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Research Grade Atorolimumab (DHF92101)

Host species:Human
Isotype:IgG3-kappa
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHF92101

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG3-kappa

Clonality

Monoclonal

Target

CD240D, RHXIII, Blood group Rh(D) polypeptide, Rh polypeptide 2, RhPII, Rhesus D antigen, RHD

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q02161

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

P3x22914G4, CAS: 202833-08-7

Clone ID

Atorolimumab

Data Image
  • SDS-PAGE
    SDS PAGE for Atorolimumab
References

Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma, PMID: 32402160

Atezolizumab for First-Line Treatment of PD-L1-Selected Patients with NSCLC, PMID: 32997907

Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer, PMID: 30345906

Atezolizumab in combination with carboplatin plus nab-paclitaxel chemotherapy compared with chemotherapy alone as first-line treatment for metastatic non-squamous non-small-cell lung cancer (IMpower130): a multicentre, randomised, open-label, phase 3 trial, PMID: 31122901

Pembrolizumab and atezolizumab in triple-negative breast cancer, PMID: 33015734

Neoadjuvant atezolizumab in combination with sequential nab-paclitaxel and anthracycline-based chemotherapy versus placebo and chemotherapy in patients with early-stage triple-negative breast cancer (IMpassion031): a randomised, double-blind, phase 3 trial, PMID: 32966830

Atezolizumab with or without chemotherapy in metastatic urothelial cancer (IMvigor130): a multicentre, randomised, placebo-controlled phase 3 trial, PMID: 32416780

Atezolizumab plus nab-paclitaxel as first-line treatment for unresectable, locally advanced or metastatic triple-negative breast cancer (IMpassion130): updated efficacy results from a randomised, double-blind, placebo-controlled, phase 3 trial, PMID: 31786121

Atezolizumab for the treatment of breast cancer, PMID: 32067545

Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial, PMID: 27979383

Atezolizumab, vemurafenib, and cobimetinib as first-line treatment for unresectable advanced BRAF V600 mutation-positive melanoma (IMspire150): primary analysis of the randomised, double-blind, placebo-controlled, phase 3 trial, PMID: 32534646

Atezolizumab for the treatment of triple-negative breast cancer, PMID: 30474425

Atezolizumab: A PD-L1-Blocking Antibody for Bladder Cancer, PMID: 27903674

Atezolizumab with or without bevacizumab in unresectable hepatocellular carcinoma (GO30140): an open-label, multicentre, phase 1b study, PMID: 32502443

Atezolizumab as first-line treatment in cisplatin-ineligible patients with locally advanced and metastatic urothelial carcinoma: a single-arm, multicentre, phase 2 trial, PMID: 27939400

Atezolizumab in the treatment of metastatic triple-negative breast cancer, PMID: 32450725

Atezolizumab Plus Chemotherapy for First-Line Treatment of Nonsquamous NSCLC: Results From the Randomized Phase 3 IMpower132 Trial, PMID: 33333328

The efficacy and safety of nivolumab, pembrolizumab, and atezolizumab in treatment of advanced non-small cell lung cancer, PMID: 30586539

Atezolizumab in Combination With Carboplatin and Nab-Paclitaxel in Advanced Squamous NSCLC (IMpower131): Results From a Randomized Phase III Trial, PMID: 32302702

Atezolizumab (in Combination with Nab-Paclitaxel): A Review in Advanced Triple-Negative Breast Cancer, PMID: 32248356

Atezolizumab in combination with bevacizumab, paclitaxel and carboplatin for the first-line treatment of patients with metastatic non-squamous non-small cell lung cancer, including patients with EGFR mutations, PMID: 31829747

Atezolizumab plus bevacizumab versus sunitinib in patients with previously untreated metastatic renal cell carcinoma (IMmotion151): a multicentre, open-label, phase 3, randomised controlled trial, PMID: 31079938

Atezolizumab: A Review in Extensive-Stage SCLC, PMID: 32990939

Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial, PMID: 26952546

Atezolizumab versus chemotherapy in patients with platinum-treated locally advanced or metastatic urothelial carcinoma (IMvigor211): a multicentre, open-label, phase 3 randomised controlled trial, PMID: 29268948

IMbrave 050: a Phase III trial of atezolizumab plus bevacizumab in high-risk hepatocellular carcinoma after curative resection or ablation, PMID: 32352320

Safety and patient-reported outcomes of atezolizumab, carboplatin, and etoposide in extensive-stage small-cell lung cancer (IMpower133): a randomized phase I/III trial, PMID: 31959349

The safety of atezolizumab plus chemotherapy for the treatment of metastatic lung cancer, PMID: 32400223

Atezolizumab plus bevacizumab for unresectable hepatocellular carcinoma, PMID: 32888462

Atezolizumab plus Bevacizumab - A Landmark in Liver Cancer, PMID: 32402168

Atezolizumab First-Line Combination Therapy: A Review in Metastatic Nonsquamous NSCLC, PMID: 31728860

Atezolizumab Plus nab-Paclitaxel in the Treatment of Metastatic Triple-Negative Breast Cancer With 2-Year Survival Follow-up: A Phase 1b Clinical Trial, PMID: 30347025

Atezolizumab Versus Docetaxel in Pretreated Patients With NSCLC: Final Results From the Randomized Phase 2 POPLAR and Phase 3 OAK Clinical Trials, PMID: 33166718

Atezolizumab for use in PD-L1-positive unresectable, locally advanced or metastatic triple-negative breast cancer, PMID: 31829043

Trastuzumab emtansine plus atezolizumab versus trastuzumab emtansine plus placebo in previously treated, HER2-positive advanced breast cancer (KATE2): a phase 2, multicentre, randomised, double-blind trial, PMID: 33002436

Atezolizumab Treatment Beyond Progression in Advanced NSCLC: Results From the Randomized, Phase III OAK Study, PMID: 30217492

Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, controlled trial, PMID: 31003911

A Phase 2 Study of Atezolizumab for Pretreated NSCLC With Idiopathic Interstitial Pneumonitis, PMID: 32858235

Blood-based tumor mutational burden as a predictor of clinical benefit in non-small-cell lung cancer patients treated with atezolizumab, PMID: 30082870

Atezolizumab in platinum-treated locally advanced or metastatic urothelial carcinoma: post-progression outcomes from the phase II IMvigor210 study, PMID: 28950298

Atezolizumab plus cobimetinib and vemurafenib in BRAF-mutated melanoma patients, PMID: 31171876

Clinical Pharmacokinetics and Pharmacodynamics of Atezolizumab in Metastatic Urothelial Carcinoma, PMID: 27981577

Looking for the best immune-checkpoint inhibitor in pre-treated NSCLC patients: An indirect comparison between nivolumab, pembrolizumab and atezolizumab, PMID: 29080213

Updated Efficacy Analysis Including Secondary Population Results for OAK: A Randomized Phase III Study of Atezolizumab versus Docetaxel in Patients with Previously Treated Advanced Non-Small Cell Lung Cancer, PMID: 29777823

Atezolizumab for the treatment of breast cancer, PMID: 29690797

Phase Ib study of atezolizumab combined with cobimetinib in patients with solid tumors, PMID: 30918950

IMpassion132 Phase III trial: atezolizumab and chemotherapy in early relapsing metastatic triple-negative breast cancer, PMID: 30977385

Efficacy of chemotherapy and atezolizumab in patients with non-small-cell lung cancer receiving antibiotics and proton pump inhibitors: pooled post hoc analyses of the OAK and POPLAR trials, PMID: 32115349

Atezolizumab in combination with bevacizumab enhances antigen-specific T-cell migration in metastatic renal cell carcinoma, PMID: 27571927

Atezolizumab: A Review in Previously Treated Advanced Non-Small Cell Lung Cancer, PMID: 29785577

Datasheet

Document Download

Research Grade Atorolimumab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

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Research Grade Atorolimumab [DHF92101]
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