Anti-UNG Antibody (R1N83)

Catalog No.

RHC96201

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000

Target

DGU, Uracil-DNA glycosylase, UNG15, UDG, UNG, UNG1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P13051

Applications

FCM, IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1N83

β-glucan induced trained immunity enhances antibody levels in a vaccination model in mice., PMID:40403021

Liver-targeted allergen immunotherapy rapidly and safely induces antigen-specific tolerance to treat allergic airway disease in mice., PMID:40238914

Orthohantavirus seoulense as a cause of acute, dengue-negative febrile illness in southern Vietnam., PMID:40219820

Improving Phenotyping of Patients With Immune-Mediated Inflammatory Diseases Through Automated Processing of Discharge Summaries: Multicenter Cohort Study., PMID:40203304

Datopotamab Deruxtecan Versus Chemotherapy in Previously Treated Inoperable/Metastatic Hormone Receptor-Positive Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer: Primary Results From TROPION-Breast01., PMID:39265124

RPA guides UNG to uracil in ssDNA to facilitate antibody class switching and repair of mutagenic uracil at the replication fork., PMID:38000394

Label-free single-cell live imaging reveals fast metabolic switch in T lymphocytes., PMID:37971737

Shear Forces Induced Platelet Clearance Is a New Mechanism of Thrombocytopenia., PMID:37883587

Vertical Transmission of SARS-CoV-2-Specific Antibodies and Cytokine Profiles in Pregnancy., PMID:37786979

Immune biomarkers associated with COVID-19 disease severity in an urban, hospitalized population., PMID:37649544

Real-World Impact of Adjuvant Anti-HER2 Treatment on Characteristics and Outcomes of Women With HER2-Positive Metastatic Breast Cancer in the ESME Program., PMID:37589218

Affinity maturation of antibody fragments: A review encompassing the development from random approaches to computational rational optimization., PMID:37423452

Isolation of Adhirons Specific for Plant Protoplast Membrane Biomarkers Is Simplified by Phagemid Design., PMID:37405641

Incidence, characteristics, management and outcome of patients with follicular lymphoma with tumor epidural compression, a study on 22 cases., PMID:37156711

Antibodies against endogenous retroviruses promote lung cancer immunotherapy., PMID:37046094

The IgH Eµ-MAR regions promote UNG-dependent error-prone repair to optimize somatic hypermutation., PMID:36865553

Mechanisms underlying the efficacy and safety of IgG, antibody fragments, and design immune biologics., PMID:36669622

Validation and Establishment of the SARS-CoV-2 Lentivirus Surrogate Neutralization Assay as a Prescreening Tool for the Plaque Reduction Neutralization Test., PMID:36602312

Association of Endocrine Therapy for HR+/ERBB2+ Metastatic Breast Cancer With Survival Outcomes., PMID:36520434

Competition for DNA binding between the genome protector replication protein A and the genome modifying APOBEC3 single-stranded DNA deaminases., PMID:36444883

Isolating and targeting a highly active, stochastic dendritic cell subpopulation for improved immune responses., PMID:36323246

Somatic hypermutation defects in two adult hyper immunoglobulin M patients., PMID:35879489

Immunoglobulin-free strategy to prevent HBV mother-to-child transmission in Cambodia (TA-PROHM): a single-arm, multicentre, phase 4 trial., PMID:35643089

HMCES protects immunoglobulin genes specifically from deletions during somatic hypermutation., PMID:35450882

Expression, purification and characterization of SARS-CoV-2 spike RBD in ExpiCHO cells., PMID:35172194

Cytoplasmic Production of Nanobodies and Nanobody-Based Reagents by Co-Expression of Sulfhydryl Oxidase and DsbC Isomerase., PMID:35157272

Tandem Substitutions in Somatic Hypermutation., PMID:35069591

Preclinical Immune Response and Safety Evaluation of the Protein Subunit Vaccine Nanocovax for COVID-19., PMID:34938290

Interference of p53:Twist1 interaction through competing nanobodies., PMID:34863830

Fam72a enforces error-prone DNA repair during antibody diversification., PMID:34819671

Simultaneous NAD(P)H and FAD fluorescence lifetime microscopy of long UVA-induced metabolic stress in reconstructed human skin., PMID:34772978

[A young woman with dyspnoea and proteinuria]., PMID:34758596

A young woman with persistent nausea, vomiting and hiccups., PMID:34641651

Priming of pancreatic cancer cells with bispecific antibody armed activated T cells sensitizes tumors for enhanced chemoresponsiveness., PMID:34123574

Nanobody-Dependent Detection of Microcystis aeruginosa by ELISA and Thermal Lens Spectrometry., PMID:33871768

An anti-HER2 nanobody binds to its antigen HER2 via two independent paratopes., PMID:33848543

The uracil-DNA glycosylase UNG protects the fitness of normal and cancer B cells expressing AID., PMID:33554121

[Recent therapeutic trends in triple-negative metastatic breast cancers: PARP inhibitors, immunotherapies and antibody-drug conjugates]., PMID:33422340

Class Switch Recombination Defects: impact on B cell maturation and antibody responses., PMID:33276124

Recombinant Proteins Co-Expressed and Co-Purified in the Presence of Antibody Fragments., PMID:33128746

Anti-tumor and immune modulating activity of T cell induced tumor-targeting effectors (TITE)., PMID:32865605

Rapid isolation of antigen-specific B-cells using droplet microfluidics., PMID:35515810

REV7 is required for processing AID initiated DNA lesions in activated B cells., PMID:32499490

A young man with convulsive laughter., PMID:32463185

Cholic Acid Stimulates MMP-9 in Human Colon Cancer Cells via Activation of MAPK, AP-1, and NF-κB Activity., PMID:32408577

Recombinant expression of nanobodies and nanobody-derived immunoreagents., PMID:32289357

A young woman with a transfusion-related pregnancy complication., PMID:31948214

Chicken MBD4 Regulates Immunoglobulin Diversification by Somatic Hypermutation., PMID:31736964

Impaired Antibody-Independent Immune Response of B Cells in Patients With Acute Dengue Infection., PMID:31736948

A compact nanobody-DNAzyme conjugate enables antigen detection and signal amplification., PMID:31682942

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