Catalog No.
AMA30601
Expression system
Mammalian Cells
Species
Mus musculus (Mouse)
Protein length
Asn25-Ser376
Predicted molecular weight
12.6 kDa & 28.4 kDa
Nature
Recombinant
Endotoxin level
< 1 EU/µg as determined by LAL test.
Purity
>90% as determined by SDS-PAGE.
Accession
O08689
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Liquid
Storage buffer
Supplied as a 0.2 μm filtered solution in PBS, pH 7.4.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Growth/differentiation factor 8, MSTN, GDF-8, Myostatin, GDF8
Direct detection of CRISPR-Cas9 ribonucleoprotein gene doping using RNA immunoprecipitation and quantitative PCR., PMID:40522367
MSTN Regulates Bovine Skeletal Muscle Satellite Cell Differentiation via PSMA6-Mediated AKT Signaling Pathway., PMID:40507774
Multiple ways to promote adult grass carp (Ctenopharyngodon idella) muscle hypertrophy: Application of dietary myo-inositol., PMID:40487104
Rutin-Whey Protein Nanoparticles Inhibit D-Galactose-Induced Skeletal Muscle Dysfunction by Modulating Gut Microbiota and Metabolic Pathways., PMID:40431473
Development and Potent Anti-Tumor Activity of a Fully Humanized Anti-TAG-72-IL-2 Fusion Protein for Therapy of Solid Tumors., PMID:40361381
GDF8 and activin A blockade protects against GLP-1-induced muscle loss while enhancing fat loss in obese male mice and non-human primates., PMID:40360507
GDF8 and activin A are the key negative regulators of muscle mass in postmenopausal females: a randomized phase I trial., PMID:40360471
Improvement in insulin sensitivity following weight loss in obese patients is associated with circulating myostatin., PMID:40350646
Lactylation of muscle proteins is associated with meat quality traits in MSTN-mutated cattle on rigor mortis., PMID:40344421
Skeletal muscle biomarkers of amyotrophic lateral sclerosis: a large-scale, multi-cohort proteomic study., PMID:40313273
Maternal Health and Safety Outcomes of Prenatal Myostatin Inhibition in Osteogenesis Imperfecta Mice., PMID:40305766
Cedrol derivative attenuates muscle atrophy through regulation of myostatin transcription via Ca2+-CaMK-FoxO3a signaling pathways., PMID:40286862
Myostatin Exacerbates Endothelial Dysfunction Induced by Uremic Toxin Indoxyl Sulfate and Is Associated with Hemodialysis Arteriovenous Access Complications., PMID:40278657
Relationship between myostatin, musclin, nutritional status, and functionality in older Colombian community-dwelling adults: A cross-sectional study., PMID:40267554
Inhibiting Myostatin Expression by the Antisense Oligonucleotides Improves Muscle Wasting in a Chronic Kidney Disease Mouse Model., PMID:40243849
Comparative analysis of reproductive organs, hormones and blood metabolism of MSTN mutated and non-mutated cows during gestation., PMID:40241099
Effect of one copy of the nt821 mutation in the myostatin gene on yearling traits in Senepol cattle., PMID:40214706
CRISPR/Cas9-mediated myostatin disruption elevates the expression of genes associated with myofiber composition and growth in Exopalaemon carinicauda., PMID:40207549
Myokines as potential mediators of changes in glucose homeostasis and muscle mass after bariatric surgery., PMID:40171198
Presence of a Deletion Mutation of Myostatin (MSTN) Gene Associated With Double-Muscling Phenotype in Japanese Black Cattle Population., PMID:40170586
Testosterone/androgen receptor antagonizes immobility-induced muscle atrophy through Inhibition of myostatin transcription and inflammation in mice., PMID:40148525
Relationship between the expression levels of myogenic regulatory factor genes and carcass characteristics in Kivircik and Hungarian Merino lambs., PMID:40122069
Dysfunctional terminal differentiation of satellite cells in the wooden breast muscle of Ross 308 broiler chickens., PMID:40121757
A functional role for myostatin in muscle hyperplasia and hypertrophy revealed by comparative transcriptomics in Yesso scallop Patinopecten yessoensis., PMID:40118415
The Effect of Selection on the Two Important Myostatin Gene Mutations in the Dareshouri Horse in the Middle East., PMID:40104884
Effects of breed, diet and sex on expression of growth-related genes in Nigerian goats., PMID:40088337
Growth patterns and heat tolerance analysis of dwarf chicken with frizzled feather., PMID:40073636
MSTN knockout enhances the production of MYOD1-mediated steak-type cultivated meat., PMID:40065420
Genetic subtyping of obesity reveals biological insights into the uncoupling of adiposity from its cardiometabolic comorbidities., PMID:40061343
Myostatin Knockout Mice Have Larger Muscle Fibers With Normal Function and Morphology., PMID:40026240
Comprehensive analysis of circRNAs and lncRNAs involvement in the development of skeletal muscle in myostatin-deficient rabbits., PMID:40009466
Interaction of dietary replacements of fishmeal by protein blend and feeding frequency on growth performance and protein utilization of gibel carp (Carassius gibelio var. CAS V)., PMID:39995523
CRISPR/Cas9-Targeted Myostatin Deletion Improves the Myogenic Differentiation Parameters for Muscle-Derived Stem Cells in Mice., PMID:39982358
Comprehensive transcriptomic analysis of myostatin-knockout pigs: insights into muscle growth and lipid metabolism., PMID:39979478
Changes in Protein Metabolism and Early Development of Sarcopenia in Mice With Cholestatic Liver Disease., PMID:39971588
MSTN gene knockout suppresses the activation of lung fibroblasts through the inhibition of the Smad/AKT signaling pathway, thereby ameliorating pulmonary fibrosis., PMID:39971222
The polyphenol metabolite urolithin A suppresses myostatin expression and augments glucose uptake in human skeletal muscle cells., PMID:39962542
Endurance exercise remodels skeletal muscle by suppressing Ythdf1-mediated myostatin expression., PMID:39948064
Long-Day Photoperiod Improves the Growth and Muscle Quality of Grass Carp (Ctenopharyngodon idella)., PMID:39942096
A review of myostatin gene mutations: Enhancing meat production and potential in livestock genetic selection., PMID:39927343
Optimized electroporation buffer improves transfection and prime editing efficiency in adult bovine fibroblasts., PMID:39922551
Effect of blocking transforming growth factor-β/Activin-Myostatin signaling on the expression of ecdysteroid metabolism and responsive genes in the crustacean molting gland (Y-organ)., PMID:39922321
PrPC Glycoprotein Is Indispensable for Maintenance of Skeletal Muscle Homeostasis During Aging., PMID:39873124
Myokines: metabolic regulation in obesity and type 2 diabetes., PMID:39872377
The Bile Acid Metabolism of Intestinal Microorganisms Mediates the Effect of Different Protein Sources on Muscle Protein Deposition in Procambarus clarkii., PMID:39858779
Muscle-derived myostatin is a major endocrine driver of follicle-stimulating hormone synthesis., PMID:39818879
The Effects of Laxogenin and 5-Alpha-hydroxy-laxogenin on Myotube Formation and Maturation During Cultured Meat Production., PMID:39796200
The Impact of MSTN Gene Editing on Meat Quality and Metabolomics: A Comparative Study Among Three Breeds of MSTN-Edited and Non-Edited Cattle., PMID:39794990
Genotypic Influences on Actuators of Aerobic Performance in Tactical Athletes., PMID:39766802
Loss of Myostatin leads to low production of CH4 by altering rumen microbiota and metabolome in cattle., PMID:39761884
For research use only. Not for human or drug use.
