Anti-FOXA1 Antibody (R1Z36)

Catalog No.

RHF12502

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000

Target

HNF-3-alpha, Transcription factor 3A, TCF3A, HNF3A, HNF-3A, FOXA1, TCF-3A, Hepatocyte nuclear factor 3-alpha, Forkhead box protein A1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P55317

Applications

IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1Z36

The Influence of the Germline HSD3B1 Adrenal-Permissive Allele (c.1100 C) on the Somatic Alteration Landscape, the Transcriptome, and Immune Cell Infiltration in Prostate Cancer., PMID:40282446

Homologous recombination repair status in metastatic prostate cancer by next-generation sequencing and functional immunofluorescence., PMID:39914385

FOXA1 enhances antitumor immunity via repressing interferon-induced PD-L1 expression in nasopharyngeal carcinoma., PMID:39542656

FOXA1, induced by RC48, regulates HER2 transcription to enhance the tumorigenic capacity of lung cancer through PI3K/AKT pathway., PMID:39440051

FOXA1/CK7-positive Esophageal Squamous Cell Carcinoma with Aggressive Liver Metastasis., PMID:38569907

PROTACs in the Management of Prostate Cancer., PMID:37175108

PAK4 inhibition improves PD1 blockade immunotherapy in prostate cancer by increasing immune infiltration., PMID:36509363

Immunohistochemical evaluation of forkhead box A1 and EphA5 markers in serous ovarian carcinomas, and their impact on the clinical outcome of patients., PMID:36345952

Recombinant humanized IgG1 maintain liver triglyceride homeostasis through Arylacetamide deacetylase in ApoE-/- mice., PMID:35397394

Serum Autoantibodies against LRDD, STC1, and FOXA1 as Biomarkers in the Detection of Ovarian Cancer., PMID:35273656

Heterogeneity in NECTIN4 Expression Across Molecular Subtypes of Urothelial Cancer Mediates Sensitivity to Enfortumab Vedotin., PMID:34108177

FOXA1 and adaptive response determinants to HER2 targeted therapy in TBCRC 036., PMID:33980863

A four-antibody immunohistochemical panel can distinguish clinico-pathological clusters of urothelial carcinoma and reveals high concordance between primary tumor and lymph node metastases., PMID:33128085

Efficacy of neoadjuvant atezolizumab treatment in patients with advanced urothelial bladder cancer according to the BASQ classification: a study protocol for an open-label, two-cohort, phase II trial., PMID:33060077

NCOR1 may be a potential biomarker of a novel molecular subtype of prostate cancer., PMID:33058520

Greater utility of molecular subtype rather than epithelial-to-mesenchymal transition (EMT) markers for prognosis in high-risk non-muscle-invasive (HGT1) bladder cancer., PMID:32374509

Estrogen Receptor, Inflammatory, and FOXO Transcription Factors Regulate Expression of Myasthenia Gravis-Associated Circulating microRNAs., PMID:32153563

Overexpression of transcription factor Foxa1 and target genes remediate therapeutic protein production bottlenecks in Chinese hamster ovary cells., PMID:31956982

BACH1 Promotes Pancreatic Cancer Metastasis by Repressing Epithelial Genes and Enhancing Epithelial-Mesenchymal Transition., PMID:31919242

The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer., PMID:31644911

Clinical outcomes of muscle invasive bladder Cancer according to the BASQ classification., PMID:31500577

Gene Expression Profiling Reveals Distinct Molecular Subtypes of Esophageal Squamous Cell Carcinoma in Asian Populations., PMID:31048097

Factors Affecting Interindividual Variability of Hepatic UGT2B17 Protein Expression Examined Using a Novel Specific Monoclonal Antibody., PMID:30819787

Immunohistochemical expression analysis of the human fetal lower urogenital tract., PMID:30287094

Chemical Cocktails Enable Hepatic Reprogramming of Mouse Fibroblasts with a Single Transcription Factor., PMID:28757167

A study of FoxA1 expression in thyroid tumors., PMID:28546130

Transcriptome and Proteome Analyses of TNFAIP8 Knockdown Cancer Cells Reveal New Insights into Molecular Determinants of Cell Survival and Tumor Progression., PMID:27807832

Foxc1 Ablated Mice Are Anhidrotic and Recapitulate Features of Human Miliaria Sweat Retention Disorder., PMID:27592801

Altered Expression of the Transcription Factor Forkhead Box A1 (FOXA1) Is Associated With Poor Prognosis in Urothelial Carcinoma of the Upper Urinary Tract., PMID:27215483

Amplification of WHSC1L1 regulates expression and estrogen-independent activation of ERα in SUM-44 breast cancer cells and is associated with ERα over-expression in breast cancer., PMID:27005559

Nfib Regulates Transcriptional Networks That Control the Development of Prostatic Hyperplasia., PMID:26677878

Orc1 Binding to Mitotic Chromosomes Precedes Spatial Patterning during G1 Phase and Assembly of the Origin Recognition Complex in Human Cells., PMID:25784553

ChIP-exo signal associated with DNA-binding motifs provides insight into the genomic binding of the glucocorticoid receptor and cooperating transcription factors., PMID:25720775

The expression and correlation between the transcription factor FOXP1 and estrogen receptors in epithelial ovarian cancer., PMID:25500588

CMT: a constrained multi-level thresholding approach for ChIP-Seq data analysis., PMID:24736605

A secretory cell type develops alongside multiciliated cells, ionocytes and goblet cells, and provides a protective, anti-infective function in the frog embryonic mucociliary epidermis., PMID:24598166

Effect of a matrigel sandwich on endodermal differentiation of human embryonic stem cells., PMID:23719997

A strand specific high resolution normalization method for chip-sequencing data employing multiple experimental control measurements., PMID:22248020

Forkhead transcription factor FoxA1 regulates sweat secretion through Bestrophin 2 anion channel and Na-K-Cl cotransporter 1., PMID:22223659

Identification of primary gene targets of TFAP2C in hormone responsive breast carcinoma cells., PMID:20629094

Cooperative signaling between Wnt1 and integrin-linked kinase induces accelerated breast tumor development., PMID:20565980

Cortactin gene amplification and expression in breast cancer: a chromogenic in situ hybridisation and immunohistochemical study., PMID:20213079

Characterization of mouse embryonic stem cell differentiation into the pancreatic lineage in vitro by transcriptional profiling, quantitative RT-PCR and immunocytochemistry., PMID:19876843

Chromosome 14 transfer and functional studies identify a candidate tumor suppressor gene, mirror image polydactyly 1, in nasopharyngeal carcinoma., PMID:19667180

Association of GATA3, P53, Ki67 status and vascular peritumoral invasion are strongly prognostic in luminal breast cancer., PMID:19405945

BRCA1 and FOXA1 proteins coregulate the expression of the cell cycle-dependent kinase inhibitor p27(Kip1)., PMID:16331276

Expression and role of Foxa proteins in prostate cancer., PMID:16001449

Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissues., PMID:15567715

Expression of Foxa transcription factors in the developing and adult murine prostate., PMID:15389796

Expression of hepatocyte nuclear factor-3alpha in rat prostate, seminal vesicle, and bladder., PMID:9489767

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