Catalog No.
YHC97001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Lys250
Predicted molecular weight
30.27 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P13284
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IP30, GILT, Gamma-interferon-inducible protein IP-30, IFI30, Legumaturain, Gamma-interferon-inducible lysosomal thiol reductase
IFI30 Knockdown Inhibits ESCC Progression by Promoting Apoptosis and Senescence via Activation of JNK and P21/P16 Pathways., PMID:40186402
Inhibition of STAT1 alleviates oxidative damage in retinal pigment epithelial cells and exhibits neuroprotective effects in autoimmune optic neuritis by upregulating IFI30 lysosomal thiol reductase., PMID:40152123
Integrative gut microbiota, metabolomics and proteomics studies unraveled the mechanism of Shaoteng decoction in treating Sjogren's syndrome., PMID:40088738
The Prognostic Role of Interferon Gamma-inducible Protein 30 in Clear Cell Renal Cell Carcinoma with Immune Infiltrates., PMID:39936439
Single-cell transcriptomics analysis reveals dynamic changes and prognostic signature in tumor microenvironment of PDAC., PMID:39894886
Multi-omics joint screening of biomarkers related to M2 macrophages in gastric cancer., PMID:39623254
RNA editing in response to COVID-19 vaccines: unveiling dynamic epigenetic regulation of host immunity., PMID:39308856
Post-Transcriptional Induction of the Antiviral Host Factor GILT/IFI30 by Interferon Gamma., PMID:39273610
Interferon Gamma Inducible Protein 30: from biological functions to potential therapeutic target in cancers., PMID:39141317
Nudt15-mediated inflammatory signaling contributes to divergent outcomes in leukemogenesis and hematopoiesis., PMID:39025986
Identification of the molecular subtypes and signatures to predict the prognosis, biological functions, and therapeutic response based on the anoikis-related genes in colorectal cancer., PMID:38785271
IFI30 as a key regulator of PDL1 immunotherapy prognosis in breast cancer., PMID:38669947
Identification and validation of a novel signature based on macrophage marker genes for predicting prognosis and drug response in kidney renal clear cell carcinoma by integrated analysis of single cell and bulk RNA sequencing., PMID:38517387
Identification and validation of CRLF1 and NRG1 as immune-related signatures in hypertrophic scar., PMID:38262564
[Knockdown of interferon-γ inducible protein 30 (IFI30) inhibits the proliferation, invasion and migration of human glioma U251 cells by activating STAT1 and promotes their apoptosis]., PMID:38246175
A Transcription Factor ZNF384, Regulated by LINC00265, Activates the Expression of IFI30 to Stimulate Malignant Progression in Glioma., PMID:38141017
Comprehensive analysis of the role of interferon gamma-inducible protein 30 on immune infiltration and prognosis in clear cell renal cell carcinoma., PMID:37991414
Cerebrospinal Fluid Proteomic Changes after Nusinersen in Patients with Spinal Muscular Atrophy., PMID:37892834
Dissection of paracrine/autocrine interplay in lung tumor microenvironment mimicking cancer cell-monocyte co-culture models reveals proteins that promote inflammation and metastasis., PMID:37784035
Identification of monocyte-associated biomarkers in systemic lupus erythematosus and their pan-cancer analysis., PMID:37769649
Subcutaneous adipose tissue alteration in aging process associated with thyroid hormone signaling., PMID:37626392
Interferon-γ inducible protein 30 promotes the epithelial-mesenchymal transition-like phenotype and chemoresistance by activating EGFR/AKT/GSK3β/β-catenin pathway in glioma., PMID:37408388
Nanoplastics enhance the intestinal damage and genotoxicity of sulfamethoxazole to medaka juveniles (Oryzias melastigma) in coastal environment., PMID:37329919
Identification of immune cell infiltration and diagnostic biomarkers in unstable atherosclerotic plaques by integrated bioinformatics analysis and machine learning., PMID:36211422
Differentially expressed liver exosome-related genes as candidate prognostic biomarkers for hepatocellular carcinoma., PMID:36034976
Ifi30 Is Required for Sprouting Angiogenesis During Caudal Vein Plexus Formation in Zebrafish., PMID:35910561
IDO1, FAT10, IFI6, and GILT Are Involved in the Antiretroviral Activity of γ-Interferon and IDO1 Restricts Retrovirus Infection by Autophagy Enhancement., PMID:35883685
Propofol Suppresses Glioma Tumorigenesis by Regulating circ_0047688/miR-516b-5p/IFI30 Axis., PMID:35763173
A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation., PMID:35654975
Construction of three-gene-based prognostic signature and analysis of immune cells infiltration in children and young adults with B-acute lymphoblastic leukemia., PMID:35603962
Identification of novel prognostic targets in glioblastoma using bioinformatics analysis., PMID:35436915
Stress and the brain transcriptome: Identifying commonalities and clusters in standardized data from published experiments., PMID:35405299
Urinary Sediment mRNA Level of CREBBP and CYBA in Children With Steroid-Resistant Nephrotic Syndrome., PMID:35173708
IFI30 as a prognostic biomarker and correlation with immune infiltrates in glioma., PMID:34988195
Autoimmune regulator act in synergism with thymocyte adhesion in the control of lncRNAs in medullary thymic epithelial cells., PMID:34700158
Prognostic value of gamma-interferon-inducible lysosomal thiol reductase expression in female patients diagnosed with breast cancer., PMID:34648659
Distinct Hepatic Gene-Expression Patterns of NAFLD in Patients With Obesity., PMID:34558849
IFI30 expression predicts patient prognosis in breast cancer and dictates breast cancer cells proliferation via regulating autophagy., PMID:34400904
A connexin/ifi30 pathway bridges HSCs with their niche to dampen oxidative stress., PMID:34301940
Expression of gilt acts as a positive regulator of mouse hematopoietic progenitor cells., PMID:34015674
GILT in tumor cells improves T cell-mediated anti-tumor immune surveillance., PMID:33838181
Systematically Characterizing A-to-I RNA Editing Neoantigens in Cancer., PMID:33363023
Single-Cell Transcriptome Analysis Highlights a Role for Neutrophils and Inflammatory Macrophages in the Pathogenesis of Severe COVID-19., PMID:33138195
IFI30 expression is an independent unfavourable prognostic factor in glioma., PMID:32969157
The association of genetic variants IL2RA rs2104286, IFI30 rs11554159 and IKZF3 rs12946510 with multiple sclerosis onset and severity in patients from Serbia., PMID:32738499
The circRNA circIFI30 promotes progression of triple-negative breast cancer and correlates with prognosis., PMID:32497020
GILT in Thymic Epithelial Cells Facilitates Central CD4 T Cell Tolerance to a Tissue-Restricted, Melanoma-Associated Self-Antigen., PMID:32269095
NGS Evaluation of Colorectal Cancer Reveals Interferon Gamma Dependent Expression of Immune Checkpoint Genes and Identification of Novel IFNγ Induced Genes., PMID:32265897
Targeted resequencing reveals rare variants enrichment in multiple sclerosis susceptibility genes., PMID:32196808
GILT restricts the cellular entry mediated by the envelope glycoproteins of SARS-CoV, Ebola virus and Lassa fever virus., PMID:31631785
For research use only. Not for human or drug use.
