Catalog No.
RHD60401
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
DCML, GATA binding protein 2, GATA binding protein 3, HDR, HDRS, IMD21, MONOMAC, NFE1B, GATA2/3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P23769, P23771
Applications
IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4 ℃ short term (1-2 weeks).
Store at -20 ℃ 12 months.
Store at -80 ℃ long term.
Clone ID
R1C23
The progression of multiple myeloma is regulated by LILRB1 via the GATA2-SAGE1 pathway., PMID:40415416
Drug survival of omalizumab in atopic asthma: Impact of clinical and genetic variables., PMID:40189906
IL-6/GATA2/SERPINE1 pathway is implicated in regulating cellular senescence after acute kidney injury., PMID:40007559
Immunohistochemical Analysis of GATA2 Expression in Endometrium and its Relationship with Hormone Receptor Expression in Benign and Premalignant Endometrial Disorders., PMID:39443360
SingleNucleotide Polymorphisms as Biomarkers of Mepolizumab and Benralizumab Treatment Response in Severe Eosinophilic Asthma., PMID:39125709
Linking GATA2 to myeloid dysplasia and complex cytogenetics in adult myelodysplastic neoplasm and acute myeloid leukemia., PMID:38029365
Identification of MARK2, CCDC71, GATA2, and KLRC3 as candidate diagnostic genes and potential therapeutic targets for repeated implantation failure with antiphospholipid syndrome by integrated bioinformatics analysis and machine learning., PMID:37901230
Influence of Genetics on the Response to Omalizumab in Patients with Severe Uncontrolled Asthma with an Allergic Phenotype., PMID:37108192
Inhibition of CXCR1/2 reduces the emperipolesis between neutrophils and megakaryocytes in the Gata1low model of myelofibrosis., PMID:36863479
Inflammatory diseases in hematology: a review., PMID:35938681
Molecular Classification and Overcoming Therapy Resistance for Acute Myeloid Leukemia with Adverse Genetic Factors., PMID:35682627
A CGA/EGFR/GATA2 positive feedback circuit confers chemoresistance in gastric cancer., PMID:35289315
Panaxdiol saponins component promotes hematopoiesis by regulating GATA transcription factors of intracellular signaling pathway in mouse bone marrow., PMID:35282082
Clonal architecture predicts clinical outcomes and drug sensitivity in acute myeloid leukemia., PMID:34903734
Combined Mutation of the GATA2 Gene and STAT5B Gene in a Patient with Hypogammaglobulinemia and Autoimmunity., PMID:34670919
The high affinity IgE receptor: a signaling update., PMID:33838574
G ATA2 mediates the negative regulation of the prepro-thyrotropin-releasing hormone gene by liganded T3 receptor β2 in the rat hypothalamic paraventricular nucleus., PMID:33201916
Anti-S100A4 Antibody Therapy Is Efficient in Treating Aggressive Prostate Cancer and Reversing Immunosuppression: Serum and Biopsy S100A4 as a Clinical Predictor., PMID:32999046
Familial Emberger Syndrome With Autoimmunity, Hyper-Immunoglobulin E and Lymphatic Impairment Caused by a Novel GATA2 Mutation., PMID:32497548
GATA2 and Progesterone Receptor Interaction in Endometrial Stromal Cells Undergoing Decidualization., PMID:32335672
GATA2 mutation underlies hemophagocytic lymphohistiocytosis in an adult with primary cytomegalovirus infection., PMID:31350183
GATA-2-deficient mast cells limit IgE-mediated immediate hypersensitivity reactions in human subjects., PMID:31102699
Persistent stimulation with Mycobacterium tuberculosis antigen impairs the proliferation and transcriptional program of hematopoietic cells in bone marrow., PMID:31082645
Characterisation of Osteopontin in an In Vitro Model of Embryo Implantation., PMID:31075896
Blockade of TNFα to Improve Human CD34+ Cell Repopulating Activity in Allogeneic Stem Cell Transplantation., PMID:30723481
Life-Threatening Primary Varicella Zoster Virus Infection With Hemophagocytic Lymphohistiocytosis-Like Disease in GATA2 Haploinsufficiency Accompanied by Expansion of Double Negative T-Lymphocytes., PMID:30564229
GATA3 immunoreactivity expands the transcription factor profile of pituitary neuroendocrine tumors., PMID:30390035
The effect of gap junction-mediated transfer of miR-200b on osteogenesis and angiogenesis in a co-culture of MSCs and HUVECs., PMID:29898921
Cells with hematopoietic potential reside within mouse proepicardium., PMID:29549430
Establishment of a Screening System to Identify Novel GATA-2 Transcriptional Regulators., PMID:29343653
The transcription factors GATA2 and microphthalmia-associated transcription factor regulate Hdc gene expression in mast cells and are required for IgE/mast cell-mediated anaphylaxis., PMID:29277702
In vivo single cell analysis reveals Gata2 dynamics in cells transitioning to hematopoietic fate., PMID:29217535
Successful Nonmyeloablative Allogeneic Stem Cell Transplant in a Child With Emberger Syndrome and GATA2 Mutation., PMID:29189513
Allogeneic Hematopoietic Cell Transplantation Using Treosulfan-Based Conditioning for Treatment of Marrow Failure Disorders., PMID:28602958
Tissue organization alters gene expression in equine induced trophectoderm cells., PMID:28161437
Subacute demyelinating polyradiculoneuropathy complicating Epstein-Barr virus infection in GATA2 haploinsufficiency., PMID:28093780
Human induced pluripotent stem cells derived endothelial cells mimicking vascular inflammatory response under flow., PMID:26858818
The Transcription Factor Ehf Is Involved in TGF-β-Induced Suppression of FcεRI and c-Kit Expression and FcεRI-Mediated Activation in Mast Cells., PMID:26297757
GATA2 deficiency in children and adults with severe pulmonary alveolar proteinosis and hematologic disorders., PMID:26264606
Fibroblast-Negative CD34-Negative Cells from Human Adipose Tissue Contain Mesodermal Precursors for Endothelial and Mesenchymal Cells., PMID:26068131
Characterization of surface phenotypic molecules of teleost dendritic cells., PMID:25445909
Transcription factors involved in prostate gland adaptation to androgen deprivation., PMID:24886974
Presence of hypogammaglobulinemia and abnormal antibody responses in GATA2 deficiency., PMID:24726394
The epigenetic modifiers 5-aza-2'-deoxycytidine and trichostatin A influence adipocyte differentiation in human mesenchymal stem cells., PMID:23797495
Efficient commitment to functional CD34+ progenitor cells from human bone marrow mesenchymal stem-cell-derived induced pluripotent stem cells., PMID:22496789
GATA transcription factors are involved in IgE-dependent mast cell degranulation by enhancing the expression of phospholipase C-γ1., PMID:22390417
The clinical and environmental determinants of airway transcriptional profiles in allergic asthma., PMID:22246175
Adenosine promotes GATA-2-regulated p53 gene transcription to induce HepG2 cell apoptosis., PMID:22178888
Notch-induced hIL-6 production facilitates the maintenance of self-renewal of hCD34+ cord blood cells through the activation of Jak-PI3K-STAT3 pathway., PMID:22062221
Biphasic and dosage-dependent regulation of osteoclastogenesis by β-catenin., PMID:21876000