Catalog No.
RHC98703
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
PG-M, Glial hyaluronate-binding protein, CSPG2, Versican core protein, Chondroitin sulfate proteoglycan core protein 2, Large fibroblast proteoglycan, GHAP, Chondroitin sulfate proteoglycan 2, VCAN
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P13611
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1N93
Localization, Proteolytic Processing, and Binding Partners of Versican Isoforms in Vascular Lesions of Pulmonary Arterial Hypertension., PMID:40219589
Development and validation of the antibody-dependent cellular phagocytosis-based signature: A prognostic risk model of gastric cancer., PMID:39556054
Interferon-responsive neutrophils and macrophages extricate SARS-CoV-2 Omicron critical patients from the nasty fate of sepsis., PMID:39206862
Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development., PMID:38750698
TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells., PMID:37461061
V3: an enigmatic isoform of the proteoglycan versican., PMID:37399500
Single-cell RNA sequencing highlights the role of PVR/PVRL2 in the immunosuppressive tumour microenvironment in hepatocellular carcinoma., PMID:37383234
CXCL10 mediates CD8+ T cells to facilitate vessel normalization and improve the efficacy of cetuximab combined with PD-1 checkpoint inhibitors in colorectal cancer., PMID:37354983
Proteomic Insight into the Role of Exosomes in Proliferative Vitreoretinopathy Development., PMID:35628842
Expression of VCAN and its receptors in canine mammary carcinomas with or without myoepithelial proliferation., PMID:34399281
A new mouse mutant with cleavage-resistant versican and isoform-specific versican mutants demonstrate that proteolysis at the Glu441-Ala442 peptide bond in the V1 isoform is essential for interdigital web regression., PMID:34195596
An anti-ADAMTS1 treatment relieved muscle dysfunction and fibrosis in dystrophic mice., PMID:34175316
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers., PMID:32795414
Targeting of stromal versican by miR-144/199 inhibits multiple myeloma by downregulating FAK/STAT3 signalling., PMID:31532704
Anti-β2 -glycoprotein I antibody with DNA binding activity enters living monocytes via cell surface DNA and induces tissue factor expression., PMID:30368780
A Serological Biomarker of Versican Degradation is Associated with Mortality Following Acute Exacerbations of Idiopathic Interstitial Pneumonia., PMID:29728109
Massive aggrecan and versican accumulation in thoracic aortic aneurysm and dissection., PMID:29515038
Three-dimensional culture system identifies a new mode of cetuximab resistance and disease-relevant genes in colorectal cancer., PMID:28320945
Influence of Radiation Exposure During Radiotherapy. Evidence for the Increase of Versican and Heparin-Binding EGF-like Growth Factor Concentrations., PMID:27386634
Versican localizes to the nucleus in proliferating mesenchymal cells., PMID:26395512
Neuronally produced versican V2 renders C-fiber nociceptors IB4 -positive., PMID:25845936
Diabetes mellitus affects activity of calcium/calmodulin-dependent protein kinase II alpha in rat trigeminal ganglia., PMID:25701274
Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling., PMID:25452390
Role for chondroitin sulfate glycosaminoglycan in NEDD9-mediated breast cancer cell growth., PMID:25445787
Determinants of versican-V1 proteoglycan processing by the metalloproteinase ADAMTS5., PMID:25122765
The multiple, complex roles of versican and its proteolytic turnover by ADAMTS proteases during embryogenesis., PMID:24444773
Glycosyltransferases and glycosaminoglycans in bleomycin and transforming growth factor-β1-induced pulmonary fibrosis., PMID:24127863
Involvement of the serine protease inhibitor, SERPINE2, and the urokinase plasminogen activator in cumulus expansion and oocyte maturation., PMID:24023701
Kidney transplants with progressing chronic diseases express high levels of acute kidney injury transcripts., PMID:23356967
Development and validation of a three-dimensional in vitro model for uterine leiomyoma and patient-matched myometrium., PMID:22425196
CD99 is a novel prognostic stromal marker in non-small cell lung cancer., PMID:22392539
[Differential and morphogenetic potential of rat dermal papilla cells]., PMID:22292285
A novel strategy for a splice-variant selective gene ablation: the example of the versican V0/V2 knockout., PMID:22252628
Hyaluronan and versican in the control of human T-lymphocyte adhesion and migration., PMID:22155153
Zonal differences in meniscus matrix turnover and cytokine response., PMID:22062355
Segmental versican expression in the trabecular meshwork and involvement in outflow facility., PMID:21596823
Comparative immunolocalization of the elastin fiber-associated proteins fibrillin-1, LTBP-2, and MAGP-1 with components of the collagenous and proteoglycan matrix of the fetal human intervertebral disc., PMID:21540769
The roles of fractalkine/CX3CR1 system in neuronal death following pilocarpine-induced status epilepticus., PMID:21481949
Neurites regrowth of cortical neurons by GSK3beta inhibition independently of Nogo receptor 1., PMID:20374426
Proteolytic cleavage of versican during limb joint development., PMID:20101710
NG2-positive glia in the human central nervous system., PMID:19785924
Transforming growth factor beta3 regulates the versican variants in the extracellular matrix-rich uterine leiomyomas., PMID:19700613
NG2 and phosphacan are present in the astroglial scar after human traumatic spinal cord injury., PMID:19604403
Versican/PG-M Assembles Hyaluronan into Extracellular Matrix and Inhibits CD44-mediated Signaling toward Premature Senescence in Embryonic Fibroblasts., PMID:19164294
Versican overexpression in cutaneous malignant melanoma., PMID:19073385
The role of versican isoforms V0/V1 in glioma migration mediated by transforming growth factor-beta2., PMID:17453002
Induction of haem oxygenase-1 causes cortical non-haem iron increase in experimental pneumococcal meningitis: evidence that concomitant ferritin up-regulation prevents iron-induced oxidative damage., PMID:17116231
Proteolytic cleavage of versican during cardiac cushion morphogenesis., PMID:16691565
Early profiles of axonal growth and astroglial response after spinal cord hemisection and implantation of Schwann cell-seeded guidance channels in adult rats., PMID:16240391
Lesion-induced differential expression and cell association of Neurocan, Brevican, Versican V1 and V2 in the mouse dorsal root entry zone., PMID:15896911
For research use only. Not for human or drug use.
