Catalog No.
YHC92301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Phe671-Cys1019
Predicted molecular weight
41.47 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P12110
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
COL6A2, Collagen alpha-2(VI) chain
A diet-driven metabolic dysfunction-associated steatohepatitis (MASH) mouse model resembles the corresponding human disease., PMID:40392411
Blood biochemical landscape and new insights into clinical decision-making for polycystic ovary syndrome in Chinese women: a prospective cohort study., PMID:40375948
Elucidating the Predominant Role of AEBP1 in Different Types of Cancers with a Focus on Glioblastoma Progression - A Review., PMID:40375702
Collagen type VI regulates TGF-β bioavailability in skeletal muscle in mice., PMID:40309777
Altered expression of collagen gene family members and its epigenetic background in equine Sarcoids., PMID:40288239
Clinical, Pathologic, and Genetic Spectrum of Collagen VI-Related Disorder in China-A Retrospective Observational Multicenter Study., PMID:40225934
Regulatory role of miR-128-2-5p in serum exosomes on COL6A2 expression and postmenopausal osteoporosis., PMID:39817546
Suppressing the progression of bladder cancer using cyclovirobuxine D based on network pharmacology and bioinformatics approaches., PMID:39797986
A diagnostic signatures for intervertebral disc degeneration using TNFAIP6 and COL6A2 based on single-cell RNA-seq and bulk RNA-seq analyses., PMID:39704340
Segregation of the COL6A2 Variant (c.1817-3C>G) in a Consanguineous Saudi Family with Bethlem Myopathy., PMID:39596604
Restored Collagen VI Microfilaments Network in the Extracellular Matrix of CRISPR-Edited Ullrich Congenital Muscular Dystrophy Fibroblasts., PMID:39595588
A Novel Splice Site Variant in COL6A1 Causes Ullrich Congenital Muscular Dystrophy in a Consanguineous Malian Family., PMID:39523858
Label-based comparative proteomics of oral mucosal tissue to understand progression of precancerous lesions to oral squamous cell carcinoma., PMID:39483176
Proteomic Characterization of Corneal Epithelial and Stromal Cell-Derived Extracellular Vesicles., PMID:39408670
Mutations in COL6A Gene Family Responsible for Muscular Dystrophies in Three Unrelated Families., PMID:39397694
Changes of collagen content in lung tissues of plateau yak and its mechanism of adaptation to hypoxia., PMID:39372716
Distinct muscle regenerative capacity of human induced pluripotent stem cell-derived mesenchymal stromal cells in Ullrich congenital muscular dystrophy model mice., PMID:39370505
Clinical and Molecular Profiles of a Cohort of Egyptian Patients with Collagen VI-Related Dystrophy., PMID:39367186
Expert panel curation of 31 genes in relation to limb girdle muscular dystrophy., PMID:39215466
Synovial expression of glucocorticoid receptor parallels fibroblast activation in patients with rheumatoid arthritis., PMID:39105347
Extracellular Matrix Protein Signatures of the Outer and Inner Zones of the Rat Adrenal Cortex., PMID:39018382
A novel cancer-associated fibroblasts risk score model predict survival and immunotherapy in lung adenocarcinoma., PMID:39017768
The lung extracellular matrix protein landscape in severe early-onset and moderate chronic obstructive pulmonary disease., PMID:38915286
Identification of key modules and hub genes involved in regulating the feather follicle development of Wannan chickens using WGCNA., PMID:38908121
A novel interplay between PRC2 and miR-3189 regulates epithelial-mesenchymal transition (EMT) via modulating COL6A2 in glioblastoma., PMID:38860406
Expression Profiles and Bioinformatic Analysis of Circular RNAs in Db/Db Mice with Cardiac Fibrosis., PMID:38799279
Proteomic profile of tissue-derived extracellular vesicles from benign odontogenic lesions., PMID:38795909
AP-1-dependent fibrosis: Exploring its potential role in the pathogenesis of placental transmogrification of the lung (PTL) via tissue-level transcriptome analysis., PMID:38718468
Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer's disease., PMID:38598053
Exploring the evolutionary mechanism of hepatitis B and gastric cancer based on Mendelian randomization combined with bioinformatics analysis., PMID:38579038
RNA Sequencing Reveals the Inhibitory Effect of High Levels of Arachidonic Acid and Linoleic Acid on C2C12 Differentiation and Myogenic Biomarkers., PMID:38474834
Urinary exosomal mRNA as a biomarker for the diagnosis of bladder cancer., PMID:38385960
System biology approaches to identify hub genes linked with ECM organization and inflammatory signaling pathways in schizophrenia pathogenesis., PMID:38322840
Transcriptomic and proteomic strategies to reveal the mechanism of Gymnocypris przewalskii scale development., PMID:38310220
Rare genetic variation in Fibronectin 1 ( FN1 ) protects against APOEe4 in Alzheimer's disease., PMID:38260431
Transcriptome research of human amniocytes identifies hub genes associated with developmental dysplasia in down syndrome., PMID:38095646
Spontaneous mutation in the COL6A2 gene causing Ullrich congenital muscular dystrophy type 1 in a Chinese child: A case report., PMID:38065855
Collagen gene cluster expression and liver fibrogenesis in patients with biliary atresia: a preliminary study., PMID:38041174
Immunobiology of foreign body response to composite PLACL/gelatin electrospun nanofiber meshes with mesenchymal stem/stromal cells in a mouse model: Implications in pelvic floor tissue engineering and regeneration., PMID:37980818
4D DIA-PRM proteomic study identifying modulated pathways and biomarkers associated with pelvic organ prolapse., PMID:37922782
Explore novel molecular mechanisms of FNDC5 in ischemia-reperfusion (I/R) injury by analyzing transcriptome changes in mouse model of skeletal muscle I/R injury with FNDC5 knockout., PMID:37918465
COL3A1, COL5A1 and COL6A2 serve as potential molecular biomarkers for osteoarthritis based on weighted gene co‑expression network analysis bioinformatics analysis., PMID:37869636
Identification and validation of key genes associated with pathogenesis and prognosis of gastric cancer., PMID:37868053
Identifying Crucial Biomarkers in Osteoporosis and Ulcerative Colitis Through Bioinformatics Analysis of Co-expressed Genes., PMID:37842511
Unexpected partial RNA deletion by two different novel COL6A2 mutations leads to Ullrich congenital muscular dystrophy., PMID:37738610
Exploration of diagnostic biomarkers, microenvironment characteristics, and ursolic acid's therapeutic effect for benign prostate hyperplasia., PMID:37705744
Single-cell communication patterns and their intracellular information flow in synovial fibroblastic osteoarthritis and rheumatoid arthritis., PMID:37704178
Identification and analysis of RNA-5-methylcytosine-related key genes in osteoarthritis., PMID:37700248
Combined sequence and copy number analysis improves diagnosis of limb girdle and other myopathies., PMID:37688281
The UCMD-Causing COL6A1 (c.930 + 189C > T) Intron Mutation Leads to the Secretion and Aggregation of Single Mutated Collagen VI α1 Chains., PMID:40225172
For research use only. Not for human or drug use.
