Catalog No.
RHD28002
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
TFIIH basal transcription factor complex 80 kDa subunit, DNA repair protein complementing XP-D cells, General transcription and DNA repair factor IIH helicase subunit XPD, XPD, ERCC2, TFIIH p80, CXPD, BTF2 p80, TFIIH 80 kDa subunit, DNA excision repair protein ERCC-2, TFIIH subunit XPD, XPDC, Basic transcription factor 2 80 kDa subunit, Xeroderma pigmentosum group D-complementing protein
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P18074
Applications
IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1Q77
Assessing expression patterns of PTGR1, a potential biomarker for acylfulven sensitivity in urothelial carcinoma., PMID:39523403
Impaired B-cell function in ERCC2 deficiency., PMID:39055713
Gemcitabine and cisplatin plus nivolumab as organ-sparing treatment for muscle-invasive bladder cancer: a phase 2 trial., PMID:37783966
Longitudinal change of genetic variations in cetuximab-treated metastatic colorectal cancer., PMID:34315006
Deacetylase Plus Bromodomain Inhibition Downregulates ERCC2 and Suppresses the Growth of Metastatic Colon Cancer Cells., PMID:33809839
Effect of Eribulin With or Without Pembrolizumab on Progression-Free Survival for Patients With Hormone Receptor-Positive, ERBB2-Negative Metastatic Breast Cancer: A Randomized Clinical Trial., PMID:32880602
A phase II clinical study of mFOLFOX6 plus bevacizumab as first-line therapy for Japanese advanced/recurrent colorectal cancer patients., PMID:23999770
DNA repair enzyme polymorphisms and oxidative stress in a Turkish population with gastric carcinoma., PMID:21390502
DNA repair polymorphisms and the risk of stomach adenocarcinoma and severe chronic gastritis in the EPIC-EURGAST study., PMID:18641418
Influence of XPB helicase on recruitment and redistribution of nucleotide excision repair proteins at sites of UV-induced DNA damage., PMID:17509950
Evaluation of 4-aminobiphenyl-DNA adducts in human breast cancer: the influence of tobacco smoke., PMID:12727801
Detection and characterization of mechanisms of action of aneugenic chemicals., PMID:12435848
CSB is a component of RNA pol I transcription., PMID:12419226
Reduced level of the repair/transcription factor TFIIH in trichothiodystrophy., PMID:12393803
Defective dendritic cell maturation in a child with nucleotide excision repair deficiency and CD4 lymphopenia., PMID:11737070
Kinesin light-chain KLC3 expression in testis is restricted to spermatids., PMID:11319135
Molecular structure of human TFIIH., PMID:11007478
Drug-induced apoptosis is delayed and reduced in XPD lymphoblastoid cell lines: possible role of TFIIH in p53-mediated apoptotic cell death., PMID:10467415
TFIIH functions in regulating transcriptional elongation by RNA polymerase II in Xenopus oocytes., PMID:8668144
The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway., PMID:8675009
The 62- and 80-kDa subunits of transcription factor IIH mediate the interaction with Epstein-Barr virus nuclear protein 2., PMID:7724549
The human DNA repair gene, ERCC2 (XPD), corrects ultraviolet hypersensitivity and ultraviolet hypermutability of a shuttle vector replicated in xeroderma pigmentosum group D cells., PMID:8033104
The ERCC2/DNA repair protein is associated with the class II BTF2/TFIIH transcription factor., PMID:8194528
For research use only. Not for human or drug use.
