Catalog No.
AHD46502
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Glu26-His214
Predicted molecular weight
22 kDa
Nature
Recombinant
Endotoxin level
< 0.01 EU/µg as determined by LAL test.
Purity
>90% as determined by SDS-PAGE.
Accession
P21583
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a 0.2 μm filtered solution in 20 mM PB, 150 mM NaCl, pH 7.4.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Stem cell factor, c-Kit ligand, sKITLG, Mast cell growth factor, MGF, Kit ligand, SCF, KITLG
CircRNA_1809 promotes the osteogenic differentiation of bone marrow mesenchymal stem cells through miR-370-3p., PMID:40481048
Predicted plasma proteomics from genetic scores and treatment outcomes in major depression: a meta-analysis., PMID:40408832
OTX2 expression contributes progression of gastric cancer in young adults., PMID:40341176
Prediction of Skin Color Using Forensic DNA Phenotyping in Asian Populations: A Focus on Thailand., PMID:40305359
PTPRG-AS1 regulates the KITLG/KIT pathway through the ceRNA axis to promote the malignant progression of gastric cancer and the intervention effect of Compound Kushen injection on it., PMID:40250508
A Novel Molecular Regulatory Network in Bone Marrow Mesenchymal Stem Cells for Age-Related Osteoporosis., PMID:40145611
Peritoneal Endometriosis Impairs Ovarian Reserve and Increases Atresia in a Rat Model., PMID:40002761
Comparative Analysis Between Olink-PEA and Alamar-NULISA Proteomic Technologies Applied to a Critically Ill COVID-19 Cohort., PMID:39930758
Potential Candidate Genes Associated with Litter Size in Goats: A Review., PMID:39795025
Organophosphate pesticide chlorpyrifos and its metabolite 3,5,6-trichloropyridinol downregulate the expression of genes essential for spermatogenesis in caprine testes., PMID:39277380
A case of familial progressive hyperpigmentation with or without hypopigmentation presenting with hypopigmented striae along the lines of Blaschko., PMID:39269165
Modulation of osteoblastogenesis by NRF2: NRF2 activation suppresses osteogenic differentiation and enhances mineralization in human bone marrow-derived mesenchymal stromal cells., PMID:39230563
Circulating inflammatory proteins and abdominal aortic aneurysm: A two-sample Mendelian randomization and colocalization analyses., PMID:39033731
Comparing machine learning screening approaches using clinical data and cytokine profiles for COVID-19 in resource-limited and resource-abundant settings., PMID:38937503
Transcriptomic Analysis of PDCoV-Infected HIEC-6 Cells and Enrichment Pathways PI3K-Akt and P38 MAPK., PMID:38675921
PGR-KITLG signaling drives a tumor-mast cell regulatory feedback to modulate apoptosis of breast cancer cells., PMID:38556106
Innate Immunity Activation in Newly Diagnosed Ileocolonic Crohn's Disease: A Cohort Study., PMID:38319717
Effects of stem cell factor in follicular fluid and granulosa cells on oocyte maturity and clinical pregnancy., PMID:38206705
Pathway analysis of spermidine anti-oxidative stress and inducing autophagy in granulosa cells of Sichuan white geese., PMID:38118229
Interleukin-30 subverts prostate cancer-endothelium crosstalk by fostering angiogenesis and activating immunoregulatory and oncogenic signaling pathways., PMID:38087324
A novel HMGA2::KITLG fusion in a dedifferentiated liposarcoma with amplification of MDM2 and HMGA2., PMID:37698344
The correlation between primary open-angle glaucoma (POAG) and gut microbiota: a pilot study towards predictive, preventive, and personalized medicine., PMID:37605653
Molecular characterization of the follicular development of BMP15-edited pigs., PMID:37561570
Postnatal Expression of Kitl Affects Pigmentation of the Epidermis., PMID:37482288
Identification of critical genes associated with lead exposure based on in silico analysis., PMID:37178329
Clorfl86/RHEX Is a Negative Regulator of SCF/KIT Signaling in Human Skin Mast Cells., PMID:37174705
The potential role of the KFG and KITLG proteins in preventing granulosa cell apoptosis in Bubalus bubalis., PMID:37000378
The mechanism of Croci stigma in the treatment of melasma based on network pharmacology and molecular docking., PMID:36852722
DAZAP1 facilitates the alternative splicing of KITLG to promote multiple myeloma cell proliferation via ERK signaling pathway., PMID:36242590
KITLG Promotes Glomerular Endothelial Cell Injury in Diabetic Nephropathy by an Autocrine Effect., PMID:36233032
Pathophysiologic Processes and Novel Biomarkers Associated With Congestion in Heart Failure., PMID:36049813
Overexpression of KITLG predicts unfavorable clinical outcomes and promotes lymph node metastasis via the JAK/STAT pathway in nasopharyngeal carcinoma., PMID:35831563
Roan coat color in livestock., PMID:35811453
Leukemia inhibitory factor's effect on the growth and survival of sheep's follicles of ovarian tissue during vitrification., PMID:35780438
Systematic Construction and Validation of a Novel Macrophage Differentiation-Associated Prognostic Model for Clear Cell Renal Cell Carcinoma., PMID:35774505
The SCF/KIT axis in human mast cells: Capicua acts as potent KIT repressor and ERK predominates PI3K., PMID:35652819
Biallelic KITLG variants lead to a distinct spectrum of hypomelanosis and sensorineural hearing loss., PMID:35543077
TGF-β signaling in myeloproliferative neoplasms contributes to myelofibrosis without disrupting the hematopoietic niche., PMID:35439167
Single nucleotide polymorphisms (SNPs) and indels identified from whole-genome re-sequencing of four Chinese donkey breeds., PMID:35382683
Genomic Diversity Profiling and Breed-Specific Evolutionary Signatures of Selection in Arunachali Yak., PMID:35205299
Autocrine/Paracrine Loop Between SCF+/c-Kit+ Mast Cells Promotes Cutaneous Melanoma Progression., PMID:35140718
The association of stem cell factor and soluble c-Kit (s-cKit) receptor serum concentrations with the severity and risk prediction of autism spectrum disorders., PMID:35023029
Adiponectin negatively regulates pigmentation, Wnt/β-catenin and HGF/c-Met signalling within human scalp hair follicles ex vivo., PMID:34854998
Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2., PMID:34851822
Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling., PMID:34818550
Runs of homozygosity analysis reveals population characteristics of yellow-feathered chickens using re-sequencing data., PMID:34747677
De novo mutation in KITLG gene causes a variant of Familial Progressive Hyper- and Hypo-pigmentation (FPHH)., PMID:34716665
Identification of candidate genomic regions for chicken egg number traits based on genome-wide association study., PMID:34376144
Mechanistic models of signaling pathways deconvolute the glioblastoma single-cell functional landscape., PMID:34316686
Familial progressive hyper- and hypopigmentation caused by a novel mutation in site II of the KITLG gene., PMID:34114687
For research use only. Not for human or drug use.
