Catalog No.
RHA05601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
PCTA-1, Po66 carbohydrate-binding protein, Po66-CBP, Galectin-8, Gal-8, LGALS8, Prostate carcinoma tumor antigen 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O00214
Applications
FCM, IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1C69
Galectin-8 and GEL01 as potential adjuvants to enhance the immune response induced by a DNA vaccine against bovine alphaherpesvirus Type-1., PMID:39854916
Expression of Intracellular Galectin-8 and -9 in Endometrial Cancer., PMID:39000016
Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors., PMID:38232701
BST2, a Novel Inhibitory Receptor, Is Involved in NK Cell Cytotoxicity through Its Cytoplasmic Tail Domain., PMID:36232695
A Neoglycoprotein-Immobilized Fluorescent Magnetic Bead Suspension Multiplex Array for Galectin-Binding Studies., PMID:34684775
GALECTIN-8 Is a Neuroprotective Factor in the Brain that Can Be Neutralized by Human Autoantibodies., PMID:31119556
Serum biomarker panels for the diagnosis of gastric cancer., PMID:30873760
Galectin-8 induces endothelial hyperpermeability through the eNOS pathway involving S-nitrosylation-mediated adherens junction disassembly., PMID:30624618
Kojic acid inhibits senescence of human corneal endothelial cells via NF-κB and p21 signaling pathways., PMID:30597146
Galectin-8 Favors the Presentation of Surface-Tethered Antigens by Stabilizing the B Cell Immune Synapse., PMID:30540943
Interleukin-6 signalling mediates Galectin-8 co-stimulatory activity of antigen-specific CD4 T-cell response., PMID:29972692
Galectin-8 as an immunosuppressor in experimental autoimmune encephalomyelitis and a target of human early prognostic antibodies in multiple sclerosis., PMID:28650992
Multi-layered control of Galectin-8 mediated autophagy during adenovirus cell entry through a conserved PPxY motif in the viral capsid., PMID:28192531
Comparison of galectin expression signatures in rejected and accepted murine corneal allografts., PMID:25961492
Humoral Immune Response against Nontargeted Tumor Antigens after Treatment with Sipuleucel-T and Its Association with Improved Clinical Outcome., PMID:25649018
Examination of the role of galectins in plasma cell differentiation., PMID:25253139
Galectin-8 binds to LFA-1, blocks its interaction with ICAM-1 and is counteracted by anti-Gal-8 autoantibodies isolated from lupus patients., PMID:24346075
Galectin-8 promotes cytoskeletal rearrangement in trabecular meshwork cells through activation of Rho signaling., PMID:22973445
Autoantibodies against galectins are associated with antiphospholipid syndrome in patients with systemic lupus erythematosus., PMID:22887862
Non-synonymous single nucleotide polymorphisms in genes for immunoregulatory galectins: association of galectin-8 (F19Y) occurrence with autoimmune diseases in a Caucasian population., PMID:22683700
Novel role for galectin-8 protein as mediator of coagulation factor V endocytosis by megakaryocytes., PMID:22267735
Galectin-1 is part of human trophoblast invasion machinery--a functional study in vitro., PMID:22174828
Galectin-8 in IgA nephritis: decreased binding of IgA by galectin-8 affinity chromatography and associated increased binding in non-IgA serum glycoproteins., PMID:22173878
Galectin-1 and galectin-8 have redundant roles in promoting plasma cell formation., PMID:21753146
Quantitative immunohistochemical fingerprinting of adhesion/growth-regulatory galectins in salivary gland tumours: divergent profiles with diagnostic potential., PMID:21410745
Antibody responses to galectin-8, TARP and TRAP1 in prostate cancer patients treated with a GM-CSF-secreting cellular immunotherapy., PMID:20499060
Innate immune lectins kill bacteria expressing blood group antigen., PMID:20154696
Autoantibodies against galectin-8: their specificity, association with lymphopenia in systemic lupus erythematosus and detection in rheumatoid arthritis and acute inflammation., PMID:19395456
Unique chicken tandem-repeat-type galectin: implications of alternative splicing and a distinct expression profile compared to those of the three proto-type proteins., PMID:19344160
Galectin-8 induces apoptosis in Jurkat T cells by phosphatidic acid-mediated ERK1/2 activation supported by protein kinase A down-regulation., PMID:19276072
Induction of cell adhesion by galectin-8 and its target molecules in Jurkat T-cells., PMID:18024965
The tumor antigen repertoire identified in tumor-bearing neu transgenic mice predicts human tumor antigens., PMID:17018635
[Antibodies against galectin-8 in patients with systemic lupus erythematosus]., PMID:16554922
Galectin-8 binds specific beta1 integrins and induces polarized spreading highlighted by asymmetric lamellipodia in Jurkat T cells., PMID:16368432
Toward functional glycomics by localization of tissue lectins: immunohistochemical galectin fingerprinting during diethylstilbestrol-induced kidney tumorigenesis in male Syrian hamster., PMID:15609042
Galectin fingerprinting by immuno- and lectin histochemistry in cutaneous lymphoma., PMID:11862481
Galectin-8 expression decreases in cancer compared with normal and dysplastic human colon tissue and acts significantly on human colon cancer cell migration as a suppressor., PMID:11839721
Immunohistochemical expression of the intracellular component of galectin-8 in squamous cell metaplasia of the bronchial epithelium in neoplastic and benign processes., PMID:11795826
Expression of Po66-CBP, a galectin-8, in different types of primary and secondary broncho-pulmonary tumors., PMID:11748478
Two messenger RNAs and five isoforms for Po66-CBP, a galectin-8 homolog in a human lung carcinoma cell line., PMID:11675018
Detection of macrophage migration inhibitory factor (MIF) in human cholesteatomas and functional implications of correlations to recurrence status and to expression of matrix metalloproteinases-3/9, retinoic acid receptor-beta, and anti-apoptotic galectin-3., PMID:11568623
Immunohistochemical profile of galectin-8 expression in benign and malignant tumors of epithelial, mesenchymatous and adipous origins, and of the nervous system., PMID:11510978
The levels of expression of galectin-3, but not of galectin-1 and galectin-8, correlate with apoptosis in human cholesteatomas., PMID:11404618
Galectin-8 functions as a matricellular modulator of cell adhesion., PMID:11371555
Expression of Po66-CBP, a type-8 galectin, in different healthy, tumoral and peritumoral tissues., PMID:10697573
Surface-epitope masking and expression cloning identifies the human prostate carcinoma tumor antigen gene PCTA-1 a member of the galectin gene family., PMID:8692978
Galectin-8. A new rat lectin, related to galectin-4., PMID:7852431
For research use only. Not for human or drug use.
