Catalog No.
RHF88101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:50-1:100, WB: 1:500-1:1000
Target
DSPA2b, Interferon-inducible protein 1-8U, Interferon-induced transmembrane protein 3, IFITM3, Dispanin subfamily A member 2b
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q01628
Applications
IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2B97
IFITM3 deficient mice as a model for testing influenza virus vaccines., PMID:40501891
Attenuation of IFITM proteins' antiviral activity through sequestration into intraluminal vesicles of late endosomes., PMID:40501618
IFITM3 variants point to a critical role in emergent virus infections., PMID:40237465
Transcriptomic signatures in peripheral CD4+T-lymphocytes may reflect melanoma staging and immunotherapy responsiveness prior to ICI initiation., PMID:40226614
Upregulation of interferon-γ response genes in monocytes and T cells identified by single-cell transcriptomics in patients with anti-citrullinated peptide antibody-positive early rheumatoid arthritis., PMID:39877346
PGRN Inhibits Early B-cell Activation and IgE Production Through the IFITM3-STAT1 Signaling Pathway in Asthma., PMID:39412083
Altered platelet-megakaryocyte endocytosis and trafficking of albumin and fibrinogen in RUNX1 haplodeficiency., PMID:38330198
SP-R210 isoforms of Myosin18A modulate endosomal sorting and recognition of influenza A virus infection in macrophages., PMID:38135024
The truncated IFITM3 facilitates the humoral immune response in inactivated influenza vaccine-vaccinated mice via interaction with CD81., PMID:37556756
Influence of the Single Nucleotide Polymorphisms rs12252 and rs34481144 in IFITM3 on the Antibody Response after Vaccination against COVID-19., PMID:37515072
Comparison of a Genotype 1 and a Genotype 2 Macaque Foamy Virus env Gene Indicates Distinct Infectivity and Cell-Cell Fusion but Similar Tropism and Restriction of Cell Entry by Interferon-Induced Transmembrane Proteins., PMID:36851478
Determining the Protective Efficacy of Toll-Like Receptor Ligands to Minimize H9N2 Avian Influenza Virus Transmission in Chickens., PMID:36680279
Isolation of female germline stem cells from neonatal piglet ovarian tissue and differentiation into oocyte-like cells., PMID:36525858
Role of PCIF1-mediated 5'-cap N6-methyladeonsine mRNA methylation in colorectal cancer and anti-PD-1 immunotherapy., PMID:36514940
The P681H Mutation in the Spike Glycoprotein of the Alpha Variant of SARS-CoV-2 Escapes IFITM Restriction and Is Necessary for Type I Interferon Resistance., PMID:36350154
FLT3LG and IFITM3P6 consolidate T cell activity in the bone marrow microenvironment and are prognostic factors in acute myelocytic leukemia., PMID:36081495
Development of a chicken interferon-induced transmembrane protein 3 (IFITM3)-specific monoclonal antibody using phage display., PMID:35895533
SARS-CoV-2 Variants of Concern Hijack IFITM2 for Efficient Replication in Human Lung Cells., PMID:35543509
Enhanced method to select human oogonial stem cells for fertility research., PMID:34415395
IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro., PMID:34321474
Placental response to maternal SARS-CoV-2 infection., PMID:34257394
IFITM3 incorporation sensitizes influenza A virus to antibody-mediated neutralization., PMID:33882122
Escape of HIV-1 envelope glycoprotein from the restriction of infection by IFITM3., PMID:33298540
IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells., PMID:33149299
IFITM3-specific antibody reveals IFN preferences and slow IFN induction of the antiviral factor IFITM3 in humans., PMID:33125710
IFITM3 affects the level of antibody response after influenza vaccination., PMID:32321380
Explore the potential effect of natural herbals to resist Newcastle Disease Virus., PMID:30566670
High Level Antibody Response to Pandemic Influenza H1N1/09 Virus Is Associated With Interferon-Induced Transmembrane Protein-3 rs12252-CC in Young Adults., PMID:29868492
Characterization of migratory primordial germ cells in the aorta-gonad-mesonephros of a 4.5-week-old human embryo: a toolbox to evaluate in vitro early gametogenesis., PMID:29528446
BCL6 represses antiviral resistance in follicular T helper cells., PMID:28550121
Localization and distribution of gonadal proteins in the oviparous lizard Sceloporus aeneus (Squamata: Phrynosomatidae)., PMID:28515008
The V3 Loop of HIV-1 Env Determines Viral Susceptibility to IFITM3 Impairment of Viral Infectivity., PMID:28100616
Resistance of Transmitted Founder HIV-1 to IFITM-Mediated Restriction., PMID:27640936
Isolation of Mammalian Oogonial Stem Cells by Antibody-Based Fluorescence-Activated Cell Sorting., PMID:27557587
Induction of interferon-induced transmembrane protein 3 gene expression by lipopolysaccharide in astrocytes., PMID:25218983
A membrane topology model for human interferon inducible transmembrane protein 1., PMID:25105503
Interferon-induced transmembrane protein 3 is a type II transmembrane protein., PMID:24067232
Interferon-induced transmembrane protein-3 genetic variant rs12252-C is associated with severe influenza in Chinese individuals., PMID:23361009
For research use only. Not for human or drug use.
