Catalog No.
AHB91603
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Ala279-Ser390
Predicted molecular weight
14.6 kDa
Nature
Recombinant
Endotoxin level
< 0.01 EU/µg as determined by LAL test.
Purity
>90% as determined by SDS-PAGE.
Accession
P01137
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a 0.2 μm filtered solution in 50 mM Glycine-HCl, 150 mM NaCl, pH 2.5.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Transforming growth factor beta-1 proprotein, LAP, TGF-beta-1, TGFB1, TGFB
Panaxatriol saponins exert anti-renal fibrosis by suppressing TNF-α mediated inflammation and TGF-β1/Smad3 signaling pathway., PMID:40534408
Klotho Regulates the Extracellular Matrix Metabolism via TGF-β1/Wnt Signaling Pathway of Fibroblasts in Pelvic Organ Prolapse., PMID:40522286
The Direct and Individual Transcriptional Function of the Human Homodimeric and Heterodimeric Basic Helix-Loop-Helix Transcription Factors E47 and Scleraxis., PMID:40512054
Inhibiting the TGF-β1 Pathway Reduces the Aggressiveness of Intrahepatic CCA HuCCT1 CD90-Positive Cells., PMID:40507785
FOXO1 contributes to cigarette smoke condensate-induced cellular senescence and fibrosis in lung fibroblasts through activating the TGF-β1/Smad2/3 signaling pathway., PMID:40498253
Amygdalin Alleviates Airway Inflammation and Remodeling in Asthma Mice: Involvement of TGF-β1/Smads Signaling Pathway., PMID:40485525
Protective Role of Quercetin in Chronic Atrophic Gastritis: Modulation of Gastric Mucosal Integrity via the Transforming Growth Factor-beta1/Smads Signaling Pathway., PMID:40485522
Plasma proteome profiling of massive perivillous fibrin deposition (MPFD) in women with recurrent Miscarriages: Pathophysiological insights and biomarker discovery., PMID:40472641
Finerenone alleviates the high glucose-induced fibrosis in HK-2 cells by inhibiting EMT via the TGF-β1/Smads signaling., PMID:40436765
Role of Digoxin in Preventing Cigarette Smoke-Induced COPD via HIF-1α Inhibition in a Mouse Model., PMID:40433398
Stromal Interferon Regulatory Factor 3 Can Antagonize Human Papillomavirus Replication by Supporting Epithelial-to-Mesenchymal Transition., PMID:40431610
Mechanism of Curcumol Targeting the OTUB1/TGFBI Ubiquitination Pathway in the Inhibition of Angiogenesis in Colon Cancer., PMID:40430059
Serum expression signature of TUG1, MALAT1, miR-483, and miR-141 and their targets TGF-β1 and STAT3 in severe male factor infertility., PMID:40425698
3,4-Dimethoxycinnamic acid from coffee silverskin biowaste ameliorates bleomycin-induced pulmonary fibrosis via modulating caveolin-1-dependent activation of NF-κB, TGF-β1/Smad3, and ERK1/2 signaling pathways., PMID:40425068
The lncRNA OIP5-AS1/miR-181a-5p Axis Promotes TGF-β1-induced Fibrosis in HK2 Cells., PMID:40424490
Effect of Hyaluronan in Collagen Biomaterials on Human Macrophages and Fibroblasts In Vitro., PMID:40422831
EV-microRNA signatures in pregnant women with idiopathic recurrent pregnancy loss: deciphering microRNAome pathway networks at feto-maternal interface., PMID:40421018
Autophagic degradation of SQSTM1 enables fibroblast activation to accelerate wound healing., PMID:40400126
Functional metabolomics revealed pyroglutamic acid may play a key role in idiopathic pulmonary fibrosis., PMID:40398246
FACS-Proteomics strategy toward extracellular vesicles single-phenotype characterization in biological fluids: exploring the role of leukocyte-derived EVs in multiple sclerosis., PMID:40394633
SKIL Promotes Pancreatic Cancer Metastasis by Inhibiting TSPYL2 to Activate the TGF-β Pathway., PMID:40391200
LncRNA HCG18 regulates the progression of spinal tuberculosis by modulating the hsa-miR-146a-5p/TGF-β1/SMADs pathway., PMID:40390079
ELABELA-32 Alleviates Doxorubicin-Induced Chronic Cardiotoxicity by Inhibiting the TGF-β/Smad Signaling Pathway., PMID:40389799
The effect of T cells on the lncRNA4.9-TGF-β1 axis in HCMV latently infected cells., PMID:40388758
HDAC11 promotes renal fibrosis by induing partial epithelial-mesenchymal transition and G2/M phase arrest in renal epithelial cells., PMID:40386380
Ameliorative effect and potential mechanism of hyperoside on diabetic retinopathy., PMID:40385359
TRIM16 mediates secretory autophagy in head and neck cancer-associated fibroblasts., PMID:40383937
IGFBP7: A novel biomarker involved in a positive feedback loop with TGF-β1 in idiopathic pulmonary fibrosis., PMID:40381971
Maternal high-fat diet exposure impairs LKB1-TGFβ1 inflammatory pathway and increases hypothalamic 5HT receptors gene expression and somatic growth in young rats., PMID:40381902
[Expression of prophybrotic markers TGF-1, MMP-9 and FGFR in the kidneys of patients with urolithiasis during the development of chronic kidney disease]., PMID:40377546
Cannabigerol Alleviates Liver Damage in Metabolic Dysfunction-Associated Steatohepatitis Female Mice via Inhibition of Transforming Growth Factor Beta 1., PMID:40362835
Renometabolic disorder in experimental rat model of polycystic ovarian syndrome is reversed by acetate-mediated inhibition of pyruvate dehydrogenase kinase 4., PMID:40361039
Unraveling the Triad: A Bioinformatics Analysis of the Interplay between Prenatal Depression, Inflammation, and the Gut Microbiota., PMID:40357775
Impact of cardiosphere-derived cells on the maladapted right ventricular muscle in a rat sugen/hypoxia model of pulmonary hypertension with right ventricular dysfunction., PMID:40354360
Smad4 and TGFβ1 dependent gene expression signatures in conditional intestinal adenoma, organoids and colorectal cancer., PMID:40348815
[Shenge powder inhibits myocardial fibrosis in rats with post-myocardial infarction heart failure through LOXL2/TGF-β1/IL-11 signaling pathway]., PMID:40342293
TGF-β1 induces autophagy and mediates the effect on macrophages differentiation in primary liver cancer., PMID:40339499
The up-regulation of TGF-β1 by miRNA-132-3p/WT1 is involved in inducing leukemia cells to differentiate into macrophages., PMID:40327646
Levosimendan mitigates renal fibrosis via TGF-β1/Smad axis modulation in UUO rats., PMID:40319657
Exploration of ACE inhibitory peptides from sea cucumber viscera with DPP-IV inhibitory activity: Virtual screening, characterization, and potential mechanism investigation., PMID:40318712
Neurogranin facilitates maintaining the immunosuppressive state of hepatocellular carcinoma by promoting TGF-β1 secretion., PMID:40316076
TGFB1/CXCL5 axis regulation by LCN2 overexpression: a promising strategy to inhibit colorectal cancer metastasis and enhance prognosis., PMID:40313933
Calcium-Sensing Receptor as a Novel Target for the Treatment of Idiopathic Pulmonary Fibrosis., PMID:40305220
DERL3 facilitates the progression of clear cell renal cell carcinoma by promoting epithelial-mesenchymal transition via regulation of the TGFB1 pathway., PMID:40299934
Immune-related genetic single-nucleotide polymorphisms contribute to prognosis and response to chemotherapy in patients with acute lymphoblastic leukemia., PMID:40299016
Microglia aging in the hippocampus advances through intermediate states that drive activation and cognitive decline., PMID:40298588
Dapagliflozin alleviates thioacetamide induced-liver fibrosis in rats via controlling the Nrf2/HO-1 and TLR4/TGF-β1/PI3K signaling pathways., PMID:40296648
Tricellulin facilitates colorectal cancer metastasis through activation of the TGFβ/SMAD2/3 signalling pathway., PMID:40291908
Mechanism of Green Tea Peptides in Lowering Blood Pressure and Alleviating Renal Injury Induced by Hypertension Through the Ang II/TGF-β1/SMAD Signaling Pathway., PMID:40284165
Proteomic Profiling of Nasal Fluids and Serum for Type 2 Nasal Polyps Diagnosis., PMID:40280274
For research use only. Not for human or drug use.
