Catalog No.
RHG41702
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, WB: 1:1000-1:2000
Target
Nuclear receptor subfamily 1 group H member 3, Oxysterols receptor LXR-alpha, NR1H3, Liver X receptor alpha, LXRA
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q13133
Applications
FCM, IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2D88
Screening of key genes involved in endometritis in cows and the regulatory role of CD83 in bovine endometrial epithelial cells., PMID:39892172
LXRα agonist differentially regulates BAFF expression and biological effects in RAW264.7 cells depending on growth status: LXRα activation and BAFF signaling in RAW264.7 cells., PMID:39632295
Interrupting tumor necrosis factor-alpha signaling prevents parenteral nutrition-associated cholestasis in mice., PMID:34664730
Genome-wide Association Study Identifies 2 New Loci Associated With Anti-NMDAR Encephalitis., PMID:34584012
Liver X Receptor α in Sciatic Nerve Exerts an Alleviating Effect on Neuropathic Pain Behaviors Induced by Crush Injury., PMID:33200264
Activation of LXRs using the synthetic agonist GW3965 represses the production of pro-inflammatory cytokines by murine mast cells., PMID:26344074
Mer signaling increases the abundance of the transcription factor LXR to promote the resolution of acute sterile inflammation., PMID:25714463
Levels of liver X receptors in testicular biopsies of patients with azoospermia., PMID:24842676
Infliximab reverses suppression of cholesterol efflux proteins by TNF-α: a possible mechanism for modulation of atherogenesis., PMID:24587984
Effects of Alisma Decoction on lipid metabolism and inflammatory response are mediated through the activation of the LXRα pathway in macrophage-derived foam cells., PMID:24504056
Activation of soluble guanylyl cyclase prevents foam cell formation and atherosclerosis., PMID:24299003
Novel effect of paeonol on the formation of foam cells: promotion of LXRα-ABCA1-dependent cholesterol efflux in macrophages., PMID:24117070
Ligation of RAGE with ligand S100B attenuates ABCA1 expression in monocytes., PMID:23523156
Exercise-associated generation of PPARγ ligands activates PPARγ signaling events and upregulates genes related to lipid metabolism., PMID:22174394
Anti-atherogenic effect of berberine on LXRalpha-ABCA1-dependent cholesterol efflux in macrophages., PMID:20506155
Tryptase promotes human monocyte-derived macrophage foam cell formation by suppressing LXRalpha activation., PMID:20139031
Tumor-mediated liver X receptor-alpha activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses., PMID:20037595
Liver X receptors control IgE expression in B cells., PMID:19380774
Stromal growth and epithelial cell proliferation in ventral prostates of liver X receptor knockout mice., PMID:19122149
Liver X receptor-alpha regulates proopiomelanocortin (POMC) gene transcription in the pituitary., PMID:19036902
TLR/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis., PMID:18981139
C-reactive protein induces pro- and anti-inflammatory effects, including activation of the liver X receptor alpha, on human monocytes., PMID:18327405
Liver X receptor is a key regulator of cytokine release in human monocytes., PMID:17724434
Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors., PMID:17563384
Expression of liver X receptor alpha in rat fetal tissues at different developmental stages., PMID:17341476
Gene expression changes in foam cells and the role of chemokine receptor CCR7 during atherosclerosis regression in ApoE-deficient mice., PMID:16537455
Placental expression of the nuclear receptors for oxysterols LXRalpha and LXRbeta during mouse and human development., PMID:15674823
Expression of the LXRalpha protein in human atherosclerotic lesions., PMID:15625283
For research use only. Not for human or drug use.
