Catalog No.
RHK63201
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:1000-1:2000
Target
HsMAD1, MAD1-like protein 1, hMAD1, Mitotic arrest deficient 1-like protein 1, Tax-binding protein 181, MAD1, TXBP181, Mitotic checkpoint MAD1 protein homolog, MAD1L1, Mitotic spindle assembly checkpoint protein MAD1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9Y6D9
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2M64
Association Between Peptide Antigen-Related Antibody Levels and the Short- and Long-Term Efficacy of Antipsychotic Treatment in Drug-Naïve First-Episode Schizophrenia Patients., PMID:39673496
The closed form of Mad2 is bound to Mad1 and Cdc20 at unattached kinetochores., PMID:29895228
Study of Novel Autoantibodies in Schizophrenia., PMID:29373732
Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint., PMID:26031201
Structure of human Mad1 C-terminal domain reveals its involvement in kinetochore targeting., PMID:22493223
Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpoint., PMID:21772247
PRP4 is a spindle assembly checkpoint protein required for MPS1, MAD1, and MAD2 localization to the kinetochores., PMID:17998396
Localization of mitotic arrest deficient 1 (MAD1) in mouse oocytes during the first meiosis and its functions as a spindle checkpoint protein., PMID:15342357
Dynamics of centromere and kinetochore proteins; implications for checkpoint signaling and silencing., PMID:15182667
Inhibition of the epidermal growth factor receptor suppresses telomerase activity in HSC-1 human cutaneous squamous cell carcinoma cells., PMID:14708611
Spindle checkpoint proteins Mad1 and Mad2 are required for cytostatic factor-mediated metaphase arrest., PMID:14691134
Nuf2 and Hec1 are required for retention of the checkpoint proteins Mad1 and Mad2 to kinetochores., PMID:14654001
Anaphase onset does not require the microtubule-dependent depletion of kinetochore and centromere-binding proteins., PMID:12235289
Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint., PMID:11707408
Expression of Mad1 in T cells leads to reduced thymic cellularity and impaired mitogen-induced proliferation., PMID:11313860
Contrasting localization of c-Myc with other Myc superfamily transcription factors in the human hair follicle and during the hair growth cycle., PMID:11286633
Mitotic checkpoint proteins HsMAD1 and HsMAD2 are associated with nuclear pore complexes in interphase., PMID:11181178
Co-induction of Mad1 and c-Myc in activated normal B lymphocytes., PMID:10849366
Analysis of the DNA-binding activities of Myc/Max/Mad network complexes during induced differentiation of U-937 monoblasts and F9 teratocarcinoma cells., PMID:9264414
Inhibition of c-myc expression induces apoptosis of WEHI 231 murine B cells., PMID:8756660
Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast., PMID:7593191
For research use only. Not for human or drug use.
