Catalog No.
AHF18601
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Ser19-Lys352
Predicted molecular weight
58.5kDa
Nature
Recombinant
Endotoxin level
< 0.01 EU/µg as determined by LAL test.
Purity
>90% as determined by SDS-PAGE.
Accession
P56704
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
25mM Tris-HCl, 500mM NaCl, pH 8.2, 5% Trehalose, 2% Mannitol.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at ≤-80°C, stable for 1 year after receipt. Store at ≤-80°C, stable for 3 months under sterile conditions after opening.
Alternative Names
Protein Wnt-3a, WNT3A
Efficient Generation of Induced Pluripotent Stem Cell-Derived Definitive Endoderm Cells with Growth Factors and Small Molecules., PMID:40497991
Quantification of Wnt3a, Wnt5a and Wnt16 Binding to Multiple Frizzleds Under Physiological Conditions Using NanoBit/BRET., PMID:40497984
Activation of the Wnt signaling pathway and its role in epithelial-mesenchymal transition and hepatic fibrosis in alveolar echinococcosis., PMID:40496021
The mechanism of promoting angiogenesis after cerebral infarction by scalp acupuncture based on MATN2/WNT3a/β-catenin., PMID:40471365
Investigation of differentiation conditions for canine duodenum, upper jejunum, and ileum crypt-derived cells for drug transport and metabolism., PMID:40450898
Effect of HDAC4 regulation of β-catenin signaling pathway on cardiac injury in spontaneously hypertensive rats and its mechanism., PMID:40439605
Optimizing Wnt activation in fetal calf serum (FCS)-free organoid expansion media., PMID:40438536
Lipid droplet accumulation impairs osseointegration by disturbing the osteogenesis-osteoclasis balance on titanium implant surface in hyperlipidemia., PMID:40437476
Engineered E. coli OMVs Carrying the Membrane-Binding hGC33 Fragment Precisely Target Liver Cancer and Effectively Treat Tumor., PMID:40433120
Exploring the Bone-Liver Axis: Impact of Acute Ethanol Intoxication on Post-Traumatic Liver Inflammation and Damage Following Femur Fracture., PMID:40430063
WNT-induced association of Frizzled and LRP6 is not sufficient for the initiation of WNT/β-catenin signaling., PMID:40413190
Matrine Inhibits the Wnt3a/β-Catenin Signalling to Attenuate Pressure Overload-Induced Atrial Remodelling and Vulnerability to Atrial Fibrillation., PMID:40407710
Porcupine inhibition enhances hypertrophic cartilage differentiation., PMID:40406350
Piezo1 Is an Early Mediator During Topography-Stimulated Osteogenic Differentiation of Bone Mesenchymal Stem Cells., PMID:40405805
Generation and functional characterization of tuft cells in non-human primate pancreatic ducts through organoid culture systems., PMID:40395933
Safranal-loaded gold nanoparticles alleviate hepatocellular carcinoma via targeting the Wnt/β-catenin pathway., PMID:40389761
Histone Deacetylase 6 Controls Atrial Fibrosis and Remodeling in Postinfarction Mice Through the Modulation of Wnt3a/GSK-3β Signaling., PMID:40377174
Plastrum Testudinis Stimulates Bone Formation through Wnt/β-catenin Signaling Pathway Regulated by miR-214., PMID:40358879
Ishophloroglucin A Isolated From Ishige okamurae Stimulates Osteoblast Differentiation Through Activation of the Bone Morphogenetic Protein and Wnt/β-Catenin Signaling Pathways in MC3T3-E1 Cells., PMID:40343669
Venetoclax confers synthetic lethality to chidamide in preclinical models with transformed follicular lymphoma., PMID:40320542
CLCa mediates a novel cross-talk between Wnt secretion and actin organization., PMID:40316417
Ref-1 redox activity modulates canonical Wnt signaling in endothelial cells., PMID:40305885
Improvement of spatial memory dysfunction in type 2 diabetic mice through a low-carbohydrate and high-protein diet: Potential role of LRP6/Wnt3a signaling in the hippocampus., PMID:40288500
KIF26B promotes bladder cancer progression via activating Wnt/β-catenin signaling in a TRAF2-dependent pathway., PMID:40253697
Involvement of miRNA-204 carried by the exosomes of macrophages in the AT2 receptor-mediated improvement of vascular calcification., PMID:40249512
METTL14-mediated m6A RNA methylation promotes the osteogenic differentiation of pPDLSCs by regulating WNT3A., PMID:40249476
14,15-EET Maintains Mitochondrial Homeostasis to Inhibit Neuronal Pyroptosis After Ischemic Stroke., PMID:40235438
Naringin promotes osteoblast differentiation and ameliorates osteoporosis in ovariectomized mice., PMID:40221578
METTL3-mediated m6A modification of MT1G inhibits papillary thyroid carcinoma cell growth and metastasis via Wnt/β-catenin pathway., PMID:40198928
The dual role of titanium particles in osteolysis: implications for gene therapy in prosthesis loosening., PMID:40156068
Wnt3a is an early regulator of the Wolffian duct directionality via the regulation of apicobasal cell polarity., PMID:40154784
Transcription Factor FOSL1 Promotes Cisplatin Resistance in Non-Small Cell Lung Cancer Cells by Modulating the Wnt3a/β-Catenin Signaling through Upregulation of PLIN3 Expression., PMID:40152390
Anaplastic lymphoma kinase enhances Wnt signaling through R-spondin: A new dimension to ALK-mediated oncogenesis., PMID:40132715
The miR-34a-5p Promotes Hippocampal Neuronal Ferroptosis in Epilepsy by Regulating SIRT1., PMID:40126751
Molecular structure of Fgfbp1 protein and its regulation of zebrafish cartilage development and homeostasis: Implications for Wnt signaling and ECM stability., PMID:40120897
Highly expressed GCN1 is associated with cancer progression and poor prognosis in hepatocellular carcinoma patients., PMID:40114124
Circular RNA circHSPA8 Aggravates Metastasis by Acting as a Competitive Inhibitor of miR-195-5p to Upregulate WNT3A Expression in Breast Cancer., PMID:40099939
Proteomic analysis and effects on osteogenic differentiation of exosomes from patients with ossification of the spinal ligament., PMID:40098982
YBX1-driven TUBB6 upregulation facilitates ocular angiogenesis via WNT3A-FZD8 pathway., PMID:40083923
Transcriptome analysis of testis and epididymis identifies key genes and pathways regulating gander sperm motility., PMID:40081175
Construction of Large-Scale Bioengineered Hair Germs and In Vivo Transplantation., PMID:40042061
Taohong Siwu Decoction Combined With the LncRNA H19/miR-675-5p Axis Repairs Limb Ischemia-Reperfusion Injury Through the Regulation of the Wnt3a/Ca2+ Signaling Pathway., PMID:40034562
Elaidic acid induces testicular oxidative stress, inflammation, Wnt/β-catenin disruption and abnormalities in steroidogenesis, spermatogenesis and histo-architecture in Sprague Dawley rats., PMID:40032023
ERG transcriptionally activates SFRP1 to promote apoptosis of keloid fibroblasts and inhibit epithelial-mesenchymal transition and fibrosis through the Wnt3a/β-catenin pathway., PMID:39987226
CXCR2 modulates chronic pain comorbid depression in mice by regulating adult neurogenesis in the ventral dentate gyrus., PMID:39972170
Exploring the cytotoxic effects of bioactive compounds from Alcea rosea against stem cell driven colon carcinogenesis., PMID:39966572
Non-Canonical Wnt16 and microRNA-145 Mediate the Response of Human Bone Marrow Stromal Cells to Additively Manufactured Porous 3-Dimensional Biomimetic Titanium-Aluminum-Vanadium Constructs., PMID:39937002
Pax6 regulates neuronal migration and cell proliferation via interacting with Wnt3a during cortical development., PMID:39922861
Transcutaneous electrical acustimulation promotes wound healing in mice by modulating signaling molecules and mitochondria function., PMID:39921686
WNT3A promotes the cementogenic differentiation of dental pulp stem cells through the FOXO1 signaling pathway., PMID:39905528
For research use only. Not for human or drug use.
