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Anti-TACC3 Antibody (R1A60)

Catalog #:   RHN24404 Specific References (17) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IF, IHC, WB
Accession: Q9Y6A5
Overview

Catalog No.

RHN24404

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000

Target

ERIC-1, ERIC1, TAC3, Transforming acidic coiled-coil-containing protein 3, TACC3, TACC3

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9Y6A5

Applications

IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at +4 ℃ short term (1-2 weeks). Store at -20 ℃ 12 months. Store at -80 ℃ long term.

Clone ID

R1A60

Data Image
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human liver cancer, using TACC3 Antibody.
  • Western blot
    Western blot analysis of TACC3 expression in C6 cell lysate.
References

Male meiotic spindle poles are stabilized by TACC3 and cKAP5/chTOG differently from female meiotic or somatic mitotic spindles in mice., PMID:38413710

Targeting TACC3 Induces Immunogenic Cell Death and Enhances T-DM1 Response in HER2-Positive Breast Cancer., PMID:38319231

Reviving immunogenic cell death upon targeting TACC3 enhances T-DM1 response in HER2-positive breast cancer., PMID:37745348

Genomic Profiling of Circulating Tumor DNA in Relapsed EGFR-mutated Lung Adenocarcinoma Reveals an Acquired FGFR3-TACC3 Fusion., PMID:28089157

FGFR3-TACC3 fusion proteins act as naturally occurring drivers of tumor resistance by functionally substituting for EGFR/ERK signaling., PMID:27345413

FGFR inhibitors: Effects on cancer cells, tumor microenvironment and whole-body homeostasis (Review)., PMID:27245147

Detection, Characterization, and Inhibition of FGFR-TACC Fusions in IDH Wild-type Glioma., PMID:25609060

Self-assembly and sorting of acentrosomal microtubules by TACC3 facilitate kinetochore capture during the mitotic spindle assembly., PMID:24003142

Downregulation of specific miRNAs in hyperdiploid multiple myeloma mimics the oncogenic effect of IgH translocations occurring in the non-hyperdiploid subtype., PMID:23174883

A novel cell-based, high-content assay for phosphorylation of Lats2 by Aurora A., PMID:21788394

A critical role of integrin-linked kinase, ch-TOG and TACC3 in centrosome clustering in cancer cells., PMID:20838383

Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions., PMID:20479470

TOGp regulates microtubule assembly and density during mitosis and contributes to chromosome directional instability., PMID:19373773

Meiotic regulation of TPX2 protein levels governs cell cycle progression in mouse oocytes., PMID:18833336

Expression of transforming acidic coiled-coil containing protein 3 is a novel independent prognostic marker in non-small cell lung cancer., PMID:16930330

Transforming acidic coiled-coil-containing protein 4 interacts with centrosomal AKAP350 and the mitotic spindle apparatus., PMID:12015314

Characterization and localization of expression of an erythropoietin-induced gene, ERIC-1/TACC3, identified in erythroid precursor cells., PMID:11298601

Datasheet

Document Download

Anti-TACC3 Antibody (R1A60).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-TACC3 Antibody (R1A60) [RHN24404]
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