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Anti-GATA2/3 Antibody (R1C23)

Catalog #:   RHD60401 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IF, IHC, IP, WB
Accession: P23769, P23771
Overview

Catalog No.

RHD60401

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000

Target

DCML, GATA binding protein 2, GATA binding protein 3, HDR, HDRS, IMD21, MONOMAC, NFE1B, GATA2/3

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P23769, P23771

Applications

IF, IHC, IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at +4 ℃ short term (1-2 weeks). Store at -20 ℃ 12 months. Store at -80 ℃ long term.

Clone ID

R1C23

Data Image
  • Immunofluorescence
    Immunofluorescent analysis of K562 cells, using GATA2/3 Antibody .
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded mouse kidney, using GATA2/3 Antibody.
  • Western blot
    All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
  • Western blot
    All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
  • Western blot
    All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
  • Western blot
    All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
References

The progression of multiple myeloma is regulated by LILRB1 via the GATA2-SAGE1 pathway., PMID:40415416

Drug survival of omalizumab in atopic asthma: Impact of clinical and genetic variables., PMID:40189906

IL-6/GATA2/SERPINE1 pathway is implicated in regulating cellular senescence after acute kidney injury., PMID:40007559

Immunohistochemical Analysis of GATA2 Expression in Endometrium and its Relationship with Hormone Receptor Expression in Benign and Premalignant Endometrial Disorders., PMID:39443360

SingleNucleotide Polymorphisms as Biomarkers of Mepolizumab and Benralizumab Treatment Response in Severe Eosinophilic Asthma., PMID:39125709

Linking GATA2 to myeloid dysplasia and complex cytogenetics in adult myelodysplastic neoplasm and acute myeloid leukemia., PMID:38029365

Identification of MARK2, CCDC71, GATA2, and KLRC3 as candidate diagnostic genes and potential therapeutic targets for repeated implantation failure with antiphospholipid syndrome by integrated bioinformatics analysis and machine learning., PMID:37901230

Influence of Genetics on the Response to Omalizumab in Patients with Severe Uncontrolled Asthma with an Allergic Phenotype., PMID:37108192

Inhibition of CXCR1/2 reduces the emperipolesis between neutrophils and megakaryocytes in the Gata1low model of myelofibrosis., PMID:36863479

Inflammatory diseases in hematology: a review., PMID:35938681

Molecular Classification and Overcoming Therapy Resistance for Acute Myeloid Leukemia with Adverse Genetic Factors., PMID:35682627

A CGA/EGFR/GATA2 positive feedback circuit confers chemoresistance in gastric cancer., PMID:35289315

Panaxdiol saponins component promotes hematopoiesis by regulating GATA transcription factors of intracellular signaling pathway in mouse bone marrow., PMID:35282082

Clonal architecture predicts clinical outcomes and drug sensitivity in acute myeloid leukemia., PMID:34903734

Combined Mutation of the GATA2 Gene and STAT5B Gene in a Patient with Hypogammaglobulinemia and Autoimmunity., PMID:34670919

The high affinity IgE receptor: a signaling update., PMID:33838574

G ATA2 mediates the negative regulation of the prepro-thyrotropin-releasing hormone gene by liganded T3 receptor β2 in the rat hypothalamic paraventricular nucleus., PMID:33201916

Anti-S100A4 Antibody Therapy Is Efficient in Treating Aggressive Prostate Cancer and Reversing Immunosuppression: Serum and Biopsy S100A4 as a Clinical Predictor., PMID:32999046

Familial Emberger Syndrome With Autoimmunity, Hyper-Immunoglobulin E and Lymphatic Impairment Caused by a Novel GATA2 Mutation., PMID:32497548

GATA2 and Progesterone Receptor Interaction in Endometrial Stromal Cells Undergoing Decidualization., PMID:32335672

GATA2 mutation underlies hemophagocytic lymphohistiocytosis in an adult with primary cytomegalovirus infection., PMID:31350183

GATA-2-deficient mast cells limit IgE-mediated immediate hypersensitivity reactions in human subjects., PMID:31102699

Persistent stimulation with Mycobacterium tuberculosis antigen impairs the proliferation and transcriptional program of hematopoietic cells in bone marrow., PMID:31082645

Characterisation of Osteopontin in an In Vitro Model of Embryo Implantation., PMID:31075896

Blockade of TNFα to Improve Human CD34+ Cell Repopulating Activity in Allogeneic Stem Cell Transplantation., PMID:30723481

Life-Threatening Primary Varicella Zoster Virus Infection With Hemophagocytic Lymphohistiocytosis-Like Disease in GATA2 Haploinsufficiency Accompanied by Expansion of Double Negative T-Lymphocytes., PMID:30564229

GATA3 immunoreactivity expands the transcription factor profile of pituitary neuroendocrine tumors., PMID:30390035

The effect of gap junction-mediated transfer of miR-200b on osteogenesis and angiogenesis in a co-culture of MSCs and HUVECs., PMID:29898921

Cells with hematopoietic potential reside within mouse proepicardium., PMID:29549430

Establishment of a Screening System to Identify Novel GATA-2 Transcriptional Regulators., PMID:29343653

The transcription factors GATA2 and microphthalmia-associated transcription factor regulate Hdc gene expression in mast cells and are required for IgE/mast cell-mediated anaphylaxis., PMID:29277702

In vivo single cell analysis reveals Gata2 dynamics in cells transitioning to hematopoietic fate., PMID:29217535

Successful Nonmyeloablative Allogeneic Stem Cell Transplant in a Child With Emberger Syndrome and GATA2 Mutation., PMID:29189513

Allogeneic Hematopoietic Cell Transplantation Using Treosulfan-Based Conditioning for Treatment of Marrow Failure Disorders., PMID:28602958

Tissue organization alters gene expression in equine induced trophectoderm cells., PMID:28161437

Subacute demyelinating polyradiculoneuropathy complicating Epstein-Barr virus infection in GATA2 haploinsufficiency., PMID:28093780

Human induced pluripotent stem cells derived endothelial cells mimicking vascular inflammatory response under flow., PMID:26858818

The Transcription Factor Ehf Is Involved in TGF-β-Induced Suppression of FcεRI and c-Kit Expression and FcεRI-Mediated Activation in Mast Cells., PMID:26297757

GATA2 deficiency in children and adults with severe pulmonary alveolar proteinosis and hematologic disorders., PMID:26264606

Fibroblast-Negative CD34-Negative Cells from Human Adipose Tissue Contain Mesodermal Precursors for Endothelial and Mesenchymal Cells., PMID:26068131

Characterization of surface phenotypic molecules of teleost dendritic cells., PMID:25445909

Transcription factors involved in prostate gland adaptation to androgen deprivation., PMID:24886974

Presence of hypogammaglobulinemia and abnormal antibody responses in GATA2 deficiency., PMID:24726394

The epigenetic modifiers 5-aza-2'-deoxycytidine and trichostatin A influence adipocyte differentiation in human mesenchymal stem cells., PMID:23797495

Efficient commitment to functional CD34+ progenitor cells from human bone marrow mesenchymal stem-cell-derived induced pluripotent stem cells., PMID:22496789

GATA transcription factors are involved in IgE-dependent mast cell degranulation by enhancing the expression of phospholipase C-γ1., PMID:22390417

The clinical and environmental determinants of airway transcriptional profiles in allergic asthma., PMID:22246175

Adenosine promotes GATA-2-regulated p53 gene transcription to induce HepG2 cell apoptosis., PMID:22178888

Notch-induced hIL-6 production facilitates the maintenance of self-renewal of hCD34+ cord blood cells through the activation of Jak-PI3K-STAT3 pathway., PMID:22062221

Biphasic and dosage-dependent regulation of osteoclastogenesis by β-catenin., PMID:21876000

Datasheet
$ 290
Product specifications
50 μg 290 100 μg 484

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Anti-GATA2/3 Antibody (R1C23) [RHD60401]
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