Catalog No.
RHC96501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000
Target
Interferon-induced protein 17, Interferon-inducible protein 9-27, Leu-13 antigen, Interferon-induced transmembrane protein 1, CD225, IFI17, DSPA2a, Dispanin subfamily A member 2a, IFITM1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P13164
Applications
IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1N85
IFITM1, CD10, SMA, and h-caldesmon as a helpful combination in differential diagnosis between endometrial stromal tumor and cellular leiomyoma., PMID:34556086
IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro., PMID:34321474
A four-gene signature predicts survival and anti-CTLA4 immunotherapeutic responses based on immune classification of melanoma., PMID:33753855
Interferon-induced transmembrane protein 1 and Myxovirus resistance protein 1 are induced by polyinosinic-polycytidylic acid in cultured hCMEC/D3 human cerebral microvascular endothelial cells., PMID:31520792
Deficiencies in the CD19 complex., PMID:30075290
IFITM1 targets HIV-1 latently infected cells for antibody-dependent cytolysis., PMID:28097226
Resistance of Transmitted Founder HIV-1 to IFITM-Mediated Restriction., PMID:27640936
CD21 and CD19 deficiency: Two defects in the same complex leading to different disease modalities., PMID:26325596
Interferon-Induced Transmembrane Protein-Mediated Inhibition of Host Cell Entry of Ebolaviruses., PMID:26034199
Targeting interferon response genes sensitizes aromatase inhibitor resistant breast cancer cells to estrogen-induced cell death., PMID:25588716
A membrane topology model for human interferon inducible transmembrane protein 1., PMID:25105503
Chimeric anti-CD14 IGG2/4 Hybrid antibodies for therapeutic intervention in pig and human models of inflammation., PMID:24062486
CD19: a biomarker for B cell development, lymphoma diagnosis and therapy., PMID:23210908
Activation of CD147 with cyclophilin a induces the expression of IFITM1 through ERK and PI3K in THP-1 cells., PMID:20847954
Wnt signaling may be activated in a subset of Peutz-Jeghers syndrome polyps closely correlating to LKB1 expression., PMID:20428811
CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency., PMID:20237408
Binding of IFITM1 enhances the inhibiting effect of caveolin-1 on ERK activation., PMID:19499152
[Detection of interferon-induced transmembrane-1 gene expression for clinical diagnosis of colorectal cancer]., PMID:19033100
Functional assay of type I interferon in systemic lupus erythematosus plasma and association with anti-RNA binding protein autoantibodies., PMID:16736505
An antibody-deficiency syndrome due to mutations in the CD19 gene., PMID:16672701
The dual function of the splenic marginal zone: essential for initiation of anti-TI-2 responses but also vital in the general first-line defense against blood-borne antigens., PMID:12296846
Regulation of B lymphocyte development and activation by the CD19/CD21/CD81/Leu 13 complex requires the cytoplasmic domain of CD19., PMID:9317126
Expression cloning of an interferon-inducible 17-kDa membrane protein implicated in the control of cell growth., PMID:7559564
Expression of the neuroglandular antigen and analogues in melanoma. CD9 expression appears inversely related to metastatic potential of melanoma., PMID:8478146
IFN-alpha induces homotypic adhesion and Leu-13 expression in human B lymphoid cells., PMID:8423337
Characterization of an Epstein-Barr virus receptor on human epithelial cells., PMID:1383386
The CD19/CD21 signal transducing complex of human B lymphocytes includes the target of antiproliferative antibody-1 and Leu-13 molecules., PMID:1383329
Differential modulation of the CD-2 and CD-3 T cell activation pathways by a monoclonal antibody to Leu-13., PMID:1671002
Monoclonal antibody to the interferon-inducible protein Leu-13 triggers aggregation and inhibits proliferation of leukemic B cells., PMID:2265250
TAPA-1, the target of an antiproliferative antibody, is associated on the cell surface with the Leu-13 antigen., PMID:2398277
IFN-gamma and IFN-alpha induce the expression and synthesis of Leu 13 antigen by cultured human endothelial cells., PMID:2512344
A monoclonal antibody that induces T cell aggregation reacts with vascular endothelial cells and placental trophoblasts., PMID:2424985
For research use only. Not for human or drug use.
