Catalog No.
RHH32002
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
STX1A, STX1, Neuron-specific antigen HPC-1, Syntaxin-1A
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q16623
Applications
FCM, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2H24
Shiga Toxin (Stx) Type 1a and Stx2a Translocate through a Three-Layer Intestinal Model., PMID:36977098
Annexin A2 Flop-Out Mediates the Non-Vesicular Release of DAMPs/Alarmins from C6 Glioma Cells Induced by Serum-Free Conditions., PMID:33807671
Thin-Layer Chromatography in Structure and Recognition Studies of Shiga Toxin Glycosphingolipid Receptors., PMID:33704756
Rapid and Label-Free Immunosensing of Shiga Toxin Subtypes with Surface Plasmon Resonance Imaging., PMID:32357576
Shiga Toxin Type 1a (Stx1a) Reduces the Toxicity of the More Potent Stx2a In Vivo and In Vitro., PMID:30670557
Novel monoclonal antibodies against Stx1d and 1e and their use for improving immunoassays., PMID:28434982
Shiga toxin glycosphingolipid receptors and their lipid membrane ensemble in primary human blood-brain barrier endothelial cells., PMID:27558838
New Monoclonal Antibodies against a Novel Subtype of Shiga Toxin 1 Produced by Enterobacter cloacae and Their Use in Analysis of Human Serum., PMID:27303707
Phage-mediated Shiga toxin (Stx) horizontal gene transfer and expression in non-Shiga toxigenic Enterobacter and Escherichia coli strains., PMID:27109772
A New Immunoassay for Detecting All Subtypes of Shiga Toxins Produced by Shiga Toxin-Producing E. coli in Ground Beef., PMID:26824247
Oral intoxication of mice with Shiga toxin type 2a (Stx2a) and protection by anti-Stx2a monoclonal antibody 11E10., PMID:24379294
Amacrine cell subtypes differ in their intrinsic neurite growth capacity., PMID:24130183
Shiga toxin A subunit mutant of Escherichia coli O157:H7 releases outer membrane vesicles containing the B-pentameric complex., PMID:20199568
A Thy1-CFP DBA/2J mouse line with cyan fluorescent protein expression in retinal ganglion cells., PMID:19930759
Cyan fluorescent protein expression in ganglion and amacrine cells in a thy1-CFP transgenic mouse retina., PMID:18728756
Immune responses of mice immunized with active recombinant shiga toxin and its derivatives., PMID:18552406
Search for genetic variants of the SYNTAXIN 1A (STX1A) gene: the -352 A>T variant in the STX1A promoter associates with impaired glucose metabolism in an Italian obese population., PMID:17912268
Synaptic proteins and SNARE complexes are localized in lipid rafts from rat brain synaptosomes., PMID:15721282
Correlation of syntaxin-1 and SNAP-25 clusters with docking and fusion of insulin granules analysed by total internal reflection fluorescence microscopy., PMID:15647897
R-type voltage-gated Ca(2+) channel interacts with synaptic proteins and recruits synaptotagmin to the plasma membrane of Xenopus oocytes., PMID:15464290
Syntaxin/Munc18 interactions in the late events during vesicle fusion and release in exocytosis., PMID:15175344
A syntaxin 1, Galpha(o), and N-type calcium channel complex at a presynaptic nerve terminal: analysis by quantitative immunocolocalization., PMID:15102922
Reticulon 1-C/neuroendocrine-specific protein-C interacts with SNARE proteins., PMID:15086514
Rab27 effector granuphilin promotes the plasma membrane targeting of insulin granules via interaction with syntaxin 1a., PMID:15028737
Determinants of liposome fusion mediated by synaptic SNARE proteins., PMID:14981239
Evidence for structural and functional diversity among SDS-resistant SNARE complexes in neuroendocrine cells., PMID:14762114
Site of docking and fusion of insulin secretory granules in live MIN6 beta cells analyzed by TAT-conjugated anti-syntaxin 1 antibody and total internal reflection fluorescence microscopy., PMID:14676208
Glucose uptake in PC12 cells: GLUT3 vesicle trafficking and fusion as revealed with a novel GLUT3-GFP fusion protein., PMID:12898536
Immunolocalization of the acid-sensing ion channel 2a in the rat cerebellum., PMID:12768285
Identification of the carboxyl-terminal membrane-anchoring region of HPC-1/syntaxin 1A with the substituted-cysteine-accessibility method and monoclonal antibodies., PMID:12761168
Rapid apoptosis induced by Shiga toxin in HeLa cells., PMID:12704147
False interaction of syntaxin 1A with a Ca(2+)-activated K(+) channel revealed by co-immunoprecipitation and pull-down assays: implications for identification of protein-protein interactions., PMID:12681380
Effect of hypothyroidism on synaptosomal-associated protein of 25 kDa and syntaxin-1 expression in adenohypophyses of rat., PMID:12398231
D53 is a novel endosomal SNARE-binding protein that enhances interaction of syntaxin 1 with the synaptobrevin 2 complex in vitro., PMID:12376003
Cellular munc18c levels can modulate glucose transport rate and GLUT4 translocation in 3T3L1 cells., PMID:12297296
CFTR chloride channels are regulated by a SNAP-23/syntaxin 1A complex., PMID:12209004
Munc 18a binding to syntaxin 1A and 1B isoforms defines its localization at the plasma membrane and blocks SNARE assembly in a three-hybrid system assay., PMID:12093152
Abnormal synaptic protein expression and cell death in murine scrapie., PMID:12012094
Homotypic fusion of immature secretory granules during maturation requires syntaxin 6., PMID:11408578
Altered immunoreactivity of HPC-1/syntaxin 1A in proliferated nerve fibers in the human aganglionic colon of Hirschsprung's disease., PMID:11345516
Characterization of a transformed rat retinal ganglion cell line., PMID:11165366
Localization of cellubrevin-related peptide, endobrevin, in the early endosome in pancreatic beta cells and its physiological function in exo-endocytosis of secretory granules., PMID:11112705
A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function., PMID:11101518
Incorporation and differentiation of hippocampus-derived neural stem cells transplanted in injured adult rat retina., PMID:11095625
The SNARE Vti1a-beta is localized to small synaptic vesicles and participates in a novel SNARE complex., PMID:10908612
Antiviral activity of shiga toxin 1: suppression of bovine leukemia virus-related spontaneous lymphocyte proliferation., PMID:10899843
Phosphorylated syntaxin 1 is localized to discrete domains along a subset of axons., PMID:10844023
SNAP-25 regulation during adrenal gland development: comparison with differentiation markers and other SNAREs., PMID:10842212
Expression analysis and protein localization of the human HPC-1/syntaxin 1A, a gene deleted in Williams syndrome., PMID:10644452
Proteolysis of synaptobrevin, syntaxin, and SNAP-25 in alveolar epithelial type II cells., PMID:10632578
For research use only. Not for human or drug use.
