Catalog No.
RHF92002
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
PRKCE, PKCE, nPKC-epsilon, Protein kinase C epsilon type
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q02156
Applications
FCM, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2C12
Activated Protein Kinase C (PKC) Is Persistently Trafficked with Epidermal Growth Factor (EGF) Receptor., PMID:32906765
SHORT syndrome due to a novel de novo mutation in PRKCE (Protein Kinase Cɛ) impairing TORC2-dependent AKT activation., PMID:28934384
PKC-epsilon and TLR4 synergistically regulate resistin-mediated inflammation in human macrophages., PMID:28286252
PKCε-CREB-Nrf2 signalling induces HO-1 in the vascular endothelium and enhances resistance to inflammation and apoptosis., PMID:25883219
Antiphospholipid Antibodies Alter Cell-Death-Regulating Lipid Metabolites in First and Third Trimester Human Placentae., PMID:25856778
c-Abl modulates tumor cell sensitivity to antibody-dependent cellular cytotoxicity., PMID:25300860
T/B-cell interactions are more transient in response to weak stimuli in SLE-prone mice., PMID:25209945
Expression of Ser729 phosphorylated PKCepsilon in experimental crescentic glomerulonephritis: an immunohistochemical study., PMID:24998921
Rho kinase acts as a downstream molecule to participate in protein kinase Cε regulation of vascular reactivity after hemorrhagic shock in rats., PMID:24827390
Transcriptomic analysis of placenta affected by antiphospholipid antibodies: following the TRAIL of trophoblast death., PMID:22542907
Matrix metalloproteinases modulated by protein kinase Cε mediate resistin-induced migration of human coronary artery smooth muscle cells., PMID:21277149
The development of activating and inhibiting camelid VHH domains against human protein kinase C epsilon., PMID:21220006
Chronic stress sensitizes rats to pancreatitis induced by cerulein: role of TNF-α., PMID:21105189
Protease-activated receptor 2-mediated protection of myocardial ischemia-reperfusion injury: role of transient receptor potential vanilloid receptors., PMID:19812353
Diverse roles for protein kinase C delta and protein kinase C epsilon in the generation of high-fat-diet-induced glucose intolerance in mice: regulation of lipogenesis by protein kinase C delta., PMID:19809797
Sequential activation of protein kinase C isoforms by organic dust is mediated by tumor necrosis factor., PMID:19635931
Opposite effects of protein kinase C beta1 (PKCbeta1) and PKCepsilon in the metastatic potential of a breast cancer murine model., PMID:19132529
Increased sensitivity of desensitized TRPV1 by PMA occurs through PKCepsilon-mediated phosphorylation at S800., PMID:16564619
Nutrient regulation of PKCepsilon is mediated by leucine, not insulin, in skeletal muscle., PMID:15886222
Endothelin-1 regulates protein kinase C isoforms differently in smooth muscle cells and in cardiomyocytes., PMID:15838306
Protein kinase C epsilon regulates tumor necrosis factor-alpha-induced stannin gene expression., PMID:15798003
Protein kinase C isozymes in hypertension and hypertrophy: insight from SHHF rat hearts., PMID:15792354
The noble gas xenon induces pharmacological preconditioning in the rat heart in vivo via induction of PKC-epsilon and p38 MAPK., PMID:15644876
Protein kinase Cepsilon is dispensable for TCR/CD3-signaling., PMID:15589318
Identification of the linker histone H1 as a protein kinase Cepsilon-binding protein in vascular smooth muscle., PMID:15499382
Mechanism of oleic acid-induced gap junctional disassembly in rat cardiomyocytes., PMID:15350848
Protein kinase C-alpha-induced hypertrophy of neonatal rat ventricular myocytes., PMID:15271671
Phorbol ester-induced translocation of PKC epsilon to the nucleus in fibroblasts: identification of nuclear PKC epsilon-associating proteins., PMID:15251432
G protein-coupled receptor-mediated phosphorylation of the activation loop of protein kinase D: dependence on plasma membrane translocation and protein kinase Cepsilon., PMID:15190080
Protein kinase Cdelta as gonadotropin-releasing hormone target isoenzyme in the alphaT3-1 gonadotrope cell line., PMID:15153754
Protein phosphorylation of human brain glutamic acid decarboxylase (GAD)65 and GAD67 and its physiological implications., PMID:15147202
Integrin signaling in inflammatory and neuropathic pain in the rat., PMID:14984413
State-specific monoclonal antibodies identify an intermediate state in epsilon protein kinase C activation., PMID:14761958
Differential implication of protein kinase C isoforms in cytotoxic T lymphocyte degranulation and TCR-induced Fas ligand expression., PMID:14645153
Kinome analysis of host response to mycobacterial infection: a novel technique in proteomics., PMID:14500469
Differential and regulated binding of cAMP-dependent protein kinase and protein kinase C isoenzymes to gravin in human model neurons: Evidence that gravin provides a dynamic platform for the localization for kinases during neuronal development., PMID:12857743
Activation of focal adhesion kinase by protein kinase C epsilon in neonatal rat ventricular myocytes., PMID:12829427
Protein kinase C isoforms in the enteric nervous system., PMID:12811573
State-dependent phosphorylation of epsilon-isozyme of protein kinase C in adult rat dorsal root ganglia after inflammation and nerve injury., PMID:12694383
The second phase activation of protein kinase C delta at late G1 is required for DNA synthesis in serum-induced cell cycle progression., PMID:12653960
Alterations in protein kinase C isoenzyme expression and autophosphorylation during the progression of pressure overload-induced left ventricular hypertrophy., PMID:12619877
A role for PKC-epsilon in Fc gammaR-mediated phagocytosis by RAW 264.7 cells., PMID:12499353
Association of protein kinase C with GABA(A) receptors containing alpha1 and alpha4 subunits in the cerebral cortex: selective effects of chronic ethanol consumption., PMID:12091471
Activation and phosphatidylinositol 3-kinase-dependent phosphorylation of protein kinase C-epsilon by the B cell antigen receptor., PMID:12036603
PKC epsilon is associated with myosin IIA and actin in fibroblasts., PMID:11897493
NK-active cytokines IL-2, IL-12, and IL-15 selectively modulate specific protein kinase C (PKC) isoforms in primary human NK cells., PMID:11788941
Isoform-specific membrane translocation of protein kinase C after ischemic preconditioning., PMID:11700956
B-cell receptor- and phorbol ester-induced NF-kappaB and c-Jun N-terminal kinase activation in B cells requires novel protein kinase C's., PMID:11533251
Regulation of ATP-sensitive K(+) channels by protein kinase C in murine colonic myocytes., PMID:11502563
Cis-polyunsaturated fatty acids stimulate beta1 integrin-mediated adhesion of human breast carcinoma cells to type IV collagen by activating protein kinases C-epsilon and -mu., PMID:11289113
For research use only. Not for human or drug use.
