Catalog No.
RHF92701
Species reactivity
Human, Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, WB: 1:1000-1:2000
Target
Contactin-2, TAX1, TAG1, Axonal glycoprotein TAG-1, TAX-1, Axonin-1, CNTN2, AXT, Transient axonal glycoprotein 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q02246
Applications
FCM, IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2C17
Anti-neurofascin-155 antibody mediated a distinct phenotype of chronic inflammatory demyelinating polyradiculoneuropathy., PMID:38771386
Characterization of the patients with antibodies against nodal-paranodal junction proteins in chronic inflammatory demyelinating polyneuropathy., PMID:36401951
Phosphacan acts as a repulsive cue in murine and rat cerebellar granule cells in a TAG-1/GD3 rafts-dependent manner., PMID:36227633
Characteristics of Anti-Contactin1 Antibody-Associated Autoimmune Nodopathies With Concomitant Membranous Nephropathy., PMID:34675937
Genetic biomarkers for intravenous immunoglobulin response in chronic inflammatory demyelinating polyradiculoneuropathy., PMID:33460483
Toxicogenomic analyses of the effects of BDE-47/209, TBBPA/S and TCBPA on early neural development with a human embryonic stem cell in vitro differentiation system., PMID:31326446
Impact of anti-CASPR2 autoantibodies from patients with autoimmune encephalitis on CASPR2/TAG-1 interaction and Kv1 expression., PMID:31176559
Association of Leucine-Rich Glioma Inactivated Protein 1, Contactin-Associated Protein 2, and Contactin 2 Antibodies With Clinical Features and Patient-Reported Pain in Acquired Neuromyotonia., PMID:30242309
Click Chemistry-mediated Biotinylation Reveals a Function for the Protease BACE1 in Modulating the Neuronal Surface Glycoproteome., PMID:29716987
Mechanisms of Caspr2 antibodies in autoimmune encephalitis and neuromyotonia., PMID:29244234
Nogo-B is the major form of Nogo at the floor plate and likely mediates crossing of commissural axons in the mouse spinal cord., PMID:28543060
Genome-wide linkage and exome analyses identify variants of HMCN1 for splenic epidermoid cyst., PMID:25338956
BACE1 activity regulates cell surface contactin-2 levels., PMID:24405708
Expanding the Ig superfamily code for laminar specificity in retina: expression and role of contactins., PMID:23055510
A clinico-radiological phenotype of voltage-gated potassium channel complex antibody-mediated disorder presenting with seizures and basal ganglia changes., PMID:22817763
Morvan syndrome: clinical and serological observations in 29 cases., PMID:22473710
Analysis of antibodies to surface epitopes of contactin-2 in multiple sclerosis., PMID:22245283
Morvan's syndrome associated with antibodies to multiple components of the voltage-gated potassium channel complex., PMID:21906755
The effects of Tag-1 on the maturation of mouse cerebellar granule neurons., PMID:21191645
Single nucleotide polymorphism of TAG-1 influences IVIg responsiveness of Japanese patients with CIDP., PMID:19776380
Predicting treatment responses to IV immunoglobulins: can we already ask the genes?, PMID:19776375
Structure-function analysis of protein complexes involved in the molecular architecture of juxtaparanodal regions of myelinated fibers., PMID:17405182
Distribution of OL-protocadherin in axon fibers in the developing chick nervous system., PMID:15836925
Distribution of RA175/TSLC1/SynCAM, a member of the immunoglobulin superfamily, in the developing nervous system., PMID:15707673
Morphological and molecular heterogeneity in release sites of single neurons., PMID:12713639
Differential non-target-derived repulsive signals play a critical role in shaping initial axonal growth of dorsal root ganglion neurons., PMID:12591248
Subpial neuronal migration in the medulla oblongata of Pax-6-deficient rats., PMID:12534968
Association of GPI-anchored protein TAG-1 with src-family kinase Lyn in lipid rafts of cerebellar granule cells., PMID:12374219
Analysis of interactions of the adhesion molecule TAG-1 and its domains with other immunoglobulin superfamily members., PMID:12139915
A combination of chain and neurophilic migration involving the adhesion molecule TAG-1 in the caudal medulla., PMID:11807022
A neuronal inhibitory domain in the N-terminal half of agrin., PMID:11793362
Axonin-1/TAG-1 mediates cell-cell adhesion by a cis-assisted trans-interaction., PMID:11733523
Identification and characterization of a cell surface marker for embryonic rat spinal accessory motor neurons., PMID:11596060
Immunoseparation of sphingolipid-enriched membrane domains enriched in Src family protein tyrosine kinases and in the neuronal adhesion molecule TAG-1 by anti-GD3 ganglioside monoclonal antibody., PMID:11553690
The gene for the axonal cell adhesion molecule TAX-1 is amplified and aberrantly expressed in malignant gliomas., PMID:11280781
TAG-1-deficient mice have marked elevation of adenosine A1 receptors in the hippocampus., PMID:11178983
Involvement of gangliosides in glycosylphosphatidylinositol-anchored neuronal cell adhesion molecule TAG-1 signaling in lipid rafts., PMID:10944523
Human T-cell lymphotropic virus type 1-infected T lymphocytes impair catabolism and uptake of glutamate by astrocytes via Tax-1 and tumor necrosis factor alpha., PMID:10864655
A direct interaction of axonin-1 with NgCAM-related cell adhesion molecule (NrCAM) results in guidance, but not growth of commissural axons., PMID:10811834
Ventrally located commissural neurons express the GABAergic phenotype in developing rat spinal cord., PMID:10379921
Nr-CAM promotes neurite outgrowth from peripheral ganglia by a mechanism involving axonin-1 as a neuronal receptor., PMID:10328925
Sustained delivery of immunoglobulins from polymer microsources on a narrow surface of the developing rat brain., PMID:9821629
Immunohistochemical analysis of developmental stage of external granular layer neurons which undergo apoptosis in postnatal rat cerebellum., PMID:9533400
The fibronectin domains of the neural adhesion molecule TAX-1 are necessary and sufficient for homophilic binding., PMID:8910580
Novel neural adhesion molecules in the Contactin/F3 subgroup of the immunoglobulin superfamily: isolation and characterization of cDNAs from rat brain., PMID:8945756
TAG-1/axonin-1 is a high-affinity ligand of neurocan, phosphacan/protein-tyrosine phosphatase-zeta/beta, and N-CAM., PMID:8663515
Binding between the neural cell adhesion molecules axonin-1 and Nr-CAM/Bravo is involved in neuron-glia interaction., PMID:7490283
Overlapping and differential expression of BIG-2, BIG-1, TAG-1, and F3: four members of an axon-associated cell adhesion molecule subgroup of the immunoglobulin superfamily., PMID:8586965
Axonin-1, Nr-CAM, and Ng-CAM play different roles in the in vivo guidance of chick commissural neurons., PMID:7541632
Distribution of TAG-1/axonin-1 in fibre tracts and migratory streams of the developing mouse nervous system., PMID:8089271
For research use only. Not for human or drug use.
