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Research Grade Manelimab (DHJ70107)

Host species:Human
Isotype:IgG1-lambda
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHJ70107

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG1-lambda

Clonality

Monoclonal

Target

B7-H1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, PDCD1L1, B7 homolog 1, PDCD1LG1, PDL1, hPD-L1, Programmed death ligand 1, B7H1, PD-L1, CD274

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9NZQ7

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

BCD-135, CAS: 2168561-26-8

Clone ID

Manelimab

Data Image
  • SDS-PAGE
    SDS PAGE for Manelimab
  • Bioactivity
    Detects CD274/PD-L1/B7-H1 in indirect ELISAs.
References

Neoantigen-directed immune escape in lung cancer evolution, PMID: 30894752

Geospatial immune variability illuminates differential evolution of lung adenocarcinoma, PMID: 32461698

Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer, PMID: 31591606

A clonal expression biomarker associates with lung cancer mortality, PMID: 31591602

Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution, PMID: 32139907

Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse, PMID: 31591595

Etonogestrel concentrations among contraceptive implant users in Botswana using and not using dolutegravir-based antiretroviral therapy, PMID: 32387328

Dolutegravir Use at Conception - Additional Surveillance Data from Botswana, PMID: 31329378

Sanitation and Hygiene Practices in Small Towns in Tanzania: The Case of Babati District, Manyara Region, PMID: 32815501

Publisher Correction: A clonal expression biomarker associates with lung cancer mortality, PMID: 32494065

Publisher Correction: Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse, PMID: 32494064

Malaria risk factors in north-east Tanzania, PMID: 21507217

Publisher Correction: Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer, PMID: 32494063

Closing the Gap: Ensuring Access to and Quality of Contraceptive Implant Removal Services is Essential to Rights-based Contraceptive Care, PMID: 32227736

Explaining progress towards Millennium Development Goal 4 for child survival in Tanzania, PMID: 30643633

3D mosquito screens to create window double screen traps for mosquito control, PMID: 28851461

Effect of physicochemical parameters on Anopheles and Culex mosquito larvae abundance in different breeding sites in a rural setting of Muheza, Tanzania, PMID: 28645303

Ripple effects of research capacity strengthening: a study of the effects of a project to support test facilities in three African countries towards Good Laboratory Practice certification, PMID: 34124586

Distribution and spread of pyrethroid and DDT resistance among the Anopheles gambiae complex in Tanzania, PMID: 24192019

Susceptibility status of malaria vectors to insecticides commonly used for malaria control in Tanzania, PMID: 22519840

Experimental hut evaluation of a novel long-lasting non-pyrethroid durable wall lining for control of pyrethroid-resistant Anopheles gambiae and Anopheles funestus in Tanzania, PMID: 28212636

Knowledge of danger signs during pregnancy and subsequent healthcare seeking actions among women in Urban Tanzania: a cross-sectional study, PMID: 29295710

Pilot safety study of intrabronchial instillation of bone marrow-derived mononuclear cells in patients with silicosis, PMID: 26059242

Insecticide-treated net wall hangings for malaria vector control: an experimental hut study in north-eastern Tanzania, PMID: 25231168

Species shifts in the Anopheles gambiae complex: do LLINs successfully control Anopheles arabiensis?, PMID: 22438864

Larvicidal and mosquitocidal extracts, a coumarin, isoflavonoids and pterocarpans from Neorautanenia mitis, PMID: 15186932

Risk and protective factors for relapse among individuals with schizophrenia: a qualitative study in Dar es Salaam, Tanzania, PMID: 25168715

Spatial abundance and human biting rate of Anopheles arabiensis and Anopheles funestus in savannah and rice agro-ecosystems of Central Tanzania, PMID: 26054517

Effect of 1997-98 El Niño on highland malaria in Tanzania, PMID: 10768443

Seropositivity of Brucella spp. and Leptospira spp. antibodies among abattoir workers and meat vendors in the city of Mwanza, Tanzania: A call for one health approach control strategies, PMID: 29939991

Development and application of tools to cost the delivery of environmental health services in healthcare facilities: a financial analysis in urban Malawi, PMID: 33849531

Altitude-dependent and -independent variations in Plasmodium falciparum prevalence in northeastern Tanzania, PMID: 15838785

An experimental hut evaluation of Olyset nets against anopheline mosquitoes after seven years use in Tanzanian villages, PMID: 18307802

Estimating medium- and long-term trends in malaria transmission by using serological markers of malaria exposure, PMID: 15792998

Accessibility, availability and utilisation of malaria interventions among women of reproductive age in Kilosa district in central Tanzania, PMID: 25277956

Patterns of malaria related mortality based on verbal autopsy in Muleba District, north-western Tanzania, PMID: 20734701

Behavioural and insecticidal effects of organophosphate-, carbamate- and pyrethroid-treated mosquito nets against African malaria vectors, PMID: 19941597

The silent HIV epidemic among pregnant women within rural Northern Tanzania, PMID: 16643653

Evaluation of ICON Maxx, a long-lasting treatment kit for mosquito nets: experimental hut trials against anopheline mosquitoes in Tanzania, PMID: 26025026

Evaluation of the long-lasting insecticidal net Interceptor LN: laboratory and experimental hut studies against anopheline and culicine mosquitoes in northeastern Tanzania, PMID: 24499488

Interceptor® long-lasting insecticidal net: phase III evaluation over three years of household use and calibration with Phase II experimental hut outcomes, PMID: 27075874

HIV-1, HSV-2 and syphilis among pregnant women in a rural area of Tanzania: prevalence and risk factors, PMID: 18513451

Low mortality risk but high loss to follow-up among patients in the Tanzanian national HIV care and treatment programme, PMID: 22296265

Comparative efficacies of permethrin-, deltamethrin- and alpha-cypermethrin-treated nets, against Anopheles arabiensis and Culex quinquefasciatus in northern Tanzania, PMID: 18510817

The effectiveness of non-pyrethroid insecticide-treated durable wall lining to control malaria in rural Tanzania: study protocol for a two-armed cluster randomized trial, PMID: 27456339

Multi-country field trials comparing wash-resistance of PermaNet and conventional insecticide-treated nets against anopheline and culicine mosquitoes, PMID: 15752180

Malaria, anaemia and nutritional status among schoolchildren in relation to ecosystems, livelihoods and health systems in Kilosa District in central Tanzania, PMID: 26082157

Social determinants of malaria and health care seeking patterns among rice farming and pastoral communities in Kilosa District in central Tanzania, PMID: 25596436

Knowledge, attitudes and practices about malaria among communities: comparing epidemic and non-epidemic prone communities of Muleba district, North-western Tanzania, PMID: 20602778

Efficacy of pyrethroid-treated nets against malaria vectors and nuisance-biting mosquitoes in Tanzania in areas with long-term insecticide-treated net use, PMID: 17875017

Datasheet

Document Download

Research Grade Manelimab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

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Research Grade Manelimab [DHJ70107]
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