Catalog No.
RHD51302
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
A1S9T, Ubiquitin-like modifier-activating enzyme 1, UBA1, Protein A1S9, UBE1, Ubiquitin-activating enzyme E1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P22314
Applications
FCM, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1S01
Unravelling VEXAS syndrome: shedding light on a recently recognised medical condition., PMID:40499953
Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, and Somatic (VEXAS) Syndrome: A Diagnostic and Therapeutic Conundrum., PMID:40130124
Altered IgG4 serum levels in VEXAS syndrome - a retrospective monocentric cohort study., PMID:40119917
UBA1 inhibition sensitizes cancer cells to PARP inhibitors., PMID:39626673
Expanding the VEXAS diagnostic workup: the role of peripheral blood cytological analysis., PMID:39421750
Novel use of Siltuximab in a patient with VEXAS Syndrome., PMID:39417832
Efficacy and safety of targeted therapies in VEXAS syndrome: retrospective study from the FRENVEX., PMID:38777378
Treatment experiences with focus on IL-6R inhibition in patients with VEXAS syndrome and a case of remission with azacytidine treatment., PMID:38141211
Sudden unexpected death of a young adult due to subarachnoid hemorrhage associated with polyarteritis nodosa: Clinicopathological appearance and literature review., PMID:38072093
Correlation analysis between auto-immunological and mutational profiles in myelodysplastic syndromes., PMID:37507570
Progress and challenges in the use of blood biomarkers in relapsing polychondritis., PMID:36751132
Case Report: Tocilizumab Treatment for VEXAS Syndrome With Relapsing Polychondritis: A Single-Center, 1-Year Longitudinal Observational Study In Japan., PMID:35769485
A case of VEXAS syndrome associated with EBV-associated hemophagocytic lymphohistiocytosis., PMID:34864445
Further characterization of clinical and laboratory features in VEXAS syndrome: large-scale analysis of a multicentre case series of 116 French patients., PMID:34632574
VEXAS Syndrome: A Case Series From a Single-Center Cohort of Italian Patients With Vasculitis., PMID:34611997
Tocilizumab in VEXAS relapsing polychondritis: a single-center pilot study in Japan., PMID:34260381
Somatic Mutation in UBA1 and ANCA-associated Vasculitis., PMID:34074684
Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer., PMID:29263404
TRPM8 channel as a novel molecular target in androgen-regulated prostate cancer cells., PMID:25980497
Stress effects caused by the expression of a mutant cellobiohydrolase I and proteasome inhibition in Trichoderma reesei Rut-C30., PMID:22877981
The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation., PMID:22797925
Ubiquitin-activating enzyme (UBA1) is required for sperm capacitation, acrosomal exocytosis and sperm-egg coat penetration during porcine fertilization., PMID:21950462
Microarray analyses uncover UBE1L as a candidate target gene for lung cancer chemoprevention., PMID:15520223
The Saccharomyces cerevisiae LOS1 gene involved in pre-tRNA splicing encodes a nuclear protein that behaves as a component of the nuclear matrix., PMID:8366091
Characterization of monoclonal antibodies directed against domains of pertussis toxin involved in receptor recognition., PMID:1724605
Cloning of ubiquitin activating enzyme from wheat and expression of a functional protein in Escherichia coli., PMID:2203788
For research use only. Not for human or drug use.
