Catalog No.
RHE46501
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000
Target
SD, RANGAP1, Ran GTPase-activating protein 1, RanGAP1, KIAA1835
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P46060
Applications
IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1W73
SUMO monoclonal antibodies vary in sensitivity, specificity, and ability to detect types of SUMO conjugate., PMID:36494414
Recruitment of Host Nuclear Pore Components to the Vicinity of Theileria Schizonts., PMID:32024710
SGK1 affects RAN/RANBP1/RANGAP1 via SP1 to play a critical role in pre-miRNA nuclear export: a new route of epigenomic regulation., PMID:28358001
ON 01910.Na inhibits growth of diffuse large B-cell lymphoma by cytoplasmic sequestration of sumoylated C-MYB/TRAF6 complex., PMID:27150054
PCGF2 negatively regulates arsenic trioxide-induced PML-RARA protein degradation via UBE2I inhibition in NB4 cells., PMID:27030546
Importin-β negatively regulates multiple aspects of mitosis including RANGAP1 recruitment to kinetochores., PMID:22331847
Tollip is a mediator of protein sumoylation., PMID:19198660
Regulation of Wnt signaling by the nuclear pore complex., PMID:18439914
The Nup358-RanGAP complex is required for efficient importin alpha/beta-dependent nuclear import., PMID:18305100
Chip-based analysis of SUMO (small ubiquitin-like modifier) conjugation to a target protein., PMID:16820290
The SUMO pathway is essential for nuclear integrity and chromosome segregation in mice., PMID:16326389
Roles of Ran-GTP and Ran-GDP in precursor vesicle recruitment and fusion during nuclear envelope assembly in a human cell-free system., PMID:11231159
A novel mammalian Smt3-specific isopeptidase 1 (SMT3IP1) localized in the nucleolus at interphase., PMID:11029585
Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3., PMID:10692421
SUMO-1 modification of the acute promyelocytic leukaemia protein PML: implications for nuclear localisation., PMID:9885291
A plant homolog of the neutrophil NADPH oxidase gp91phox subunit gene encodes a plasma membrane protein with Ca2+ binding motifs., PMID:9490748
Evidence for covalent modification of the nuclear dot-associated proteins PML and Sp100 by PIC1/SUMO-1., PMID:9412458
RanBP2 associates with Ubc9p and a modified form of RanGAP1., PMID:9108047
A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2., PMID:9019411
A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex., PMID:8978815
Direct and indirect association of the small GTPase ran with nuclear pore proteins and soluble transport factors: studies in Xenopus laevis egg extracts., PMID:8885229
For research use only. Not for human or drug use.
