Catalog No.
SHC12502
Species
Human
Protein length
GSNKGAIIGLM
Nature
Synthetic peptide
Purity
>90% as determined by HPLC.
Accession
P05067
Form
Lyophilized
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Aβ 25-35, β-Amyloid (25-35) Peptide, Abeta (25-35), Beta-APP (25-35), Amyloid-beta protein (25-35), amyloid beta A4 precursor protein, Amyloid-beta A4 protein
Can linc00968 Regulate SH-SY5Y Cell Apoptosis Induced by Amyloid beta Neurotoxicity?, PMID:40478272
Celastrol attenuates Alzheimer's disease-mediated learning and memory impairment by inhibiting endoplasmic reticulum stress-induced inflammation and oxidative stress., PMID:40395889
Silencing of lncRNA PRR34-AS1 Alleviates Alzheimer's Disease by Targeting miR-29c-3p to Regulate Microglia Inflammation., PMID:40355341
Study on the mechanism of Xanthoceras sorbifolia Bunge oil in the treatment of Alzheimer's disease by an integrated "network pharmacology-metabolomics" strategy., PMID:40340504
Oroxylum indicum (L.) Leaf Extract Attenuates β-Amyloid-Induced Neurotoxicity in SH-SY5Y Cells., PMID:40243521
Melatonin protects mouse hippocampal neurons from neurotoxicity induced by amyloid β-peptide25-35., PMID:40222698
Effect of osmolytes on the conformational stability of Aβ(25-35): A circular dichroism analysis., PMID:40187472
Protection of dauricine and daurisoline on PC12 cells damaged by glutamate or Aβ25-35., PMID:40185223
Gastrodin alleviates Aβ25-35-induced glycolytic dysfunction via activating PI3K/AKT/BACH1 signaling in Alzheimer's disease models., PMID:40127855
Aloe-Emodin Improves Mitophagy in Alzheimer's Disease via Activating the AMPK/PGC-1α/SIRT3 Signaling Pathway., PMID:40125832
The Use of Natural Volatile Compounds on the Fibrillation Domain of Amyloid Beta (GSNKGAIIGLM)─Towards Promising Agents to Combat Alzheimer's Disease., PMID:40059298
Ferulago angulata Extract Protects against Beta-amyloid-induced Memory Impairment Through Modulation of Monoaminoxidase Enzymes in the Rat's Hippocampus., PMID:40042687
Exploring the Mechanism of Kai-Xin-San to Improve Cognitive Deficits in AD Rats Induced by D-Gal and Aβ25-35 Based on Multi-Omics and Network Analysis., PMID:40033867
Astragalin actives autophagy and inhibits apoptosis of astrocytes in AD mice via down-regulating Fas/Fasl-VDAC1 pathway., PMID:40032030
Diketopiperazine and purine alkaloids from the tubers of Pinellia pedatisecta Schott and their protective activities against Aβ25-35-induced PC-12 cell injury., PMID:39983940
Impact of Amidation on Aβ25-35 Aggregation., PMID:39945395
[Kaixin San-medicated serum attenuates Aβ_(25-35)-induced injury in SH-SY5Y cells by regulating autophagy]., PMID:39929613
Longan Aril polysaccharides ameliorate cognitive impairment in AD mice via restoration of the immune phagocytosis of microglia., PMID:39923958
Involvement of CRMP2 Phosphorylation in Amyloid Beta-induced Tau Phosphorylation of Hippocampal Neurons in Alzheimer's Disease Mouse Model., PMID:39891817
Neuroprotection by chronic administration of Fluoroethylnormemantine (FENM) in mouse models of Alzheimer's disease., PMID:39762936
Ganoderic acid a alleviates Aβ25-35-induced HT22 cell apoptosis through the ERK/MAPK pathway: a system pharmacology and in vitro experimental validation., PMID:39625499
Walnut-derived peptides cross the blood-brain barrier and ameliorate Aβ-induced hypersynchronous neural network activity., PMID:39577950
Understanding Aβ25-35 peptide altered exosomal proteome and associated pathways linked with the Alzheimer's disease pathogenesis using human neuroblastoma SH-SY5Y Cells., PMID:39565424
Alkaloids with Their Protective Effects Against Aβ25-35-Induced PC-12 Cell Injury from the Tubers of Pinellia pedatisecta Schott., PMID:39519701
Efficacy and Mechanism of Schisandra chinensis Fructus Water Extract in Alzheimer's Disease: Insights from Network Pharmacology and Validation in an Amyloid-β Infused Animal Model., PMID:39519586
[Possibility of short synthetic peptides with activities of suppressing amyloid β aggregation and resolving its aggregated form as therapeutic drugs for Alzheimer's disease]., PMID:39496417
[Effects of JAL-TA9 on cognitive deficits in Alzheimer's disease model mouse]., PMID:39496415
Preventive effects of coixol, an active compound of adlay seed, in NGF-differentiated PC12 cells against beta-amyloid25-35-induced neurotoxicity., PMID:39483714
Effect of the aggregation state of amyloid-beta (25-35) on the brain oxidative stress in vivo., PMID:39471144
An 11-mer Synthetic Peptide Suppressing Aggregation of Aβ25-35 and Resolving Its Aggregated Form Improves Test Performance in an Aβ25-35-Induced Alzheimer's Mouse Model., PMID:39456166
Mica Lattice Orientation of Epitaxially Grown Amyloid β25-35 Fibrils., PMID:39408788
Schisandrin A Alleviates Inflammation and Oxidative Stress in Aβ25-35-Induced Alzheimer's Disease in Vitro Model., PMID:39403912
Neobavaisoflavone Ameliorates Memory Deficits and Brain Damage in Aβ25-35-Induced Mice by Regulating SIRT1., PMID:39392360
Aβ25-35-induced autophagy and apoptosis are prevented by the CRMP2-derived peptide ST2-104 (R9-CBD3) via a CaMKKβ/AMPK/mTOR signaling hub., PMID:39325788
Protein Kinase C-Delta Mediates Cell Cycle Reentry and Apoptosis Induced by Amyloid-Beta Peptide in Post-Mitotic Cortical Neurons., PMID:39273571
Interplay of MeCP2/REST/Synaptophysin-BDNF and intranasal oxytocin influence on Aβ-induced memory and cognitive impairments., PMID:39236931
Identification of the Shared Gene Signatures Between Alzheimer's Disease and Diabetes-Associated Cognitive Dysfunction by Bioinformatics Analysis Combined with Biological Experiment., PMID:39213070
Chloride intracellular channel 4 blockade improves cognition in mice with Alzheimer's disease: CLIC4 protein expression and tau protein hyperphosphorylation., PMID:39181373
Neuroprotective effects of resveratrol through modulation of PI3K/Akt/GSK-3β pathway and metalloproteases., PMID:39159067
Activation of multifunctional DNA repair APE1/Ref-1 enzyme by the dietary phytochemical Ferulic acid protects human neuroblastoma SH-SY5Y cells against Aβ(25-35)-induced oxidative stress and inflammatory responses., PMID:39151817
Ginkgo biloba extract inhibits hippocampal neuronal injury caused by mitochondrial oxidative stress in a rat model of Alzheimer's disease., PMID:39106233
Diosmin ameliorates inflammation, apoptosis and activates PI3K/AKT pathway in Alzheimer's disease rats., PMID:39105973
Calcium ions do not influence the Aβ(25-35) triggered morphological changes of lipid membranes., PMID:39018778
Polysaccharides from Basella alba Protect Post-Mitotic Neurons against Cell Cycle Re-Entry and Apoptosis Induced by the Amyloid-Beta Peptide by Blocking Sonic Hedgehog Expression., PMID:39000427
Thioredoxin-1 Protects Neurons Through Inhibiting NLRP1-Mediated Neuronal Pyroptosis in Models of Alzheimer's Disease., PMID:38976128
Cannabidiol protects mouse hippocampal neurons from neurotoxicity induced by amyloid β-peptide25-35., PMID:38901785
Reduction in Hippocampal Amyloid-β Peptide (Aβ) Content during Glycine-Proline-Glutamate (Gly-Pro-Glu) Co-Administration Is Associated with Changes in Inflammation and Insulin-like Growth Factor (IGF)-I Signaling., PMID:38891902
The selective butyrylcholinesterase inhibitor UW-MD-95 shows symptomatic and neuroprotective effects in a pharmacological mouse model of Alzheimer's disease., PMID:38887858
Neuroprotective effect of emodin on Aβ25-35-induced cytotoxicity in PC12 cells involves Nrf2/GPX4 and TLR4/p-NF-κB/NLRP3 pathways., PMID:38795791
Crocin ameliorates neuroinflammation and cognitive impairment in mice with Alzheimer's disease by activating PI3K/AKT pathway., PMID:38775292
For research use only. Not for human or drug use.
