Catalog No.
YHC23401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ser358
Predicted molecular weight
43.10 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P07197
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NF-M, NFM, Neurofilament triplet M protein, NEFM, 160 kDa neurofilament protein, NEF3, Neurofilament 3, Neurofilament medium polypeptide
Novel miRNAs, miR-937-3p, miR-4536-3p, and miR-4650-5p, can Modulate Neuronal Differentiation via the Wnt/MAPK Pathway in SH-SY5Y Cells., PMID:40316877
Quantitative proteomic analysis of the brain reveals the potential antidepressant mechanism of Jiawei Danzhi Xiaoyao San in a chronic unpredictable mild stress mouse model of depression., PMID:39957155
Biomarker discovery in progressive supranuclear palsy from human cerebrospinal fluid., PMID:39342078
Hypothalamic protein profiling from mice subjected to social defeat stress., PMID:38802853
Proteomic studies in VWA1-related neuromyopathy allowed new pathophysiological insights and the definition of blood biomarkers., PMID:38652110
Exploring Shared Genetic Signatures of Alzheimer's Disease and Multiple Sclerosis: A Bioinformatic Analysis Study., PMID:37848007
BML-281 promotes neuronal differentiation by modulating Wnt/Ca2+ and Wnt/PCP signaling pathway., PMID:37768498
Multi-omics reveals aspirin eugenol ester alleviates neurological disease., PMID:37572635
KDM6B Negatively Regulates the Neurogenesis Potential of Apical Papilla Stem Cells via HES1., PMID:37445785
Regulatory Role of Insulin on Endogenous L1 ORF1 and NEFM Gene Expression through PI3K Signaling Pathway Specifically in Neuroblastoma Cell Line., PMID:37124903
Muscle and Muscle-like Autoantigen Expression in Myasthenia Gravis Thymus: Possible Molecular Hint for Autosensitization., PMID:36979710
Novel diagnostic biomarkers related to immune infiltration in Parkinson's disease by bioinformatics analysis., PMID:36777638
SFRP4+IGFBP5hi NKT cells induced neural-like cell differentiation to contribute to adenomyosis pain., PMID:36532077
Neurotrophic Activity and Its Modulation by Zinc Ion of a Dimeric Peptide Mimicking the Brain-Derived Neurotrophic Factor N-Terminal Region., PMID:36346920
Identification of key candidate genes and biological pathways in neuropathic pain., PMID:36166989
Autophagy is a novel pathway for neurofilament protein degradation in vivo., PMID:36131358
LncRNA-ANAPC2 and lncRNA-NEFM positively regulates the inflammatory response via the miR-451/npr2/ hdac8 axis in grass carp., PMID:35843524
Valproic acid promotes differentiation of adipose tissue-derived stem cells to neuronal cells selectively expressing functional N-type voltage-gated Ca2+ channels., PMID:34891042
A panel of CSF proteins separates genetic frontotemporal dementia from presymptomatic mutation carriers: a GENFI study., PMID:34838088
Comparison of the Confluence-Initiated Neurogenic Differentiation Tendency of Adipose-Derived and Bone Marrow-Derived Mesenchymal Stem Cells., PMID:34829732
Sequencing of neurofilament genes identified NEFH Ser787Arg as a novel risk variant of sporadic amyotrophic lateral sclerosis in Chinese subjects., PMID:34511133
Multi-cohort profiling reveals elevated CSF levels of brain-enriched proteins in Alzheimer's disease., PMID:34129723
NEFM DNA methylation correlates with immune infiltration and survival in breast cancer., PMID:34001208
Dysregulated healing responses in diabetic wounds occur in the early stages postinjury., PMID:33350981
Bottom up proteomics identifies neuronal differentiation pathway networks activated by cathepsin inhibition treatment in neuroblastoma cells that are enhanced by concurrent 13-cis retinoic acid treatment., PMID:33278663
Differential DNA Methylation of the Genes for Amyloid Precursor Protein, Tau, and Neurofilaments in Human Traumatic Brain Injury., PMID:33191850
Valproic acid up-regulates the whole NO-citrulline cycle for potent iNOS-NO signaling to promote neuronal differentiation of adipose tissue-derived stem cells., PMID:33129925
Gaussian Embedding for Large-scale Gene Set Analysis., PMID:32968711
LINC00294 negatively modulates cell proliferation in glioma through a neurofilament medium-mediated pathway via interacting with miR-1278., PMID:32450002
Distribution, quantity and gene expression of mechanoreceptors in ligaments and tendons of knee joint in rabbits., PMID:32356233
The conserved DNMT1-dependent methylation regions in human cells are vulnerable to neurotoxicant rotenone exposure., PMID:32178731
Different CSF protein profiles in amyotrophic lateral sclerosis and frontotemporal dementia with C9orf72 hexanucleotide repeat expansion., PMID:32132225
All-trans-retinoid acid induces the differentiation of P19 cells into neurons involved in the PI3K/Akt/GSK3β signaling pathway., PMID:31961017
The plasma peptides of breast versus ovarian cancer., PMID:31889940
Proteomics in cerebrospinal fluid and spinal cord suggests UCHL1, MAP2 and GPNMB as biomarkers and underpins importance of transcriptional pathways in amyotrophic lateral sclerosis., PMID:31701227
Valproic acid promotes mature neuronal differentiation of adipose tissue-derived stem cells through iNOS-NO-sGC signaling pathway., PMID:31484045
Bottom up proteomics reveals novel differentiation proteins in neuroblastoma cells treated with 13-cis retinoic acid., PMID:31472280
Tanycytic TSPO inhibition induces lipophagy to regulate lipid metabolism and improve energy balance., PMID:31469345
Changes in mechanoreceptors in rabbits' anterior cruciate ligaments with age., PMID:30927131
The plasma peptides of ovarian cancer., PMID:30598658
Differential Proteome Analysis of Human Neuroblastoma Xenograft Primary Tumors and Matched Spontaneous Distant Metastases., PMID:30228356
Dysregulation of human NEFM and NEFH mRNA stability by ALS-linked miRNAs., PMID:30029677
Identification of Electrophysiological Changes in Alzheimer's Disease: A Microarray Based Transcriptomics and Molecular Pathway Analysis Study., PMID:29065845
Ulk4 deficiency leads to hypomyelination in mice., PMID:29034508
The Networks of Genes Encoding Palmitoylated Proteins in Axonal and Synaptic Compartments Are Affected in PPT1 Overexpressing Neuronal-Like Cells., PMID:28878621
The Alzheimer's disease transcriptome mimics the neuroprotective signature of IGF-1 receptor-deficient neurons., PMID:28595357
NEFM (Neurofilament Medium) Polypeptide, a Marker for Zona Glomerulosa Cells in Human Adrenal, Inhibits D1R (Dopamine D1 Receptor)-Mediated Secretion of Aldosterone., PMID:28584012
Transcriptome Pathway Analysis of Pathological and Physiological Aldosterone-Producing Human Tissues., PMID:27777363
Proliferation and Survival of Embryonic Sympathetic Neuroblasts by MYCN and Activated ALK Signaling., PMID:27707976
Sub-Chronic Neuropathological and Biochemical Changes in Mouse Visual System after Repetitive Mild Traumatic Brain Injury., PMID:27088355
For research use only. Not for human or drug use.
