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Recombinant Human IL2 Superkine (Mutant) Protein, C-His (Active)

Catalog #:   AHF36804 Specific References (50) DATASHEET
Applications: Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Expression system: Mammalian Cells
Accession: P60568
Protein length: Ala21-Thr153 (L100F, R101D, L105V, I106V, I112F)
Overview

Catalog No.

AHF36804

Expression system

Mammalian Cells

Species

Homo sapiens (Human)

Protein length

Ala21-Thr153 (L100F, R101D, L105V, I106V, I112F)

Predicted molecular weight

16.5 kDa

Nature

Recombinant

Endotoxin level

< 1 EU/µg as determined by LAL test.

Purity

>90% as determined by SDS-PAGE.

Accession

P60568

Applications

Bioactivity, ELISA, Immunogen, SDS-PAGE, WB

Form

Lyophilized

Storage buffer

Lyophilized from a 0.2 μm filtered solution in 4 mM HCl.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

IL2, IL-2, Aldesleukin, Interleukin-2, TCGF, T-cell growth factor

Data Image
References

Effect of Metformin on vascular endothelial injury in patients with non-small cell lung cancer treated with chemotherapy combined with bevacizumab., PMID:40522519

[Effect of electroacupuncture on intestinal function after gastric cancer surgery]., PMID:40518778

Home-based online exercise training and chronic, low-grade inflammation in cancer patients after curative surgery: secondary analysis of the randomized controlled multicenter CRBP-TS trial., PMID:40498221

Evaluation of T-cell Function after Blood Transfusion in Patients Undergoing Coronary Artery Bypass Grafting., PMID:40471640

EXPRESS: Key inflammatory mediators drive the resolution of acute Lyme disease., PMID:40459009

T-cell activation enhances anti-HER2-mediated antibody-dependent cellular cytotoxicity in gastric cancer., PMID:40455140

A graded neonatal mouse model of necrotizing enterocolitis demonstrates that mild enterocolitis is sufficient to activate microglia and increase cerebral cytokine expression., PMID:40445990

Expression of an interleukin-2 partial agonist enhances regulatory T cell persistence and efficacy in mouse autoimmune models., PMID:40425532

Effects of Diethylstilbestrol on the Structure and Function of the Spleen in Male Golden Hamsters., PMID:40423476

Streptococcal pyrogenic exotoxin a induces regulatory T cells via TNF-α-TNFR2 signaling., PMID:40402252

Potential common mechanisms between primary Sjögren's syndrome and Hashimoto's thyroiditis: a public databases-based study., PMID:40364944

Pre-existing adipose tissue signaling profile related to obesity determines disease outcome of COVID-19: addressing obesity should be a priority for future pandemic preparedness., PMID:40352457

RNA‑binding protein MBNL1 regulates tumor growth, chemosensitivity and antitumor immunity in lung adenocarcinoma by controlling the expression of tumor suppressor RNF125., PMID:40341413

Causal relationship between circulating inflammatory proteins and atherosclerosis: a bidirectional Mendelian randomization study and meta-analysis., PMID:40339743

White matter hyperintensities, inflammation and cognitive impairments in drug-naïve first episode schizophrenia patients: a cross-sectional study., PMID:40335945

Next-generation probiotics Alistipes onderdonkii enhances the efficacy of anti-PD-1 therapy in colorectal cancer., PMID:40328413

Targeting the intracellular immune checkpoint CISH with CRISPR-Cas9-edited T cells in patients with metastatic colorectal cancer: a first-in-human, single-centre, phase 1 trial., PMID:40315882

BTG2-deficient mast cells remodel the tumor and tumor-draining lymph node microenvironment leading to chemotherapy resistance in breast cancer., PMID:40313959

Low-dose IL-2 restores Tfh/Tfr imbalance and modulates B cell subset distribution in the pre-arthritis phase of the collagen-induced arthritis model., PMID:40304957

Establishment of fracture blister model and analysis of plasma protein markers in rats., PMID:40297588

Inflammatory markers in prostate cancer: potential roles in risk stratification and immune profiling., PMID:40296239

A Germline Heterozygous Dominant Negative IKZF2 Variant Causing Syndromic Primary Immune Regulatory Disorder and ICHAD., PMID:40295428

Association Between Diabetes Mellitus and Allergic Diseases Sensitized by Different Allergens and the Potential Mechanism of Diabetes Mellitus Affecting Ovalbumin-Induced Allergic Rhinitis., PMID:40289517

Distinct temporal profiles of AMPs and cytokines in pleural fluids from open and closed thoracic surgeries and exploration of synergy with antibiotics and wound healing effects., PMID:40268151

Synthetic rEg.P29 Peptides Induce Protective Immune Responses Against Echinococcus granulosus in Mice., PMID:40266142

The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway., PMID:40255567

Moving toward precision and personalized treatment strategies in psychiatry., PMID:40255203

Analysis of preoperative serum cytokine levels in patients with oral squamous cell carcinoma., PMID:40253468

IL-7-mediated expansion of autologous lymphocytes increases CD8+ VLA-4 expression and accumulation in glioblastoma models., PMID:40244705

Enhancing the Anticancer Activity of a Carcinoma-Directed Peptide-HLA-I Fusion Protein by Armoring with Mutein IFNα., PMID:40243928

Exploiting regulatory T cells (Tregs): Cutting-edge therapy for autoimmune diseases., PMID:40215774

Dynamic functional assessment of T cells reveals an early suppression correlating with adverse outcome in polytraumatized patients., PMID:40196124

Implantable Immunostimulant Microneedle Patch for Post-Surgical Prevention of Cancer Recurrence and Distant Tumor Inhibition., PMID:40194999

[Identification of genes regulating human CAR-T cell proliferation by genome-wide CRISPR screening]., PMID:40175136

Cytokine analysis to evaluate severity in primary open-angle glaucoma and exfoliative glaucoma., PMID:40158617

Neuritin-specific antibody impedes the Treg-mediated suppression of anti-tumor immunity and enhances response to anti-PD1., PMID:40153952

Anti-CD137 agonist antibody-independent and clinically feasible preparation of tumor-infiltrating lymphocytes from soft tissue sarcoma and osteosarcoma., PMID:40145091

Effects of Space Flight on Inflammasome Activation in the Brain of Mice., PMID:40136666

Screening helper T lymphocyte epitopes based on IFN-γ/IL-10 ratio for developing a novel multi-epitope vaccine candidate using Wolbachia surface protein as an adjuvant against visceral leishmaniasis., PMID:40134009

Enhanced Antitumor Immunity Through T Cell Activation with Optimized Tandem Double-OX40L mRNAs., PMID:40125432

Exosomes From Adipose-Derived Stem Cells Inhibit Skin T-Cell Activation and Alleviate Wound Inflammation., PMID:40100757

Changes in aqueous humor cytokines and metabolomics in contralateral eye after unilateral cataract surgery., PMID:40098128

Redirecting immune signaling with cytokine adaptors., PMID:40069219

GHSR gene knockout alleviates the liver pathological response in Echinococcus granulosus infection by reducing parasite survival., PMID:40065480

Delineation of monocytic and early-stage myeloid-derived suppressor cells in the peripheral blood of patients with hepatocarcinoma., PMID:40052651

Lung commensal bacteria promote lung cancer progression through NK cell-mediated immunosuppressive microenvironment., PMID:40027183

Neoleukin-2/15-armored CAR-NK cells sustain superior therapeutic efficacy in solid tumors via c-Myc/NRF1 activation., PMID:40025022

Coordinating interleukin-2 encoding circRNA with immunomodulatory lipid nanoparticles to potentiate cancer immunotherapy., PMID:40009662

FAM64A regulates the malignant phenotype and tumor microenvironment of non-small cell lung cancer by activating the JAK/STAT3/PDL1 axis., PMID:39992461

CAR-CIK vs. CAR-T: benchmarking novel cytokine-induced killer cells as solid tumor immunotherapy in ErbB2+ rhabdomyosarcoma., PMID:39963129

Datasheet
$ 300
Product specifications
50 μg 300 100 μg 480

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Recombinant Human IL2 Superkine (Mutant) Protein, C-His (Active) [AHF36804]
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