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Anti-CNTN2/TAG1 Antibody (R2C17)

Catalog #:   RHF92701 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: FCM, IF, WB
Accession: Q02246
Overview

Catalog No.

RHF92701

Species reactivity

Human, Mouse

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

FCM: 1:20-1:100, IF: 1:50-1:200, WB: 1:1000-1:2000

Target

Contactin-2, TAX1, TAG1, Axonal glycoprotein TAG-1, TAX-1, Axonin-1, CNTN2, AXT, Transient axonal glycoprotein 1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q02246

Applications

FCM, IF, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R2C17

Data Image
  • Western blot
    Western blot analysis of TAG1 expression in U87-MG cell lysate.
References

Anti-neurofascin-155 antibody mediated a distinct phenotype of chronic inflammatory demyelinating polyradiculoneuropathy., PMID:38771386

Characterization of the patients with antibodies against nodal-paranodal junction proteins in chronic inflammatory demyelinating polyneuropathy., PMID:36401951

Phosphacan acts as a repulsive cue in murine and rat cerebellar granule cells in a TAG-1/GD3 rafts-dependent manner., PMID:36227633

Characteristics of Anti-Contactin1 Antibody-Associated Autoimmune Nodopathies With Concomitant Membranous Nephropathy., PMID:34675937

Genetic biomarkers for intravenous immunoglobulin response in chronic inflammatory demyelinating polyradiculoneuropathy., PMID:33460483

Toxicogenomic analyses of the effects of BDE-47/209, TBBPA/S and TCBPA on early neural development with a human embryonic stem cell in vitro differentiation system., PMID:31326446

Impact of anti-CASPR2 autoantibodies from patients with autoimmune encephalitis on CASPR2/TAG-1 interaction and Kv1 expression., PMID:31176559

Association of Leucine-Rich Glioma Inactivated Protein 1, Contactin-Associated Protein 2, and Contactin 2 Antibodies With Clinical Features and Patient-Reported Pain in Acquired Neuromyotonia., PMID:30242309

Click Chemistry-mediated Biotinylation Reveals a Function for the Protease BACE1 in Modulating the Neuronal Surface Glycoproteome., PMID:29716987

Mechanisms of Caspr2 antibodies in autoimmune encephalitis and neuromyotonia., PMID:29244234

Nogo-B is the major form of Nogo at the floor plate and likely mediates crossing of commissural axons in the mouse spinal cord., PMID:28543060

Genome-wide linkage and exome analyses identify variants of HMCN1 for splenic epidermoid cyst., PMID:25338956

BACE1 activity regulates cell surface contactin-2 levels., PMID:24405708

Expanding the Ig superfamily code for laminar specificity in retina: expression and role of contactins., PMID:23055510

A clinico-radiological phenotype of voltage-gated potassium channel complex antibody-mediated disorder presenting with seizures and basal ganglia changes., PMID:22817763

Morvan syndrome: clinical and serological observations in 29 cases., PMID:22473710

Analysis of antibodies to surface epitopes of contactin-2 in multiple sclerosis., PMID:22245283

Morvan's syndrome associated with antibodies to multiple components of the voltage-gated potassium channel complex., PMID:21906755

The effects of Tag-1 on the maturation of mouse cerebellar granule neurons., PMID:21191645

Single nucleotide polymorphism of TAG-1 influences IVIg responsiveness of Japanese patients with CIDP., PMID:19776380

Predicting treatment responses to IV immunoglobulins: can we already ask the genes?, PMID:19776375

Structure-function analysis of protein complexes involved in the molecular architecture of juxtaparanodal regions of myelinated fibers., PMID:17405182

Distribution of OL-protocadherin in axon fibers in the developing chick nervous system., PMID:15836925

Distribution of RA175/TSLC1/SynCAM, a member of the immunoglobulin superfamily, in the developing nervous system., PMID:15707673

Morphological and molecular heterogeneity in release sites of single neurons., PMID:12713639

Differential non-target-derived repulsive signals play a critical role in shaping initial axonal growth of dorsal root ganglion neurons., PMID:12591248

Subpial neuronal migration in the medulla oblongata of Pax-6-deficient rats., PMID:12534968

Association of GPI-anchored protein TAG-1 with src-family kinase Lyn in lipid rafts of cerebellar granule cells., PMID:12374219

Analysis of interactions of the adhesion molecule TAG-1 and its domains with other immunoglobulin superfamily members., PMID:12139915

A combination of chain and neurophilic migration involving the adhesion molecule TAG-1 in the caudal medulla., PMID:11807022

A neuronal inhibitory domain in the N-terminal half of agrin., PMID:11793362

Axonin-1/TAG-1 mediates cell-cell adhesion by a cis-assisted trans-interaction., PMID:11733523

Identification and characterization of a cell surface marker for embryonic rat spinal accessory motor neurons., PMID:11596060

Immunoseparation of sphingolipid-enriched membrane domains enriched in Src family protein tyrosine kinases and in the neuronal adhesion molecule TAG-1 by anti-GD3 ganglioside monoclonal antibody., PMID:11553690

The gene for the axonal cell adhesion molecule TAX-1 is amplified and aberrantly expressed in malignant gliomas., PMID:11280781

TAG-1-deficient mice have marked elevation of adenosine A1 receptors in the hippocampus., PMID:11178983

Involvement of gangliosides in glycosylphosphatidylinositol-anchored neuronal cell adhesion molecule TAG-1 signaling in lipid rafts., PMID:10944523

Human T-cell lymphotropic virus type 1-infected T lymphocytes impair catabolism and uptake of glutamate by astrocytes via Tax-1 and tumor necrosis factor alpha., PMID:10864655

A direct interaction of axonin-1 with NgCAM-related cell adhesion molecule (NrCAM) results in guidance, but not growth of commissural axons., PMID:10811834

Ventrally located commissural neurons express the GABAergic phenotype in developing rat spinal cord., PMID:10379921

Nr-CAM promotes neurite outgrowth from peripheral ganglia by a mechanism involving axonin-1 as a neuronal receptor., PMID:10328925

Sustained delivery of immunoglobulins from polymer microsources on a narrow surface of the developing rat brain., PMID:9821629

Immunohistochemical analysis of developmental stage of external granular layer neurons which undergo apoptosis in postnatal rat cerebellum., PMID:9533400

The fibronectin domains of the neural adhesion molecule TAX-1 are necessary and sufficient for homophilic binding., PMID:8910580

Novel neural adhesion molecules in the Contactin/F3 subgroup of the immunoglobulin superfamily: isolation and characterization of cDNAs from rat brain., PMID:8945756

TAG-1/axonin-1 is a high-affinity ligand of neurocan, phosphacan/protein-tyrosine phosphatase-zeta/beta, and N-CAM., PMID:8663515

Binding between the neural cell adhesion molecules axonin-1 and Nr-CAM/Bravo is involved in neuron-glia interaction., PMID:7490283

Overlapping and differential expression of BIG-2, BIG-1, TAG-1, and F3: four members of an axon-associated cell adhesion molecule subgroup of the immunoglobulin superfamily., PMID:8586965

Axonin-1, Nr-CAM, and Ng-CAM play different roles in the in vivo guidance of chick commissural neurons., PMID:7541632

Distribution of TAG-1/axonin-1 in fibre tracts and migratory streams of the developing mouse nervous system., PMID:8089271

Datasheet
$ 290
Product specifications
50 μg 290 100 μg 484

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For research use only. Not for human or drug use.

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Anti-CNTN2/TAG1 Antibody (R2C17) [RHF92701]
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