Catalog No.
RHG38101
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IP: 1:20, WB: 1:500-1:1000
Target
KRS2, STK4, MST1/N, MST1/C, MST1, MST-1, Serine/threonine-protein kinase 4, Mammalian STE20-like protein kinase 1, STE20-like kinase MST1, Serine/threonine-protein kinase Krs-2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q13043
Applications
IF, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2D69
Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing., PMID:39381601
A unique STK4 mutation truncating only the C-terminal SARAH domain results in a mild clinical phenotype despite severe T cell lymphopenia: Case report., PMID:38361950
Association Study between SNPs in MST1 and MST2 and H. pylori Infection as well as Noncardia Gastric Carcinogenesis., PMID:38295774
Mst1-mediated phosphorylation of Nur77 improves the endometrial receptivity in human and mice., PMID:36623453
Hematopoietic stem cell transplantation in serine/threonine kinase 4 (STK4) deficiency: Report of two cases and literature review., PMID:36394186
When to suspect inborn errors of immunity in Epstein-Barr virus-related lymphoproliferative disorders., PMID:36209991
Involvement of MST1/mTORC1/STAT1 activity in the regulation of B-cell receptor signalling by chemokine receptor 2., PMID:35875970
Primary Immune Regulatory Disorders With an Autoimmune Lymphoproliferative Syndrome-Like Phenotype: Immunologic Evaluation, Early Diagnosis and Management., PMID:34447369
A Novel STK4 Mutation Impairs T Cell Immunity Through Dysregulation of Cytokine-Induced Adhesion and Chemotaxis Genes., PMID:34427831
Diversity in Serine/Threonine Protein Kinase-4 Deficiency and Review of the Literature., PMID:34146746
Hippo-YAP signaling controls lineage differentiation of mouse embryonic stem cells through modulating the formation of super-enhancers., PMID:32510157
A case report of sinusoidal diffuse large B-cell lymphoma in a STK4 deficient patient., PMID:32118703
Hippo Pathway Kinase Mst1 Is Required for Long-Lived Humoral Immunity., PMID:30478091
The Mst1 Kinase Is Required for Follicular B Cell Homing and B-1 B Cell Development., PMID:30386341
The hippo pathway provides novel insights into lung cancer and mesothelioma treatment., PMID:30073421
Fv-clasp: An Artificially Designed Small Antibody Fragment with Improved Production Compatibility, Stability, and Crystallizability., PMID:28919443
Mapping the STK4/Hippo signaling network in prostate cancer cell., PMID:28880957
Successful Curative Therapy With Rituximab and Allogeneic Haematopoietic Stem Cell Transplantation for MALT Lymphoma Associated With STK4-Mutated CD4+ Lymphocytopenia., PMID:27163767
Development of a novel multiplex beads-based assay for autoantibody detection for colorectal cancer diagnosis., PMID:26915739
Hypermethylation of MST1 in IgG4-related autoimmune pancreatitis and rheumatoid arthritis., PMID:26056943
Spatiotemporal proteomic analyses during pancreas cancer progression identifies serine/threonine stress kinase 4 (STK4) as a novel candidate biomarker for early stage disease., PMID:25225358
Protein kinases paralleling late-phase LTP formation in dorsal hippocampus in the rat., PMID:24911953
Rescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers., PMID:24813251
Identification of MST1/STK4 and SULF1 proteins as autoantibody targets for the diagnosis of colorectal cancer by using phage microarrays., PMID:21228115
MAPKs and Mst1/Caspase-3 pathways contribute to H2B phosphorylation during UVB-induced apoptosis., PMID:20602268
Identification of tumor-associated autoantigens for the diagnosis of colorectal cancer in serum using high density protein microarrays., PMID:19638618
Histone modifications associated with somatic hypermutation., PMID:16039583
Caspase-catalyzed cleavage and activation of Mst1 correlates with eosinophil but not neutrophil apoptosis., PMID:11964314
MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation., PMID:11278283
For research use only. Not for human or drug use.
