Catalog No.
RHN24404
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
ERIC-1, ERIC1, TAC3, Transforming acidic coiled-coil-containing protein 3, TACC3, TACC3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9Y6A5
Applications
IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4 ℃ short term (1-2 weeks).
Store at -20 ℃ 12 months.
Store at -80 ℃ long term.
Clone ID
R1A60
Male meiotic spindle poles are stabilized by TACC3 and cKAP5/chTOG differently from female meiotic or somatic mitotic spindles in mice., PMID:38413710
Targeting TACC3 Induces Immunogenic Cell Death and Enhances T-DM1 Response in HER2-Positive Breast Cancer., PMID:38319231
Reviving immunogenic cell death upon targeting TACC3 enhances T-DM1 response in HER2-positive breast cancer., PMID:37745348
Genomic Profiling of Circulating Tumor DNA in Relapsed EGFR-mutated Lung Adenocarcinoma Reveals an Acquired FGFR3-TACC3 Fusion., PMID:28089157
FGFR3-TACC3 fusion proteins act as naturally occurring drivers of tumor resistance by functionally substituting for EGFR/ERK signaling., PMID:27345413
FGFR inhibitors: Effects on cancer cells, tumor microenvironment and whole-body homeostasis (Review)., PMID:27245147
Detection, Characterization, and Inhibition of FGFR-TACC Fusions in IDH Wild-type Glioma., PMID:25609060
Self-assembly and sorting of acentrosomal microtubules by TACC3 facilitate kinetochore capture during the mitotic spindle assembly., PMID:24003142
Downregulation of specific miRNAs in hyperdiploid multiple myeloma mimics the oncogenic effect of IgH translocations occurring in the non-hyperdiploid subtype., PMID:23174883
A novel cell-based, high-content assay for phosphorylation of Lats2 by Aurora A., PMID:21788394
A critical role of integrin-linked kinase, ch-TOG and TACC3 in centrosome clustering in cancer cells., PMID:20838383
Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions., PMID:20479470
TOGp regulates microtubule assembly and density during mitosis and contributes to chromosome directional instability., PMID:19373773
Meiotic regulation of TPX2 protein levels governs cell cycle progression in mouse oocytes., PMID:18833336
Expression of transforming acidic coiled-coil containing protein 3 is a novel independent prognostic marker in non-small cell lung cancer., PMID:16930330
Transforming acidic coiled-coil-containing protein 4 interacts with centrosomal AKAP350 and the mitotic spindle apparatus., PMID:12015314
Characterization and localization of expression of an erythropoietin-induced gene, ERIC-1/TACC3, identified in erythroid precursor cells., PMID:11298601
For research use only. Not for human or drug use.
