Catalog No.
AHD00501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala26-Arg221
Predicted molecular weight
24.44 kDa
Nature
Recombinant
Endotoxin level
< 0.01 EU/µg as determined by LAL test.
Purity
>90% as determined by SDS-PAGE.
Accession
P13725
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a 0.2 μm filtered solution in 20 mMTris-HCl, 1 mM EDTA, 200 mM NaCl, pH 7.5.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Oncostatin-M, OSM
Comprehensive Mendelian randomization analysis and experimental investigation identifies the causal relationship between immunity and kidney stone disease., PMID:40498118
Kinesin-2 autoinhibition requires elbow phosphorylation., PMID:40497557
Single-Cell Transcriptomic Profiling Reveals KRAS/TP53-Driven Neutrophil Reprogramming in Luad: A Multi-Gene Prognostic Model and Therapeutic Targeting of RHOV., PMID:40486872
Serum proteins and faecal microbiota as potential biomarkers in newly diagnosed, treatment-naïve inflammatory bowel disease and irritable bowel syndrome patients., PMID:40481885
Multi-omics identifies OSM-OSMR as a key receptor-ligand in the tumor environment of endometrial adenocarcinoma., PMID:40450916
The IL-22-oncostatin M axis promotes intestinal inflammation and tumorigenesis., PMID:40447860
Drug Repurposing to Inhibit Oncostatin M in Crohn's Disease., PMID:40363705
Serum proteomics links the cardiorespiratory biomarkers CTRC, OSM, and MMP-10 to exacerbation severity and number in patients with COPD., PMID:40343765
Oncostatin-M: a novel leukocyte-derived factor facilitating the ovulatory process in the human ovary., PMID:40327872
Proximity extension assay reveals serum inflammatory biomarkers in two amyotrophic lateral sclerosis cohorts., PMID:40306441
Identification and validation of programmed cell death related biomarkers for the treatment and prevention COVID-19., PMID:40300201
Exploring the Role of Inflammation and Metabolites in Bell's Palsy and Potential Treatment Strategies., PMID:40299566
Phosphorylation-dependent regional motility of the ciliary kinesin OSM-3., PMID:40272473
The Radioprotective Effects of 16, 16 dimethyl Prostaglandin E2 on Survival and Hematopoiesis are Mediated Through Co-Stimulation of the EP3 and EP4 Receptors., PMID:40211986
The role of oncostatin M in esophageal cancer and its potential as a prognostic maker., PMID:40198992
Causal Association Between Circulating Inflammatory Proteins and Autoimmune Liver Disease: a Bidirectional Two-Sample Mendelian Randomization Study., PMID:40161480
Oncostatin M silence and neopeptide: the value of exploring patients with rare inherited bone marrow failure., PMID:40091829
Basophil-VAMP7 is a vital regulator of skin barrier integrity and chronic itch., PMID:40089118
Maternal supplementation with α-tocopherol inhibits the development of offspring food allergy, H1R signaling and ultimately anaphylaxis early in life., PMID:40073242
Depletion of eosinophils during sensitization but not challenge phase in mice blocks the development of food allergy early in life., PMID:40073088
DYF-5 regulates intraflagellar transport by affecting train turnaround., PMID:40072497
Transcriptomics-Based Study of Immune Genes Associated with Subclinical Mastitis in Bactrian Camels., PMID:40005880
Proximity extension assay revealed novel inflammatory biomarkers for follicular development and ovarian function: a prospective controlled study combining serum and follicular fluid., PMID:39996063
XDH-1 inactivation causes xanthine stone formation in C. elegans which is inhibited by SULP-4-mediated anion exchange in the excretory cell., PMID:39975063
Canonical prolactin signaling and global mRNA expression in the skin of Holstein heifers carrying the SLICK1 allele of the prolactin receptor gene., PMID:39947597
Bu Yang Huan Wu Prevents Osteogenic Effect of Muscle-Derived Stromal Cells via Regulating JAK/STAT Pathway., PMID:39936922
Characterization of canine tumor-infiltrating leukocyte transcriptomic signatures reveals conserved expression patterns with human osteosarcoma., PMID:39932553
Longitudinal Tear Cytokine Biomarkers: An Analysis from the Close Assessment and Testing for Chronic Graft-Versus-Host Disease (CATCH) Protocol., PMID:39923937
Soluble oncostatin M receptor (sOSMR): A potential biomarker in systemic sclerosis diagnosis., PMID:39894192
Distinct pro-inflammatory/pro-angiogenetic signatures distinguish children with Long COVID from controls., PMID:39849114
Human oncostatin M deficiency underlies an inherited severe bone marrow failure syndrome., PMID:39847438
Efficacy of ramucirumab combined with erlotinib or osimertinib in untreated EGFR-mutated NSCLC patients with asymptomatic brain metastases: insights from molecular biomarkers in the RELAY-brain trial., PMID:39847172
Naringenin, a Food Bioactive Compound, Reduces Oncostatin M Through Blockade of PI3K/Akt/NF-κB Signal Pathway in Neutrophil-like Differentiated HL-60 Cells., PMID:39796391
Keratinocyte-Mediated Antigen Presentation in Psoriasis: Preliminary Insights from In Vitro Studies., PMID:39769151
Anti-TNF nonresponse in ulcerative colitis: correcting for mucosal drug exposure reveals distinct cytokine profiles., PMID:39745888
High cumulative glucocorticoid dose is associated with increased levels of inflammation-related mediators in active rheumatoid arthritis., PMID:39744635
β-Catenin mediated TAM phenotype promotes pancreatic cancer metastasis via the OSM/STAT3/LOXL2 axis., PMID:39740539
P53 and Ki67 Biomarkers are Predictors for Malignant Transformation in Oral Submucous Fibrosis: A Prospective Study., PMID:39733401
Self-assembled nanoparticles of hybrid elastin-like and Oncostatin M polymers for improved wound healing., PMID:39693870
Diversity of Microglia-Derived Molecules with Neurotrophic Properties That Support Neurons in the Central Nervous System and Other Tissues., PMID:39683685
Tryptanthrin Down-Regulates Oncostatin M by Targeting GM-CSF-Mediated PI3K-AKT-NF-κB Axis., PMID:39683503
Tumor-associated macrophages contribute to cholangiocarcinoma progression and chemoresistance through activation of ID1., PMID:39674368
Mediators of Filgotinib Treatment Effects in Ulcerative Colitis: Exploring Circulating Biomarkers in the Phase 2b/3 SELECTION Study., PMID:39656830
Leukemia inhibitory factor (LIF) receptor amplifies pathogenic activation of fibroblasts in lung fibrosis., PMID:39636853
Elastin-like Recombinamers as a Biotechnological Platform for the Development of Cytokine-Functionalized Materials., PMID:39619521
A targeted proteomics screen reveals serum and synovial fluid proteomic signature in patients with gout., PMID:39611154
Molecular Profiling of Mouse Models of Loss or Gain of Function of the KCNT1 (Slack) Potassium Channel and Antisense Oligonucleotide Treatment., PMID:39595574
Effects of Oxidized Soybean Meal and Oxidized Soybean Oil on the Muscle Oxidative Stability, Flesh Quality, Amino Acid Profile, and Fatty Acid Profile of Megalobrama amblycephala., PMID:39594498
Employing urinary biomarkers to infer the absence of acute kidney disease in outpatients with a single serum creatinine measurement., PMID:39593219
Toll-Like receptor 3-mediated interferon-β production is suppressed by oncostatin m and a broader epithelial-mesenchymal transition program., PMID:39593161
For research use only. Not for human or drug use.
