cytotoxic properties of copper complex of Aβ1-16 peptide., PMID:25179438
Characterization of the enhanced peroxidatic activity of amyloid β peptide-hemin complexes towards neurotransmitters., PMID:24760399
Probing of various physiologically relevant metals-amyloid-β peptide interactions with a lipid membrane-immobilized protein nanopore [corrected]., PMID:24715156
Effect of C-terminal residues of Aβ on copper binding affinity, structural conversion and aggregation., PMID:24594588
Investigation of Cu2+ binding to human and rat amyloid fragments Aβ (1-16) with a protein nanopore., PMID:24274576
Effects of oxidation on copper-binding properties of Aβ1-16 peptide: a pulse radiolysis study., PMID:24074186
A micro-environmental study of the Zn(+2)-Aβ1-16 structural properties., PMID:23932412
[Identification of the minimal zinc-binding center in natural isoforms of amyloid-beta domain 1-16 using ESI-MS]., PMID:23888782
Longitudinal amyloid imaging in mouse brain with 11C-PIB: comparison of APP23, Tg2576, and APPswe-PS1dE9 mouse models of Alzheimer disease., PMID:23833271
PtCl2(phen) disrupts the metal ions binding to amyloid-β peptide., PMID:23689733
Structural studies of the tethered N-terminus of the Alzheimer's disease amyloid-β peptide., PMID:23609990
Biochemical identification of a linear cholesterol-binding domain within Alzheimer's β amyloid peptide., PMID:23509984
α-secretase cleaved amyloid precursor protein (APP) accumulates in cholinergic dystrophic neurites in normal, aged hippocampus., PMID:23414335
Aβ1-15/16 as a potential diagnostic marker in neurodegenerative diseases., PMID:23225274
Nitric oxide-mediated regulation of β-amyloid clearance via alterations of MMP-9/TIMP-1., PMID:23016931
Amyloid-β metabolism in Niemann-Pick C disease models and patients., PMID:22935999
Mass spectral studies reveal the structure of Aβ1-16-Cu2+ complex resembling ATCUN motif., PMID:22804558
Thermodynamic analysis of the molecular interactions between amyloid β-protein fragments and (-)-epigallocatechin-3-gallate., PMID:22536844
Evaluation of the performance of novel Aβ isoforms as theragnostic markers in Alzheimer's disease: from the cell to the patient., PMID:22302034
Aβ1-16 can aggregate and induce the production of reactive oxygen species, nitric oxide, and inflammatory cytokines., PMID:21860093
Vitamin A has anti-oligomerization effects on amyloid-β in vitro., PMID:21811022
Novel aβ isoforms in Alzheimer's disease - their role in diagnosis and treatment., PMID:21728980
Cerebral amyloid angiopathy in streptozotocin rat model of sporadic Alzheimer's disease: a long-term follow up study., PMID:21533606
Characterization of the brain β-amyloid isoform pattern at different ages of Tg2576 mice., PMID:21346320
Alzheimer's Aβ peptides with disease-associated N-terminal modifications: influence of isomerisation, truncation and mutation on Cu2+ coordination., PMID:21209855
A novel Abeta isoform pattern in CSF reflects gamma-secretase inhibition in Alzheimer disease., PMID:20350302
Gold nanoparticle-based colorimetric sensor for studying the interactions of beta-amyloid peptide with metallic ions., PMID:20152387
Distinct cerebrospinal fluid amyloid beta peptide signatures in sporadic and PSEN1 A431E-associated familial Alzheimer's disease., PMID:20145736
For research use only. Not for human or drug use.
