Aβ1-42/β-Amyloid (1-42) Peptide, Human

Catalog No.

SHK08201

Species

Human

Protein length

DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

Predicted molecular weight

4.5 kDa

Nature

Synthetic peptide

Purity

>90% as determined by HPLC.

Accession

P05067, CAS: 107761-42-2

Form

Lyophilized

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Aβ 1-42, β-Amyloid (1-42) Peptide, Abeta42, Beta-APP42, Amyloid-beta protein 42, amyloid beta A4 precursor protein, Amyloid-beta A4 protein

Alpha-synuclein co-pathology in Down syndrome-associated Alzheimer's disease., PMID:40528443

Dantrolene Protects Hippocampal Neurons Against Amyloid-β₁₋₄₂-Induced Calcium Dysregulation and Cell Death., PMID:40504441

Avenanthramide-C as Alzheimer's Disease-Modifying Therapy: Early and Sustained Intervention Prevents Disease Progression in Mouse Models., PMID:40498003

Association of Plasma Phosphorylated Tau 217 With Clinical Deterioration Across Alzheimer Disease Stages., PMID:40472304

[Cerebrospinal Fluid Biomarker Profile in Atypical Alzheimer's Disease]., PMID:40464420

Potential role of Amyloid-β on the association between Orexin-A and blood-brain barrier leakage of globus pallidus in Alzheimer's disease and dementia with lewy bodies., PMID:40457423

Neuroprotective Effects of Tectoridin in H2O2-Induced Oxidative Stress and an Amyloid-Infused Rat Model of Alzheimer's Disease., PMID:40455354

Chimeric antigen receptors discriminate between tau and distinct amyloid-beta species., PMID:40448101

Hancinone possesses potentials on increasing the ability of HMC3 cells to phagocytosis of Aβ1-42 via TREM2/Syk/PI3K/AKT/mTOR signaling pathway., PMID:40424233

Cerebrospinal Fluid Biomarkers and Cognition in Alzheimer Disease and Frontotemporal Dementia in a Memory Clinic Setting., PMID:40397510

Mass-Spectrometry-Based GEE Footprinting Characterizes Kinetic Mechanisms and Sites of Conformational Change in Amyloid β 1-42 Aggregation., PMID:40378310

Peptides of corn oligopeptides improve Aβ1-42-injured SHSY5Y cells., PMID:40375668

Effects of Solvent Dimethyl Sulfoxide Invites a Rethink of Its Application in Amyloid Beta Cytotoxicity., PMID:40373217

Overexpression of LINC00672 promotes autophagy in Alzheimer's disease by upregulating GPNMB., PMID:40367036

Method comparison and re-calibration of three top-used immunoassays and one LC-MS/MS assay for four core cerebrospinal fluid biomarkers of Alzheimer's disease: an explorative study for harmonization., PMID:40360016

Neurotoxic amyloid β-peptide and tau produce cytokine-like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression., PMID:40325855

Cognitive improvement effects of PF-04957325, a phosphodiesterase-8 inhibitor, in mouse models of Alzheimer's disease via modulating neuroinflammation., PMID:40312965

Biomarkers in Alzheimer's disease: new frontiers with olfactory models., PMID:40312605

Cerebrospinal Fluid Biomarkers for Alzheimer Disease Among Patients With Dementia., PMID:40293734

Italian Biodiversity: A Source of Edible Plant Extracts with Protective Effects Against Advanced Glycation End Product-Related Diseases., PMID:40289949

A 3D human iPSC-derived multi-cell type neurosphere system to model cellular responses to chronic amyloidosis., PMID:40275379

Investigating the relationship between sleep disturbances and cortical thickness, brainstem volume, amyloid accumulation, and inflammatory markers in Parkinson's disease patients., PMID:40252714

Tangeretin protects against Aβ1-42-induced toxicity and exploring mitochondria-lysosome interactions in HT22 cells., PMID:40220719

Loss of age-accumulated crh-1 circRNAs ameliorate amyloid β-induced toxicity in a C. elegans model for Alzheimer's disease., PMID:40196178

Heterophyllin B alleviates cognitive disorders in APP/PS1 model mice via the spleen-gut microbiota-brain axis., PMID:40194455

Naturido alleviates amyloid β1-42-induced adverse effects in a transgenic Caenorhabditis elegans model of Alzheimer's disease., PMID:40138382

Etomidate ameliorates Alzheimer-like neuropathology and cognitive impairment in APP/PS1 mice., PMID:40137847

Potential of facial biomarkers for Alzheimer's disease and obstructive sleep apnea in Down syndrome and general population., PMID:40123509

Blood biomarkers differentiate AD-related versus non-AD-related cognitive deficits., PMID:40110626

Cordycepin mediates neuroprotection against apoptosis via ERK/CREB signaling activation in Aβ1-42-induced neuronal cell models., PMID:40103703

Exosomes derived from olfactory mucosa mesenchymal stem cells attenuate cognitive impairment in a mouse model of Alzheimer's disease., PMID:40101983

Multi-functional memantine nitrate attenuated cognitive impairment in models of vascular dementia and Alzheimer's disease through neuroprotection and increased cerebral blood flow., PMID:40081796

Comparing In vitro Protein Aggregation Modelling Using Strategies Relevant to Neuropathologies., PMID:40080205

Explore peptides extracted from gliadin hydrolysates suppressing BACE1 activity and restraining Aβ protein deposition., PMID:40074130

Kaempferia parviflora extract and its methoxyflavones as potential anti-Alzheimer assessing in vitro, integrated computational approach, and in vivo impact on behaviour in scopolamine-induced amnesic mice., PMID:40063637

L1CAM mimetic compound duloxetine improves cognitive impairment in 5xFAD mice and protects Aβ1-42-damaged HT22 cells., PMID:40057157

Diagnostic and Prognostic Biomarkers of Idiopathic Normal Pressure Hydrocephalus in Cerebrospinal Fluid and Blood., PMID:40054974

Cerium-doped Prussian blue biomimetic nanozyme as an amplified pyroptosis inhibitor mitigate Aβ oligomer-induced neurotoxicity in Alzheimer's disease., PMID:40050873

Overlapping presence of β-amyloid, tau, p-tau, and α-synuclein in skin nerve fibers in Alzheimer's disease., PMID:40042672

Effect of knockdown LncRNA SNHG1 on autophagic function in SH-SY5Y cells: a model of Alzheimer's disease (AD)., PMID:40042509

Astragalin actives autophagy and inhibits apoptosis of astrocytes in AD mice via down-regulating Fas/Fasl-VDAC1 pathway., PMID:40032030

Synthesis and Characterization of Memantine-Loaded Niosomes for Enhanced Alzheimer's Disease Targeting., PMID:40006634

Ganaxolone Reverses the Effect of Amyloid β-Induced Neurotoxicity by Regulating the Liver X Receptor Expression in APP Transfected SH-SY5Y Cells and Murine Model of Alzheimer's Disease., PMID:39936324

[The experience of diagnosing Alzheimer's disease based on the study of cerebrospinal fluid biomarkers]., PMID:39930682

MK886 ameliorates Alzheimer's disease by activating the PRKCI/AKT signaling pathway., PMID:39922422

Anticholinergic drugs and dementia risk: Using stem cell-based studies to complement pharmacoepidemiology., PMID:39911736

Amyloid-β can activate JNK signalling via WNT5A-ROR2 to reduce synapse formation in Alzheimer's disease., PMID:39907042

The effect of Lewy body (co-)pathology on the clinical and imaging phenotype of amnestic patients., PMID:39888600

Plasma p-tau217 and p-tau217/Aβ1-42 are effective biomarkers for identifying CSF- and PET imaging-diagnosed Alzheimer's disease: Insights for research and clinical practice., PMID:39887504

Programmable short peptides for modulating stem cell fate in tissue engineering and regenerative medicine., PMID:39871657

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