Catalog No.
RHJ75401
Species reactivity
Human, Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:1000-1:2000
Target
EBF, EBF1, OE-1, COE1, Early B-cell factor, Transcription factor COE1, O/E-1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UH73
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2K74
Differentiation-dependent EBF1 Activity Determines CD22 Transcription and Leukemia Sensitivity to Inotuzumab Ozogamicin., PMID:40435412
Transcriptional function of E2A, Ebf1, Pax5, Ikaros and Aiolos analyzed by in vivo acute protein degradation in early B cell development., PMID:39179932
Three-dimensional chromatin reorganization regulates B cell development during ageing., PMID:38866970
A human-specific insertion promotes cell proliferation and migration by enhancing TBC1D8B expression., PMID:38110796
EBF1, MYO6 and CALR expression levels predict therapeutic response in diffuse large B-cell lymphomas., PMID:38035116
Tnpo3 enables EBF1 function in conditions of antagonistic Notch signaling., PMID:36167471
Deficiency of p53 Causes the Inadequate Expression of miR-1246 in B Cells of Systemic Lupus Erythematosus., PMID:36165173
Measurable residual disease analysis in paediatric acute lymphoblastic leukaemia patients with ABL-class fusions., PMID:35650277
IL-7R signaling activates widespread VH and DH gene usage to drive antibody diversity in bone marrow B cells., PMID:34260907
Philadelphia chromosome-negative B-cell acute lymphoblastic leukaemia with kinase fusions in Taiwan., PMID:33707599
Abnormal thymic B cell activation and impaired T cell differentiation in pristane-induced lupus mice., PMID:33428991
Negative Regulation of TLR Signaling by BCAP Requires Dimerization of Its DBB Domain., PMID:32198144
Immunogenetics of marsupial B-cells., PMID:31726269
Potential Markers of Autoimmune Diseases, Alleles rs115662534(T) and rs548231435(C), Disrupt the Binding of Transcription Factors STAT1 and EBF1 to the Regulatory Elements of Human CD40 Gene., PMID:30878028
Epstein-Barr virus-encoded EBNA2 alters immune checkpoint PD-L1 expression by downregulating miR-34a in B-cell lymphomas., PMID:29946193
Dynamic EBF1 occupancy directs sequential epigenetic and transcriptional events in B-cell programming., PMID:29440261
Application of gene specific mRNA level determinations in individual cells using flow cytometry-based PrimeFlow™ in immunotoxicology., PMID:29107001
Antagonism of B cell enhancer networks by STAT5 drives leukemia and poor patient survival., PMID:28369050
Applied Protein and Molecular Techniques for Characterization of B Cell Neoplasms in Horses., PMID:26311245
The chromatin remodeler Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth., PMID:25985234
Ebf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiency., PMID:25838350
Hind limb unloading, a model of spaceflight conditions, leads to decreased B lymphopoiesis similar to aging., PMID:25376832
The survival and differentiation of pro-B and pre-B cells in the bone marrow is dependent on IL-7Rα Tyr449., PMID:25143441
B cell signatures of BCWD-resistant and susceptible lines of rainbow trout: a shift towards more EBF-expressing progenitors and fewer mature B cells in resistant animals., PMID:25101978
Ikaros is absolutely required for pre-B cell differentiation by attenuating IL-7 signals., PMID:24297995
Early B-cell factor 1 regulates the expansion of B-cell progenitors in a dose-dependent manner., PMID:24078629
A capture-sequencing strategy identifies IRF8, EBF1, and APRIL as novel IGH fusion partners in B-cell lymphoma., PMID:23775715
Cellular origin and pathophysiology of chronic lymphocytic leukemia., PMID:23091163
MBD2 and multiple domains of CHD4 are required for transcriptional repression by Mi-2/NuRD complexes., PMID:23071088
IGH@ translocations, CRLF2 deregulation, and microdeletions in adolescents and adults with acute lymphoblastic leukemia., PMID:22851563
Genome-wide detection of genes targeted by non-Ig somatic hypermutation in lymphoma., PMID:22808135
Essential role of EBF1 in the generation and function of distinct mature B cell types., PMID:22473956
Expression of essential B cell development genes in horses with common variable immunodeficiency., PMID:22464097
Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells., PMID:22431510
The complexity of Sjögren's syndrome: novel aspects on pathogenesis., PMID:21777618
The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow., PMID:21423172
Identification of direct downstream targets of Dlx5 during early inner ear development., PMID:21227998
Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome., PMID:20861858
Chromosome dynamics and the regulation of V(D)J recombination., PMID:20727028
Comparative analyses of B cell populations in trout kidney and mouse bone marrow: establishing "B cell signatures"., PMID:20705088
Emerging roles of the EBF family of transcription factors in tumor suppression., PMID:19996307
Early B cell factor: Regulator of B lineage specification and commitment., PMID:18722139
Two levels of protection for the B cell genome during somatic hypermutation., PMID:18273020
Expression of SNC73, a transcript of the immunoglobulin alpha-1 gene, in human epithelial carcinomas., PMID:17511028
Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits., PMID:17363301
HDAC2 controls IgM H- and L-chain gene expressions via EBF1, Pax5, Ikaros, Aiolos and E2A gene expressions., PMID:17352740
The HSS3/4 enhancer of Crlz1-IgJ locus is another target of EBF in the pre-B cell stage of B cell development., PMID:16962668
Evi3, a zinc-finger protein related to EBFAZ, regulates EBF activity in B-cell leukemia., PMID:15580294
Neuroblastoma and pre-B lymphoma cells share expression of key transcription factors but display tissue restricted target gene expression., PMID:15544702
Assembly and analysis of the mouse immunoglobulin kappa gene sequence., PMID:15378297
For research use only. Not for human or drug use.
