Catalog No.
RHB90801
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IP: 1:20, WB: 1:500-1:1000
Target
Proto-oncogene c-Myc, BHLHE39, MYC, Myc proto-oncogene protein, bHLHe39, Transcription factor p64, Class E basic helix-loop-helix protein 39
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P01106
Applications
IF, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1H66
Nanobody-based fluorescent immunoassay for SARS-CoV-2 spike detection via site-specific microbial transglutaminase labeling., PMID:40483875
Prognostic Value of the G2 Expression Signature and MYC Overexpression in Childhood High-Grade Osteosarcoma., PMID:40440582
B-cell lymphoma: Advances in pathogenesis, diagnosis, and targeted therapies., PMID:40435909
Engineered E. coli OMVs Carrying the Membrane-Binding hGC33 Fragment Precisely Target Liver Cancer and Effectively Treat Tumor., PMID:40433120
Deciphering the history of ERK activity from fixed-cell immunofluorescence measurements., PMID:40399273
Inhibition of Purine Metabolism Promotes the Differentiation of Neuroblastoma Driven by MYCN., PMID:40353332
Ligand-activated EGFR/MAPK signaling but not PI3K, are key resistance mechanisms to EGFR-therapy in colorectal cancer., PMID:40346041
ZMYND8 drives HER2 antibody resistance in breast cancer via lipid control of IL-27., PMID:40281007
The de novo DNA methyltransferase 3B is a novel epigenetic regulator of MYC in multiple myeloma, representing a promising therapeutic target to counter relapse., PMID:40241199
Successful treatment of primary refractory DLBCL/HGBL - MYC/BCL2 transformed from FL using glofitamab: a case report., PMID:40230856
ID3 enhances PD-L1 expression by restructuring MYC to promote colorectal cancer immune evasion., PMID:40208940
Establishment of a novel human basophil cell line for functional analysis and in vitro allergy testing., PMID:40187962
Synergistic activity of tafasitamab and metronomic chemotherapy on diffuse large B-cell lymphoma through inhibition of the AKT/mTOR signaling pathway., PMID:40175588
Zanubrutinib plus R-CHOP improves the treatment effect of newly diagnosed diffuse large B cell lymphoma with double expression of MYC and BCL-2., PMID:40145086
Blood-brain barrier crossing biopolymer targeting c-Myc and anti-PD-1 activate primary brain lymphoma immunity: Artificial intelligence analysis., PMID:40088978
Sialylated IgG-activated integrin β4-Src-Erk axis stabilizes c-Myc in a p300 lysine acetyltransferase-dependent manner to promote colorectal cancer liver metastasis., PMID:40010102
Nanoparticle-Mediated Toll-Like Receptor Activation and Dual Immune Checkpoint Downregulation for Potent Cancer Immunotherapy., PMID:40009747
A dual-mode immunosensor for detection of oncoprotein c-Myc via indirect competition using trimetallic nanocomposite as an excellent label., PMID:39984205
Single-cell analysis of neoplastic plasma cells identifies myeloma pathobiology mediators and potential targets., PMID:39855192
Subtype-specific human endogenous retrovirus K102 envelope protein is a novel serum immunosuppressive biomarker of cancer., PMID:39850893
Investigation of circulating natural autoantibodies against ANXA1 and MYC as potential biomarkers in hepatocellular carcinoma., PMID:39824386
Impacts of genomic alterations on the efficacy of HER2-targeted antibody-drug conjugates in patients with metastatic breast cancer., PMID:39806366
Targeted Next-Generation Sequencing of Cell-Free DNA to Detect MYC-Immunoglobulin Translocation and Epstein-Barr Virus DNA in Plasma of Burkitt Lymphoma Patients in East Africa., PMID:39787450
Depletion of myeloid-derived suppressor cells sensitizes murine multiple myeloma to PD-1 checkpoint inhibitors., PMID:39755583
[Clinical Features and Prognosis of Patients with Primary Extranodal Diffuse Large B-Cell Lymphoma]., PMID:39743255
Antisense oligonucleotides-based approaches for the treatment of multiple myeloma., PMID:39732226
AptaFluorescence: An aptamer-based fluorescent imaging protocol for biomolecule visualization., PMID:39729513
ITGA3 promotes pancreatic cancer progression through HIF1α- and c-Myc-driven glycolysis in a collagen I-dependent autocrine manner., PMID:39690180
Biomarker analyses from the phase III randomized CLEAR trial: lenvatinib plus pembrolizumab versus sunitinib in advanced renal cell carcinoma., PMID:39672382
Nanotechnology-Enabled Targeted Protein Degradation for Cancer Therapeutics., PMID:39663650
Extrajunctional CLDN10 cooperates with LAT1 and accelerates clear cell renal cell carcinoma progression., PMID:39639312
Prognostic Significance of C-MYC and EGFR Overexpression in Gastrointestinal Stromal Tumors: An Immunohistochemical Study., PMID:39636317
[The effect of c-Myc on regulating the immune-related ligands in Y subtype small cell lung cancer through histone deacetylase 1]., PMID:39622733
DOCK8 gene mutation alters cell subsets, BCR signaling, and cell metabolism in B cells., PMID:39616183
Impaired development of memory B cells and antibody responses in humans and mice deficient in PD-1 signaling., PMID:39603236
Delineating MYC-Mediated Escape Mechanisms from Conventional and T Cell-Redirecting Therapeutic Antibodies., PMID:39596160
Cone-rod homeobox transcriptionally activates TCF7 to promote the proliferation of retinal pigment epithelial and retinoblastoma cells in vitro., PMID:39559312
Stemness of Cancer: A Study of Triple-negative Breast Cancer From a Neuroscience Perspective., PMID:39531198
The mechanism underlying B-cell developmental dysfunction in Kawasaki disease based on single-cell transcriptomic sequencing., PMID:39507528
Isobutyric Acid Promotes Immune Evasion in Colorectal Cancer via Increased PD-L1 Expression., PMID:39503247
Engraftment of a surrogate antigen onto tumor cell surface via pHLIP peptide to universally target CAR-T cell therapy to solid tumors., PMID:39489212
NOTCH1 drives tumor plasticity and metastasis in hepatocellular carcinoma., PMID:39484457
High Prevalence of MYD88 and CD79B Mutations in Primary Sinonasal Diffuse Large B-Cell Lymphoma : Identification of an MCD-like Subtype., PMID:39483112
Caerin 1.1 and 1.9 peptides halt B16 melanoma metastatic tumours via expanding cDC1 and reprogramming tumour macrophages., PMID:39468595
Overcoming Irinotecan Resistance by Targeting Its Downstream Signaling Pathways in Colon Cancer., PMID:39456585
Clinicopathological analysis of primary central nervous system lymphoma in patients with or without HIV infection., PMID:39418717
DNp73 enhances tumor progression and immune evasion in multiple myeloma by targeting the MYC and MYCN pathways., PMID:39380995
Double hit lymphoma: contemporary understanding and practices., PMID:39378204
A peptide encoded by upstream open reading frame of MYC binds to tropomyosin receptor kinase B and promotes glioblastoma growth in mice., PMID:39356747
The ROCK-1/2 inhibitor RKI-1447 blocks N-MYC, promotes cell death, and emerges as a synergistic partner for BET inhibitors in neuroblastoma., PMID:39307412
For research use only. Not for human or drug use.
