Catalog No.
YHC99601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Phe505-Thr636
Predicted molecular weight
17.09 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P13667
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ERp-72, ER protein 70, ER protein 72, ERP70, Protein disulfide-isomerase A4, ERP72, PDIA4, Endoplasmic reticulum resident protein 72, ERp72, ERp70, Endoplasmic reticulum resident protein 70
Small extracellular vesicles from HO-1 modified BMMSCs alleviate steatotic liver grafts ischemia-reperfusion injury by delivering PDIA4 to promote reparative macrophage polarization., PMID:40494182
Serpina3c Mitigates Adipose Tissue Inflammation by Inhibiting the HIF1α-Mediated Endoplasmic Reticulum Overoxidation in Adipocytes., PMID:40403760
Protein disulphide isomerase A4 as a potential biomarker for coronavirus disease 2019: Correlation with cytokine profiles and disease progression., PMID:40391685
Deciphering the Molecular Crosstalk of Endoplasmic Reticulum Stress and Immune Infiltration in Endometriosis., PMID:40371728
QKI-induced circ_0001766 inhibits colorectal cancer progression and rapamycin resistance by miR-1203/PPP1R3C/mTOR/Myc axis., PMID:40263288
PSP205, a Novel Phenyl Sulfonyl Piperidine, Induces Apoptotic Cell Death in Colon Cancer by Modulating Coat Protein Complex-Mediated Vesicle Trafficking., PMID:40242573
Unraveling shared diagnostic genes and cellular microenvironmental changes in endometriosis and recurrent implantation failure through multi-omics analysis., PMID:40097519
Multiomic analyses direct hypotheses for Creutzfeldt-Jakob disease risk genes., PMID:39865733
Spatial covariance reveals isothiocyanate natural products adjust redox stress to restore function in alpha-1-antitrypsin deficiency., PMID:39809267
PDIA4 targets IRE1α/sXBP1 to alleviate NLRP3 inflammasome activation and renal tubular injury in diabetic kidney disease., PMID:39743023
Characterization of the Ubiquitin-Modified Proteome of Recombinant Chinese Hamster Ovary Cells in Response to Endoplasmic Reticulum Stress., PMID:39623727
DLL4-targeted CAR-T therapy sensitizes neoadjuvant chemotherapy via eliminating cancer stem cells and reshaping immune microenvironment in HER2+ breast cancer., PMID:39542653
A transcriptomics-based analysis of mechanisms involved in the neurobehavioral effects of 6PPD-quinone on early life stages of zebrafish., PMID:39454255
Effects of treadmill exercise on endoplasmic reticulum protein folding and endoplasmic reticulum-associated protein degradation pathways in APP/PS1 mice., PMID:39397952
Potential Anti-tumor Properties of PDIA4 in Lung Adenocarcinoma., PMID:39348977
Protein disulfide isomerase A4 binds to Brucella BtpB and mediates intracellular NAD+/NADH metabolism in RAW264.7 cells., PMID:39226825
Genetic insights into drug targets for sporadic Creutzfeldt-Jakob disease: Integrative multi-omics analysis., PMID:38996988
Amplifying colorectal cancer progression: impact of a PDIA4/SP1 positive feedback loop by circPDIA4 sponging miR-9-5p., PMID:38907517
Quantitative proteomics reveals cellular responses to individual mAb expression and tunicamycin in CHO cells., PMID:38896138
Protein Disulfide Isomerase 4 Is an Essential Regulator of Endothelial Function and Survival., PMID:38612722
Serum biomarkers in patients with drug-resistant epilepsy: a proteomics-based analysis., PMID:38585359
Hepatitis E virus ORF3 protein hijacking thioredoxin domain-containing protein 5 (TXNDC5) for its stability to promote viral particle release., PMID:38548704
Screening the critical protein subnetwork to delineate potential mechanisms and protective agents associated with arsenic-induced cutaneous squamous cell carcinoma: A toxicogenomic study., PMID:38219847
Protein disulfide isomerase family member 4 promotes triple-negative breast cancer tumorigenesis and radiotherapy resistance through JNK pathway., PMID:38167446
Development of a prognostic model for glioblastoma multiforme based on the expression levels of efferocytosis-related genes., PMID:38159261
PDIA4 Is a Host Factor Important for Lymphocytic Choriomeningitis Virus Infection., PMID:38140584
Proteomics analysis of serum and urine identifies VCP and CTSA as potential biomarkers associated with multiple myeloma., PMID:38081446
Proteomic Analysis of Frozen-Thawed Spermatozoa with Different Levels of Freezability in Dairy Goats., PMID:37958534
Exploring the Common Gene Signatures Between Myocardial Infarction-Reperfusion Injury and the Gut Microbiome Using Bioinformatics., PMID:37920088
LncRNA FAM225B Regulates PDIA4-Mediated Ovarian Cancer Cell Invasion and Migration via Modulating Transcription Factor DDX17., PMID:37720188
ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones., PMID:37705743
Small extracellular vesicles-transported lncRNA TDRKH-AS1 derived from AOPPs-treated trophoblasts initiates endothelial cells pyroptosis through PDIA4/DDIT4 axis in preeclampsia., PMID:37488572
A Novel HOXA10-Associated 5-Gene-Based Prognostic Signature for Stratification of Short-term Survivors of Pancreatic Ductal Adenocarcinoma., PMID:37432996
MST1R as a potential new target antigen of chimeric antigen receptor T cells to treat solid tumors., PMID:37078298
Protein disulfide-isomerase A4 confers glioblastoma angiogenesis promotion capacity and resistance to anti-angiogenic therapy., PMID:36997943
Pharmacological and mechanistic study of PS1, a Pdia4 inhibitor, in β-cell pathogenesis and diabetes in db/db mice., PMID:36935456
[Crosstalk between activating transcription factor 6 and the inositol-requiring enzyme 1-X-box binding protein 1 pathway in oxygen-glucose deprivation/reoxygenation-injured HT22 cells]., PMID:36916341
PDIA4 confers resistance to ferroptosis via induction of ATF4/SLC7A11 in renal cell carcinoma., PMID:36906674
SARS-CoV-2 ORF8 Protein Induces Endoplasmic Reticulum Stress-like Responses and Facilitates Virus Replication by Triggering Calnexin: an Unbiased Study., PMID:36877072
Construction and validation of a cuproptosis-related prognostic model for glioblastoma., PMID:36814929
PDIA4, a new endoplasmic reticulum stress protein, modulates insulin resistance and inflammation in skeletal muscle., PMID:36619574
CircPDIA4 Induces Gastric Cancer Progression by Promoting ERK1/2 Activation and Enhancing Biogenesis of Oncogenic circRNAs., PMID:36562654
MicroRNA miR-378-3p is a novel regulator of endothelial autophagy and function., PMID:39803361
Identification of molecular subtypes based on chromatin regulator and tumor microenvironment infiltration characterization in papillary renal cell carcinoma., PMID:36404389
Association of protein disulfide isomerase family A, member 4, and inflammation in people living with HIV., PMID:36375691
Albumin (ALB) and protein disulfide isomerase family A member 4 (PDIA4) are novel markers to predict sperm freezability of Erhualian boar., PMID:36181861
High expression of PDIA4 promotes malignant cell behavior and predicts reduced survival in cervical cancer., PMID:36082822
Comparative Proteomic Profiling of Cisplatin-resistant Nasopharyngeal Carcinoma Cell Lines: Novel Biomarkers for Improving Chemotherapy of NPC., PMID:35790268
Using Next-Generation Sequencing and Bioinformatic Methods to Predict New Genes That May Be Regulated by CD47 in Oral Squamous Cell Carcinoma., PMID:35678681
PDIA4, a novel ER stress chaperone, modulates adiponectin expression and inflammation in adipose tissue., PMID:35674710
For research use only. Not for human or drug use.
