Catalog No.
YHC82101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr34-Pro128
Predicted molecular weight
13.13 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P10620
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MGST, Microsomal GST-I, MGST1, Microsomal GST-1, GST12, Microsomal glutathione S-transferase 1
Microsomal glutathione transferase 1 confers cisplatin resistance of non-small cell lung cancer via interaction with arachidonate lipoxygenase 5 to repress ferroptosis., PMID:39850123
MGST1 May Regulate the Ferroptosis of the Annulus Fibrosus of Intervertebral Disc: Bioinformatic Integrated Analysis and Validation., PMID:38940022
A role for microsomal glutathione transferase 1 in melanin biosynthesis and melanoma progression., PMID:37321450
Microsomal glutathione S-transferase 1 targets the autophagy signaling pathway to suppress ferroptosis in gastric carcinoma cells., PMID:37161854
MiR-379-5p targets microsomal glutathione transferase 1 (MGST1) to regulate human glioma in cell proliferation, migration and invasion and epithelial-mesenchymal transition (EMT)., PMID:34171541
MGST1 is a redox-sensitive repressor of ferroptosis in pancreatic cancer cells., PMID:33539732
Gene-by-gene interactions associated with the risk of conotruncal heart defects., PMID:31851787
Knockdown of microsomal glutathione S-transferase 1 inhibits lung adenocarcinoma cell proliferation and induces apoptosis., PMID:31707341
Reactive Oxygen Species Scavenging Potential Contributes to Hypertrophic Scar Formation., PMID:31302330
Role of AccMGST1 in oxidative stress resistance in Apis cerana cerana., PMID:31175533
Acute inhalation co-exposure to 1,2-dichloropropane and dichloromethane cause liver damage by inhibiting mitochondrial respiration and defense ability in mice., PMID:30240022
MGST1, a GSH transferase/peroxidase essential for development and hematopoietic stem cell differentiation., PMID:29702404
Establishment and Characteristics of a Novel Mantle Cell Lymphoma-derived Cell Line and a Bendamustine-resistant Subline., PMID:29695404
[Development of a Fluorescence Probe for Live Cell Imaging]., PMID:29093368
DCF1 subcellular localization and its function in mitochondria., PMID:29074393
Dead-end complex, lipid interactions and catalytic mechanism of microsomal glutathione transferase 1, an electron crystallography and mutagenesis investigation., PMID:28801553
Global Kinetic Mechanism of Microsomal Glutathione Transferase 1 and Insights into Dynamic Enzyme Activation., PMID:28558199
Molecular basis for the dual subcellular distribution of microsomal glutathione transferase 1., PMID:27913278
Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma., PMID:27486097
Sequence-based Association Analysis Reveals an MGST1 eQTL with Pleiotropic Effects on Bovine Milk Composition., PMID:27146958
Effect of static magnetic fields and phloretin on antioxidant defense system of human fibroblasts., PMID:27080405
Unaccounted uncertainty from qPCR efficiency estimates entails uncontrolled false positive rates., PMID:27067838
Effect of n-3 fatty acids on the expression of inflammatory genes in THP-1 macrophages., PMID:27044314
Genome-wide association analysis of milk yield traits in Nordic Red Cattle using imputed whole genome sequence variants., PMID:27006194
Lactococcus lactis is an Efficient Expression System for Mammalian Membrane Proteins Involved in Liver Detoxification, CYP3A4, and MGST1., PMID:26961909
Identification of Acetaminophen Adducts of Rat Liver Microsomal Proteins using 2D-LC-MS/MS., PMID:26510387
Trimeric microsomal glutathione transferase 2 displays one third of the sites reactivity., PMID:26066610
Influence of dietary fatty acids on differentiation of human stromal vascular fraction preadipocytes., PMID:25967283
Absence of MGST1 mRNA and protein expression in human neuroblastoma cell lines and primary tissue., PMID:24486338
Downregulation of microsomal glutathione-S-transferase 1 modulates protective mechanisms in differentiated PC12 cells., PMID:24419913
Nanoparticle-directed sub-cellular localization of doxorubicin and the sensitization breast cancer cells by circumventing GST-mediated drug resistance., PMID:24210875
[Characteristics of microsomal phase II metabolic enzymes in mouse embryonic stem cell-derived liver tissue]., PMID:24167134
Shear stress activation of nuclear receptor PXR in endothelial detoxification., PMID:23878263
Quantitative analysis of SOD2, ALDH1A1 and MGST1 messenger ribonucleic acid in anterior lens epithelium of patients with pseudoexfoliation syndrome., PMID:23805041
Characterization of microsomal glutathione S-transferases MGST1, MGST2, and MGST3 in cynomolgus macaque., PMID:23785063
Nrf2 defense pathway: Experimental evidence for its protective role in epilepsy., PMID:23686862
The role of xenobotic metabolism MGST1 gene polymorphism in colorectal cancer patients., PMID:23314968
Mechanisms for epigallocatechin gallate induced inhibition of drug metabolizing enzymes in rat liver microsomes., PMID:23010222
MGST1 expression in serous ovarian carcinoma differs at various anatomic sites, but is unrelated to chemoresistance or survival., PMID:22652154
Microsomal glutathione transferase 1 protects against toxicity induced by silica nanoparticles but not by zinc oxide nanoparticles., PMID:22303956
Characterization of new potential anticancer drugs designed to overcome glutathione transferase mediated resistance., PMID:21851097
Role of MGST1 in reactive intermediate-induced injury., PMID:21633660
Microsomal glutathione transferase 1: mechanism and functional roles., PMID:21495795
Adaptation of microsomal glutathione transferase 1 in PC12 cells with modified PMCA isoforms composition., PMID:21280562
Increased expression of miR-34a and miR-93 in rat liver during aging, and their impact on the expression of Mgst1 and Sirt1., PMID:21216258
Multiple roles of microsomal glutathione transferase 1 in cellular protection: a mechanistic study., PMID:20727966
Inhibition of mitochondrial membrane bound-glutathione transferase by mitochondrial permeability transition inhibitors including cyclosporin A., PMID:20226794
[Effect of concanavalin A on expression of MAPEG mRNA in Balb/c mouse brain]., PMID:19504633
Role of microsomal glutathione transferase 1 in the mechanism-based biotransformation of glyceryl trinitrate in LLC-PK1 cells., PMID:19428324
Microsomal glutathione transferase 1 exhibits one-third-of-the-sites-reactivity towards glutathione., PMID:19416719
For research use only. Not for human or drug use.
